{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022teFFEk+SMf+ylpDd0hb28jk82EycLMpUXTqPQSQ9KrZQUhqrjgUdWlS\\\\\\\\\\\\\\\/OkcbEu27QYe6nqka7GnSHuMoSX7IxvW9vS+U9DtB\\\\\\\\\\\\\\\/Uk88CU4qOvt2nTuIr2jDQLIYI6bHXaJgv8utJ7OxSoFiMde9XNrKhFP5tk3fpRfLnmBASF6EMnrUsxOVAt991sFQTydpIOB0pDVDrfvo9ZCqBTImWJUtiFqwoLsO3sGLINu+U5IHoZjSJN8SSy8KUphfuEabHEIjXxvJZ2GuHdeFFGYv+EvrKPHYKILoPMeGV5l8sgOoHMpVwM7WIiu00w8HZZoplji2\\\\\\\\\\\\\\\/ZbBxKavOFPnZe1eChPI190yobX2qPWBPwCcy\\\\\\\\\\\\\\\/Vw5zl7\\\\\\\\\\\\\\\/2pKmocS1WS\\\\\\\\\\\\\\\/1GSx5cXfkiKSgcuYHPAm\\\\\\\\\\\\\\\/hZPO0wI9EE4qH\\\\\\\\\\\\\\\/UTWWrxWEScnbD7qSKzXeSZFEdYUBJq9tA2njjzxMui8vbD1o9SBX8pUIgJHyJ90m5lC4w2cq8G68ORetSwChtbipaNAMGRRwHB2yeRCJGECg\\\\\\\\\\\\\\\/IpOBeGC8z54z6GloTWqDCyE2WAu1WBgZ63irjANZxZqbCjeJ+zx4vIFRCGUpoZbRolSzvqz9r9LVptVmu7AxItS6BIhvVKdFcpnwBrBGb7FYGZgufuJE2QJUWdSo6SBysthzT52CMBgnCupYlEGrUXVC69WkgkLpJyNpcpouUD8fncU4AjEeJ4cEEGpEeBAoFBmtRqXjqbnPBUGDV9ymyqoAVbtqrGyV+eLru0bDZfAxpFQmnUuFKXRY3r9FqYTclpYQa2UZ0ElBsAN0Rj4EsWunhIJ+3wSUsjUmBed+KjozEKiL\\\\\\\\\\\\\\\/2M0gEuV\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/LkGy\\\\\\\\\\\\\\\/ens\\\\\\\\\\\\\\\/JCi462dbpenTPT\\\\\\\\\\\\\\\/xSpxaYchNdseuAEzhZGevMk0BcKThmX7DcORYAnDaS6HFmX\\\\\\\\\\\\\\\/E+K4\\\\\\\\\\\\\\\/GOlBPDErIAwTKnZuW7X\\\\\\\\\\\\\\\/XjH5QN5+\\\\\\\\\\\\\\\/7MnOHVEAdw4m9hIfIasY3oFkxbi0tnFDTHjPtLFGdD6QWu2AJzmVvMWPXXcAOwJ06Sf6x3wXXBTM2kGbOIkx77g61Kv1pBdHLZkoleuN3mYcks1MpU6J3Xz21TGXRvAI982RGsOEPFHZ32nLH9mJOz3BmyUL1cTo1qf7xO4OsG7Ux1OHdQ53q2i9ruIEe9bQepGYV3QPTc4VPMe8TEhET2Xz67dBLWKkP1UJyZdLKshvuvq+ExqAzi3q+SQ2PM2KDn0x4NQUD1Dhamtg1xp4qpmnJQMD7u9uagUwBcWYdc0ymuAZCSxl55Q7fcjt0WvwV+mkjl5Y03tjJIrywVVVhiljLMIQBAT7VKgaym7PcM5WifWXaq0Ca+m5K+Ug0oSQyPonxZhT5QUdXaHNTUufruW35ujRG7Fx45kjFNoBjCZueUGylrxYm5E4f22dJ5sRIouWArzr95gLhMzQzOCNnfVbYymHIAl7vPLvj8EI\\\\\\\\\\\\\\\/Z0\\\\\\\\\\\\\\\/Rl5MLjk9ZCx3lBrBh\\\\\\\\\\\\\\\/fGofNf\\\\\\\\\\\\\\\/UugLnfVrkQ17mGXI6mH+\\\\\\\\\\\\\\\/BzMC83\\\\\\\\\\\\\\\/dxXgS8cFM+2QYdWr2udOIX5hzfLLKyFJWJ7wZtgbw\\\\\\\\\\\\\\\/0xrAMyle7iYLMp6rgv35y91Wy9mj6o4vtkp1sIPQdJCl\\\\\\\\\\\\\\\/9ql2Q8IX7Z1kz0qhBm5zDvvy4dFbJx4s6ZhQCc6B2ujQnDzoet3a6b2p4vhE7X1DOMFDmjerwr0NiIvfumTNwb02meE5EJZ+yuQyMY+R6maFqoNwvYDsoYY192kQ3JslhUHhl\\\\\\\\\\\\\\\/J6KfZg56LJc2DXQW9XGf2pRqo1gkEWLmqb2rVMsctKkny8tSGsUp5dlUf7M2PKIvs+LHkGYWX91w3X8WEAnSRBKyPZhLeJagHPOKzGidSyoUUSPT2Osx+bfDqrV+Jxnn1ruRzO4yhD8LYsgUuQ55cSkWMDn+AMmG900l8gnPSdzDzdrEBaNxUT4rYiHRZWswewEGtcAKpPFHo0v9a0qVL5wf0v+rNRMKLYcWoUs0hdE\\\\\\\\\\\\\\\/WMc0y1Bkr+tNapTKDJMIXyTlyW1o8ScDDA3bChZf2Y4pm53pO7za+bUZq7o01OPX1KlZPf9JEc7+X4T\\\\\\\\\\\\\\\/JpUi8pHmz73FuQGhIlaLMpQyDYLXHvKnt33htjoEPww1CUKbzNrV9fRCBAOIWtjryexAhuacM5qoPCS+nfJn9jFyhG6U2KZZomIFTZvwCO20m2aOpXd+apNEDBl\\\\\\\\\\\\\\\/45p2ep265GorcWr8w6IbFE7RmgKeWIpnKSEx7MtNcml\\\\\\\\\\\\\\\/vEI4B5U3N22yYWGeaHm\\\\\\\\\\\\\\\/nTeqEZvBq9+FLh0uyoscLncIlgUz\\\\\\\\\\\\\\\/K7c36FEnp2MfhVpa5xoiyum44ukOuprKPDAmdJAzMiwGeS\\\\\\\\\\\\\\\/ykTyuylNWS+9kAkPEFSN1mNJSA48qwMknOK5zVqWxZ6egj2xDOpYkkWJXzTqEeiqbPZRlYR3bfIElK1wZjeVa6j\\\\\\\\\\\\\\\/30wTaIbMIwaw1wV\\\\\\\\\\\\\\\/TJ+i6M5Wk+xohYc9uMrNT5s81ntog43UXXRLE9o5HsKqKRV6vUXV4F+mCQyFlFkuAwGXABefXn\\\\\\\\\\\\\\\/soDg6VbqLuxizsNv5dEaQvk8l+1Olo643Xsx8wXX1pDyBzUSHUaOl3jUxY9IHXOAf0t5NVOcMk2\\\\\\\\\\\\\\\/PpVjQglnJz5rfFoYfpFo5rvne8TpMLY3d2RGOZaFdwAQGS4cv\\\\\\\\\\\\\\\/moeh9z2Jfhg=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022WgnJc\\\\\\\\\\\\\\\/XZ+uppFY2oQlDoPA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00229f48c70da00ee8ddbc6198189928846d21afd6a0bb56c02acaec64322523b5f8\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1145.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1145.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1038\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1038\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1038\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}