{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022P\\\\\\\\\\\\\\\/2+dw7jZhVJm0BAvTun4HopaSJ20OqEqT7\\\\\\\\\\\\\\\/5oRvo5MTmQsgxA78B6LbQDxXZemHOhTiDZovxbKLUmmTIzx2Z\\\\\\\\\\\\\\\/wRzzMlRiKXk9N4sqm5gXexfkpKNt8Gpfn8RyOchvePJu6vhXbS1K43fNQQxqxmfgLfERzHx0PPqw0VA5G1rTT7cK31WP3xP0y9ocqjgyZ4nHum0M5J1b6iuocOe9Ltki0fi9uzQF\\\\\\\\\\\\\\\/6Jfnwa4\\\\\\\\\\\\\\\/U1Ha7qP1qrXji6vg6OYJ7qHl454Fh7dKq1nSYKQVxWk3bT9Z8th1xmnQilIm\\\\\\\\\\\\\\\/FH\\\\\\\\\\\\\\\/4T0KasCMuMRXJ0tkFy7R+5qqkik2Z80rvpEPUGRXa+OUcic2UcWSIwR8Nqv2Ar0rPH56uhiiVUfnQIIZ3KV3sHqN1vPVACNT64F40IlYTAcyUrAoY3XfFuFeLD5iYedVx1HudaQzpxmsZbLnY3DJaYE9E7ZtXazzUdy+SFmdaPejHeeGfLfUF\\\\\\\\\\\\\\\/qkJ\\\\\\\\\\\\\\\/65DTsef6iRoad0VRK2u+qsCbZp2QIIBI6v1BwNsQur\\\\\\\\\\\\\\\/JRqjrpykhdf02Cf2h8O5NB0r+1hzCchgK8IKZKuDqLSGpY3rnOoKecoZWnXkbpsc47R320j7pYbR\\\\\\\\\\\\\\\/0GYFvBtXZiePcUCi220kxSW\\\\\\\\\\\\\\\/kUhM1h\\\\\\\\\\\\\\\/4qubfyiFtjUIfqaJvPnOWbnrNcss755OU4cZoVrkVpq98c84hI+tEbM9NcdWvL7DfJLYKIxvg8A9i+0rEH7QTKt5GziO3+hqLHHtwiKMrTQD9p+\\\\\\\\\\\\\\\/20VT4vznkfYgZ0IAyT3UtzL5uMndhrxLUf8V5wo4DoMo3WRH+SGgRG5TIiQ5NuAppq4CTvxcyVOH7oS+ZABUYd\\\\\\\\\\\\\\\/QewfydnHV2JZX1wFZUw9W0I9tW0i77hMTDhm56hDxft+tkDzx+hx6Hfjj99WevYlEZOHhrSfeBhBZCF1MxcuqMc7h3sHTSh0iU4yVwjrgbEZTnB2Y1zklvxlXGTXMFNspL3gOhCAGK8+arn+EuVP\\\\\\\\\\\\\\\/mgA\\\\\\\\\\\\\\\/fwn40Nr64cJpFAlO2dpZG0OwVHsACcd2DbLIl2rBHogUWDap8tabbNjQ5MBptoYlmEqCKWtjJqUWg0z2697cfnSyzrt64enYDEOs2tUDfqMxBqKfs+Up7WMsnW2Q7wySlF7ywG3L60PuABWmmS5dtYe7jRX2zUGbtw7sM+jgXIwLqzQSDZZj35tG6HyD7cOvVpYo5c9vi0VhWuiFRWbmOcTSIWUp0diosYCfKD0JqQi8KMgIWrtCF7lOhY\\\\\\\\\\\\\\\/sa303y0XBPkAHG3ciIICuKxWW6uGuHEtzF7rHSChjKJCDxil3bGJSTfMd0Ro1mnaRG+\\\\\\\\\\\\\\\/96n2M3NSh6DNajLFqITyRlYlahNb3cS\\\\\\\\\\\\\\\/RQgbYXMv3di58jaLaxGbylSO59ml8QBxr66IU75AaLG+poeqQlpojKD3eOVM0\\\\\\\\\\\\\\\/kaugw5ufUsb1QdgTfAumAzTu1SYP6P+OUOoWEiy4uosxI\\\\\\\\\\\\\\\/F8wpD1ch5lEAPiZFMaOnLKhTWQnV+tDb0RrSWm4+M5IfJoLgO7kBXP0DUgNjkvAhC4Kj5Na13lsvLmzkFPTkJguNV24LVWIARjz+wNwxkWBdkU3xveYWu7r76W38VkyRCPdv+9n0jnk0mRTMMF4vWH0QzqMhRZ4mciGnG9pAqhKaW1j3KEhK5Ja3EbJkguft16+IhZVSPbKTOi3vxGHGvcCdMLiyLuP2zPAoL208RC+ffkGzMKytC2rHv3UUBWfWCyxZaqM9ohDqka9w70oO47Ft5FPZW5C0Xr8mtOj\\\\\\\\\\\\\\\/kldXpUz6AH1VvKwU\\\\\\\\\\\\\\\/TGTfx9g0ULzFVQS\\\\\\\\\\\\\\\/UdLf3ZdN16ls84xxL19xIFy2rdjMQiAe3gGXr2EP2E8KtQT9w3bYh5LKIAvBJUNLdKuWEqwVjyuXDLoGccHycB9P5hN4IOn8oTPV7NBbJ3jyLOs3dMTlcnbAOJ1DKbom1pXgCpM6PN7oPYHJ6oMjlHT2EX\\\\\\\\\\\\\\\/OY\\\\\\\\\\\\\\\/yH9rdxPQA8W8kZs0PfH8el5mt\\\\\\\\\\\\\\\/HKT3Y0RLkqOxwBjq9\\\\\\\\\\\\\\\/jpzq6B4TtY0JYGZm76+Ih9OiNOu8eLkHKKjLJT0mveZ\\\\\\\\\\\\\\\/oykerdEDgRforvC8t7Tx9K\\\\\\\\\\\\\\\/fr9ShWePGsNxkI9\\\\\\\\\\\\\\\/H4Ww5PJ+Piw1iKWS\\\\\\\\\\\\\\\/ublDyeBH1W4ZApEIWxdFdy8o\\\\\\\\\\\\\\\/Rw6MAgZU\\\\\\\\\\\\\\\/acBP2ttb8InB6gvPajeLm4HSJyfCh4hFIhV4fz0pNSmGxQs81NyG34gPiMjJWJCBM6HNyaDG75dG2e4HnaUcv3lEbaaUx1RIv+Dth45DitTcVn5WJh7E1+0xhzSZ\\\\\\\\\\\\\\\/gNVag0k5mb5ljNbQtU89g\\\\\\\\\\\\\\\/keh53DPiJ3PwPLxmnt97vd6WFuUkYuyKTwos4EoiOZ8uB+WR57l5PcfrJ+HsbUljhJJg2Vf9GZwZuA+jmrXigHSgFl8tOs1Y2leRDts+Rp4zSMcrjDEfZ7\\\\\\\\\\\\\\\/T0bhdj\\\\\\\\\\\\\\\/ut3HDLQGmwHEHWH8lM00GkqTy+zLygmdOEtzZYUF\\\\\\\\\\\\\\\/quhu4H+oJZMHKqAqXQVdgh\\\\\\\\\\\\\\\/Nh1Aj4I+co\\\\\\\\\\\\\\\/tlWR9eSmKDhuYr6TkINngFeMQxb+6Qz83HlJpvlqcF+w\\\\\\\\\\\\\\\/BFi6\\\\\\\\\\\\\\\/hzyUGxW9JV8oeS46MTH4oaiCFoX43wHm83QG9MSkC6QeruRpWX8Rzn5RsdUaALwSZwSYjodeTFMPN7gHZT9qgK+I5FDq2JVqc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022BtY3Qv2PgiwuiptDEvTs3g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022abfc6e478e462cb007c7af127a1c72caa2990da1cdcd1f5503c5ca1afce0c22c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1520.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1520.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1364\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1364\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1364\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}