{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ZM\\\\\\\\\\\\\\\/Sz2kSaYZhAL\\\\\\\\\\\\\\\/vRojmuqZc8TI0YsqWIA2QOmI9fs2xod5j2RcjIt0ff4VceaTtwTbk4VJxiEJw8omKGoNru2MNnXeCJpBumEDF4EP3FiNA5HEKMkM3GeF1sAy5RY7V7HbqFgzg0fEuUTggBxWOvV6uJ0PYJeTL0w3pS8XdWO29FkhGrBY5UNXB1ifuyLALtJfpMlWNOoSnsEf3esw4v78EjFhzVh7v4BFNtFgAIE4JM1R5Lo2UhJ6PbrG1TvOPrjzLTHcvO+JXdtZxftKnSv7WggQ4zG9wUcKmZ1G4tv1SUrJPVAphTc3cwotUbKQ4s05ak9yG9P+sWXS2TOhvh4DlNg\\\\\\\\\\\\\\\/m9zXLxNolE3aUZnvW\\\\\\\\\\\\\\\/KdgeAn5gOogBXurikfjbx\\\\\\\\\\\\\\\/kVmjFJmTZkR4WKVH\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Sfgk0Z+26ar934uL4Z24ViVeNzuY4Tay3npgMLnG8oyOCd1I9lEIuHW1q9XLyD1rouM5aC9fXUB4zQhjAwCTWO\\\\\\\\\\\\\\\/VkUMYRjJ2\\\\\\\\\\\\\\\/4Zfs56CpCl10ZCuE73V61GyQlQHcvImIqgrVNonZZD+UF2SPOGD5e9RRhhAmnsX6G4LSq246g+aAtr0LF2ObsLgwUjt5+e11UbmO2VSqmCzNXXv7JH2eQ2jadhRuMI3TrsKDzpsevQ8gZ0aCJtz28GG9uHa6tQxn0do\\\\\\\\\\\\\\\/QtKzRHBrsTNFqK0dt06KbUT9PZO2QGxxrsV\\\\\\\\\\\\\\\/xMa\\\\\\\\\\\\\\\/uDjycvv7d9kbw1CZvDIUtoRsEY7lJ4VVXRjuGsVh2eu7UOVX6Z22jdyJ9gnebbghYfZnrt96UrxYXGDpBWP2RLkU\\\\\\\\\\\\\\\/pPEuyxelOaS+lhjXMoj\\\\\\\\\\\\\\\/WWz+\\\\\\\\\\\\\\\/PDchzNIY+SHohLLkNwZfIlEx+0lz\\\\\\\\\\\\\\\/6YxRPvV5PZFM1Hz+AaQ84+9nmDtR6AhjE7VYimQDkaiblCNwv5yrs3mbXUXRVfU8uZixchtTglGDfkJTkWNaBLagZnucV\\\\\\\\\\\\\\\/Xo0ze+4ED3JYmZ6mMTshM58iZxe9ogmXgPtb13g7FgYYKunSSqwldgZEQQwGkSVJrKg3mIWWF8tR2qbwoZ1g55UtvnIzlB3sOdyfZeTJzrF60ce\\\\\\\\\\\\\\\/NPmFaCNophoND1P2PKtxoFBgEHbLrG3rhTGvrL7mnA8emWXIE\\\\\\\\\\\\\\\/7WfXiHxhB\\\\\\\\\\\\\\\/SoBCJ76TLtfB7MSfJ1QRuFH5mjnKYYKCN53a0hqyIC\\\\\\\\\\\\\\\/V9sa59cnoWBEgcf3enCYZgPHb03U4v0qWVkOHIDJdLtQM5Mp2eEWKokBUdUZcdjrtb9T\\\\\\\\\\\\\\\/2jS1GbpKRhoC7XPv\\\\\\\\\\\\\\\/PC4bmBmwVLh48zBALk4rxJ6Bc9t6AWFsWM5OB56WS\\\\\\\\\\\\\\\/Hevblj3LS9IbGuNH\\\\\\\\\\\\\\\/wswpPHcUZJHH\\\\\\\\\\\\\\\/biCgCqPvF7PFWr99qbY1yTF9EH8V\\\\\\\\\\\\\\\/y8TWpOHr+ElBpQSLd90YSDBsqf8mR7dRFOcd5FqRGvhoOqXxF2GR\\\\\\\\\\\\\\\/XDUgMVFVQq0iSvCfzYzn+M00PqpH7PsbLKJhFhhXUh\\\\\\\\\\\\\\\/e4NQtBrpXNqQl9cp0ZGUU9sceGO7LOzbP\\\\\\\\\\\\\\\/7pRYFhdLQenkyyg7tSb2tXbsj17I4gof9eSYzjG5w6uuQz7xN4hDEGD4LXYrdsu633uD1hjbfqt0Rn34qfpqKOnwF0flytf8QgtJzu2oHagGfeFgCe0+dY5WJC4FRfnNMIZ\\\\\\\\\\\\\\\/3kcaOy0V62SZWl4WCdsMqIxYSOD23oIwkZftGKmLWu5uGYzdQWPmBgWO05Z3V1hIZtlkHchlpSF\\\\\\\\\\\\\\\/Y2vMuyhSeVYkMwX1vK4yBjOPjoNHEkZ7mLlcKXaPNJLKz4NFGmtB2OP9Iz7JUMA0na1d\\\\\\\\\\\\\\\/Eh6xhDdHPBIq46oBBMVBodRgvV2PYQBN+h68V92zyoLeB312gqHSLDby64hoLyigiz8GNqbMmXa2cWZbwjFg60PiSgLswI4VL0umDRAEwbzm2vFU2dAmzvhIEHR3u46bGr+46VjZlQDXNhMjEr5ncO\\\\\\\\\\\\\\\/gvjrgFuba9y22uWJZE93cNrr2fbDuhccAGVYOqgooCwzS4v5LFIYce2k\\\\\\\\\\\\\\\/33FllcsQj2qcKVeTpmYxBmIYtm5Y0anFT4PO4b6qC\\\\\\\\\\\\\\\/r3iz\\\\\\\\\\\\\\\/jmZIrexHDddKsICwlMpd31cJFPEMgS6BY5ccPyFnsb1o8g2SdJXmt3bq0YqCKnkZB6otMtUpETqiR2IKT99zrzC45pnuPfu9wqDVLgDy5XwABONLUjL04ZNL\\\\\\\\\\\\\\\/cnVVEuVqNiXfRa+jv74nLKZ+CgAJIjZsCQF39CPAa4hxQ+fR2wt6bx1juypgR43b8iXRdS9cC0Gpxlcs4ecOGIwm9L1ka7Pu+M3BRe4G+0wHI6UKuyTtD0NKFjVTAKUbZMSgLhb+IbN8\\\\\\\\\\\\\\\/xPOtakjLeagKU0GyzdtohUCPiXXwNnF63LW5Iho8utj18TjJCwGLaZM79OP99A2CS3jmG6L0fXQPhLl0HIxaOQk0spVc8WJYg5zqqb8taQ0Q2H9FMSljddljTa8NUGsOzuEGXTPoHug70SvOfJ6cYGKqaTBEDDzBOdEoSC+834AFKHnFx700SWs2\\\\\\\\\\\\\\\/RBGgmvw\\\\\\\\\\\\\\\/aDAYSr3Y41frShtgfUZ2dV+8Euapy7Vv+AMwM6FYNdxZnvjajupJkZQ2Df3Chk32Ryr+sphc7Wt74mVLTfGxus0Ex4o7kQPj624vX\\\\\\\\\\\\\\\/Ba5mtWYVdFHUC1X+VnQqYtklYgPYYurB22ZEvw4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ZUy+GtZFClKsaX9hs98RaQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226058d0f337105fbf125b647b0c51218ea977270ec524a3ee4d00f2e38efd6c97\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1645.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1645.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1481\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1481\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1481\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}