{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ylSRdTApjPTqBCIPZov6UXX9V\\\\\\\\\\\\\\\/DMdJULiqiJ6CYG7n1b+uxp2Xuk+FuiRQw42QN9akJxqUmONB3LxCUV0DK9Vzb9Fv\\\\\\\\\\\\\\\/LqQOOJyJclkK7moJyaafcgtgmkkSGW\\\\\\\\\\\\\\\/35eAZE2ucSAqGazrU6toW32iug+KwXOQGN2Lyv+LxeNO+5VMK6MAWkZKRoWxZN9goQ0LJZFjy9+V\\\\\\\\\\\\\\\/TvutB1lhCi24pLmimvj2O4zRAMgtMCYAw1\\\\\\\\\\\\\\\/liEu4WQQ7+IjRcuaPD4wdKOBja2JTI9veUJg0qxs0eGPLzgBTymmoyomXDZY8YwejNHQGlO6OFrRZPOUYypMIIMi7He93tmWGKb45F4hto3wXY0ujNU81476BLyAVIZzsOee+J4JgnXMNEp4gsTlVqZUIUiouUik7LN+mirBpY4rB43ZoTdKiy+qeiEkcr3ZZLhr6+4nJiJeLqwvlGrbUrwfx5vhCp5cVjzR7bC8p8cjNEnuct7aj9S5enfop2JUhUWOhMrOlLBNTRRtIMgwQq0H\\\\\\\\\\\\\\\/5jUe340xD0jYFrLA2ihlWxIePwipGAZYo3VAj3b0rjhmdEBi6ed\\\\\\\\\\\\\\\/lOulA8WyAFiVUG1B6geQe8xT8UYs1HJWUR4s3Oxr7sbJaN6VRUKjRszqFK+4smG5L1\\\\\\\\\\\\\\\/DNvbkZjnlFD6We8xVtuCY8RSyKGM8D+\\\\\\\\\\\\\\\/nyQO7oJvxGAyRWV1TrTXQJe6RTaj7wKyE\\\\\\\\\\\\\\\/WM\\\\\\\\\\\\\\\/sObwEu++8Qzbufw6ndbapljoe8x2LiRmdyj4Ba9ZCSfCj04sneNc3IVVzOr7N8Ri\\\\\\\\\\\\\\\/r0SFUwv+iWNi+uPdfrfniUZ8A\\\\\\\\\\\\\\\/OF45hbksSnkElYKftoOZrQv9IuIOH3oBnO1l9Kw2WMmskU42o75Szy86ZhLvT27oXmFdNYQ0mYM\\\\\\\\\\\\\\\/Xkf9Fzqlr3G7zEqGS7rm7HSDnaTWRQg79+sAffr2YrWh\\\\\\\\\\\\\\\/7o50xOl0BOW5rYPgP0i7bBwmd1P4aoSkEZZTo9lJuGpUX+c3lUUKFHAk8fOrmWto9P+wmTL\\\\\\\\\\\\\\\/9MRuai0o\\\\\\\\\\\\\\\/iC5u\\\\\\\\\\\\\\\/r4l2C+XfMq8M06qM2MrYxLDCvTxa0xYEUaTNeaSKCGZ1ouWIocr\\\\\\\\\\\\\\\/p1bxuHXQKfmzKSMXqQxhuKv6NnUm36hXJW700S8w82dktbMIzR+5wO+lxKrNsuM2h9jycevoPvlG1G7\\\\\\\\\\\\\\\/OZUAyFGhb2VtmXIh7dDFt4DvhHFzzFQvZeylmoQiOLAXlkCr\\\\\\\\\\\\\\\/+Z19CZ8oaTlwNAZtl7hRLWUIhEp1vLBIwY7OkT3E\\\\\\\\\\\\\\\/CQ4\\\\\\\\\\\\\\\/2fOb3k9jnzWYSdXAGdAwV4ckcD2mI0uVX8TBg4KTJfDAiDf\\\\\\\\\\\\\\\/w5xr+ym3egTtomOeSKb6DkJzaUaeXpcNpTfaiGvxmmXqojBRQFoT8J2EuPFwUp3ffZvMveMxDM2iz5wIfoGGS6G8gdRTe\\\\\\\\\\\\\\\/JZ2a4lHV1RZ1P3CKE9YG4macYQoGpMcsEqt8nlaDIOYVAem78GRDDFehVuHYJ5q3eYb9CWq1hjYNW4d1rA1U9f0DgoNhjWqpsASBEdC2rP3hn321VzQ\\\\\\\\\\\\\\\/Oa\\\\\\\\\\\\\\\/b9FcaC2IFOp6RkiYsCxu5bLZOFvDt2aNDIp9CxJsZwdBPulOFoz65ExbzouK3+\\\\\\\\\\\\\\\/Kj8RFxeidbOBPmM0z4rmKTfqm+9hrlS\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/93pqTM9XS4iLZ4ZUuOP1TG5gOwoo2RmTxYrvsSeXG95rI4Rou2FdjncDgA69o\\\\\\\\\\\\\\\/aFcKdIXyCHnhS4YnhujpJtrmrkThv58SyQCjxtF5BR7iVqtIs1CXUTbZcmoP9mSOW+oJ1GTaSB9+ocIWVIGlw3gvZfCNUD60u56OkTrHpsc6MD\\\\\\\\\\\\\\\/SnpKsBDiE6\\\\\\\\\\\\\\\/iTWObf3v24vIWvhqo8uFAtLStYqfIz3O+qAKsZeIx11Q06ED1ZGeg997ql1GK1j6Q7isXqDdcLEKCcSiIjgkDW1oa2zVpr56aSshzM4fKglrPpxsI2c2ChqgOEkRUKdyD8yN4CqzQeT3KimR146onbmzkmeV9ulr27PSRY7zZu+ky7B219J9Zweuu99DWMN5MNFfwwsDNlLFOR98QwxJUpChN33RkowrDWbsxmKkG\\\\\\\\\\\\\\\/wxtn2yXgdkXjaLYUm58S4boMNO09RTxHUZ++H+PIh9C++Iq8bHLVvwOjP\\\\\\\\\\\\\\\/Z9XRNcJXY3l7XH4brd0LkOb0nFtyvQrKe1z9wAmegs9\\\\\\\\\\\\\\\/lRkdapMJgYkcETzUohdeaKsXnQl7PzZAPGACApxAyazQPey6AmuBQQCXbIly6Z354oIHYXnWgxozK0+SAU4SZUx9cBdLytKL8TEbcRdULso0E3aeB7EqX3aHsAb0e2zRL1N\\\\\\\\\\\\\\\/so\\\\\\\\\\\\\\\/5pyHOuJzHn9ya87rXdxYc9DA2K35Hc\\\\\\\\\\\\\\\/ResF4R95pL3+P1T3mxN2Z3GcPml3GFsMfGAhwfI\\\\\\\\\\\\\\\/ZdWL\\\\\\\\\\\\\\\/fNX8km1tyN\\\\\\\\\\\\\\\/fx5pboDqkDtYEHisbY41UDz82kMp1lc5IvmkA77BJwuo2i6Vaagq1IYMK8qVlKdtxgbZ2xTI1S9EO8mz2qMP+eNV2mEdisNPsyxgiLRUfWSTHtDKMAXr6heONHledD8QvG9rJKMBpsHJ7DRNiaVDbnoStOpCRHg8s3r24HeHH72QaIaD2pi7TAYkSIjuL0N1PZkr6SWRNM5BNgeflhX+CUP8z4K07ix7jC3Z9RQtwsSxeIIxvkLREi\\\\\\\\\\\\\\\/yKQkyRdLhQlVspHf6uZ6QIrDo5Odrc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022nJIQHL923BTB9Mi4RSdxxw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022378b945738e13b5c34637577dbd9e121788a93c68d0704af5e8bbc03aecd5c43\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A406.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A406.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0357\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0357\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0357\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}