{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022UO+Loy193q8klmqjn6d4f0JyTfHm0zHJ4a1ogM6\\\\\\\\\\\\\\\/pKnnzi+vpIy7BScy\\\\\\\\\\\\\\\/nwvUR5GzTguVjBnjYNf0Y\\\\\\\\\\\\\\\/n3xrdiIacUl69VGNsco3ceUUkxUxejzb90i\\\\\\\\\\\\\\\/iWZNZJSAYPXPj1\\\\\\\\\\\\\\\/DYVtCttPuLq2l2\\\\\\\\\\\\\\\/KIeAIjNV0tIaKyxK0cH74IupgWU2jvVIAFQUMnKFiy2JxXQoB7ctYj+3cyZIcItHW3+p7XnHsOCJ19oLoVppzwK7OpEWKA7HKQtJAWg7Bq17m+ukBH7JuVh1L7wkxT868ADjP4e6z\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/gvkzo4AEzXb7yYGxoZ1jBRXOOZZiSktu1VSG6YMVl3l9Wnhamj19LSUqsAblqEfFG7G+I83t35zIIiQs77Z5BvrJmMM8rSSxPbHU9s7bkZDhDF2hXIM9DCzR5bhNRMn5LrB2oPQHbrJ5WqimuA2DJesvRrG0yKqX2FhLbl33jGHVzCD+1cxSrrTsQIzIcNPGzeqoxALHqHo9IFrCtHFOls1t5Z1qTmfDXFvsygE2yR46I56AKP5I\\\\\\\\\\\\\\\/2zeXAUmz7tU8J3fuIQUjCJlj9QpReP1uE5PyBy4hbtSRzXVvaiZNiduPM9l4rsmedGnSKSU5wpGjM4w+HJKKAlz+OUAZGeRyUWVncwmVQYzid3+QQ\\\\\\\\\\\\\\\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\\\\\\\\\\\\\\\/3ze+I9fQVvfYTprALoayBbxBJXiCJFsePposda6HIB1qtQm5mrZkstaqfWDuzvuIB8KS6a13\\\\\\\\\\\\\\\/g1j3P\\\\\\\\\\\\\\\/gBzf4ghB4EOJbanODYl5jA5EJkETuE6eRFwOqZRVzW92t+AQyKGdrMiu0X+Guuc0VV22X6XIeQ+WAuj98BY0rtyU65oI7UcUKJvQhLVER44iKRWThjUq1MUoceLxsoWCGm0DFyWWwBWS2qoq\\\\\\\\\\\\\\\/9dL8ME47fwu\\\\\\\\\\\\\\\/t\\\\\\\\\\\\\\\/nf440Hp\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/NGj9EM46EUgiZXUpA3m0IL2CMKXwC0YH5tz8pRwWqlmxEBXxzP\\\\\\\\\\\\\\\/Q67WiWtrbOvS5scfda1uFmMXqPyRNBeZo\\\\\\\\\\\\\\\/iwp9mva8StmjwNeRYH0\\\\\\\\\\\\\\\/z2ZafC\\\\\\\\\\\\\\\/YTNlm5BrXw0ZCqP3ffOpzNIZ8T1ottLCWV8a4pn02\\\\\\\\\\\\\\\/oywX8WudSzphBciHVXHoGDRh7Y+cVlbxllpFir9xkiJPAHmDJbf2GDaCu4sRapE+chFrKqTCFdMLwpohzN4oznsQfdC\\\\\\\\\\\\\\\/XBmFFLskO8lpfePtMZDXdHq\\\\\\\\\\\\\\\/HPaOCzXCgJnv9mklX0fM3MUGoF0xgT2AenbtTGBiYr6wbpecwKCt\\\\\\\\\\\\\\\/IBxfYRkWGyO3PMNVbAGdhiMy2BMQTxmC9yAIlv5Wz6fwBdt7eykqiEMR8ihrRlFDAEiq6UYrgfzFxhIcwVq1MTjR9GW8X\\\\\\\\\\\\\\\/bJ2ptUMCCaUuBoR8pl8YRk89kaUHiiTsyannazj9hNwsbwzex2nLOqKGAFcomYiOtXzgkdTLArf6gk96AhDZoC7FFKGFxVaaigZsTyGj0+Y0hIjTMerSv+7UKca+myEJ9NLJSbM2A9+rnv6JiW5TT9cuXIbTEKO1zsp27MJ0h9iQjrwyQ5R5nUOWXSv95n9VxhvLtxiMpyI1v\\\\\\\\\\\\\\\/kReOs3PuD8S4DWoHEwmTgewghFDbJ5kimu4tXiGqEwePTZSBFspCCkdKQyU0YLkcVN0ukqiP0xvoCLYbKRfD7yrkbJUkd+mK06Ou0KOgYgqyPgurJ3QL0w29H8Z5AjFj7mWg+gxlQdSHggc6cq+MDrLR7Y6PuTI9y0+caWKfnG396z36NYwPzD9WFaWqaelH9S1OskBwh7DJMusTR8OEDhyuSOef17GYhp4fU7ikQiF8re3crLWS9imBDtCRO9J2RnKXUtmEp5RFqUZielg6TMNURiOlqDg1NFpxLqnI8dogZFv4AHG6kmBLS8\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/5\\\\\\\\\\\\\\\/Z9tMcCDCGjAUTlA3va7qsJXPQHN5AyTalSaLQlgzWzKOeSqIO6BKWNpzBEDr2OiSCdsLGZHOYhnlKibG+lygYs+KITDkazXorru+tjyQSq1bv0il5gWi9beOwbfu3erLvbXVqRrpvKQka9bfQ2FWn01I4Uqsliej+hPzPmbndJ93KpEEsdcUnaaxlfudE6BhLbiDjQF9eisLuUhM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022oE\\\\\\\\\\\\\\\/RgbrAoJH6NdP1EC7X9A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002270eee7e8bc0a3e6a710f15eac8e1512b2e23c4de192bdf7be1552b15ccabafec\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1638.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1638.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1474\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1474\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1474\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}