{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022mZzSPVnie6ZyXvHXf6hU+qb9eK6tL1fEbZA5rrHfva+pl41bZ75NrgBPp6O1\\\\\\\\\\\\\\\/atR9xQ78cbPuG7ymd\\\\\\\\\\\\\\\/0LIk3QUhKV6onKydTsquQxiZmnuwWK+Jftjzrc++goYQmpOzBBAXYxs3UIie2pKbjdzZerske6PZuiR3fb8c6JjnD3AXz9xaJIW5hIJMKmF0sX9Ot6csD2qY+5syqZB+ay60QC3c8mdCPhV5TCHnQ5xLlAiEymOMQ2Qf4Aqe5Xa6evDUyDIDZWqA8e4u3BfqEO\\\\\\\\\\\\\\\/oYTJa0g7\\\\\\\\\\\\\\\/crq8zLhtJmaYTK8NQSUFH\\\\\\\\\\\\\\\/u4Po8ejwbetiQSQAJ+FNMFrDQ5rUcprhOyrbRVX6AZ6zZbMH8CaxdKg+V5hQC34KCToPD3yaARooEzHeNEKUTyX8goMnN5RbXixLIJWCXX1vZLkPzehRbm\\\\\\\\\\\\\\\/E8akAzBa7N4ed8qZjkckJDMpxC20eoN\\\\\\\\\\\\\\\/slIupx4zxcD7eZjOrnGrAX85H4t5tTKpB7RpIA4PR2EXUyQ9BSXDbeBwukb5bn25GFDQrsaLk8anUV011QBfIwX9eUfGIh4qgAot11jZO\\\\\\\\\\\\\\\/Z2TfnIMStksDD6mEvWPWmRwg\\\\\\\\\\\\\\\/7g2LNKlGEF2TrI8upPocdr4r\\\\\\\\\\\\\\\/RjnnsyzY5f95IfnKrBplIlBSjnrjEvQVpH9haJgeBVqK3LrG3L\\\\\\\\\\\\\\\/kWsBbJRHQele42Vy\\\\\\\\\\\\\\\/Xtu\\\\\\\\\\\\\\\/r0dzi0gMYEDxdkLrfOPyz01h6F4jW+Oemiu+smacBPaDr9E2h3e3QJlG0uUKdm5cd7SbGU4KxekmjQFG6ujlPFs0E+raAGceEFg\\\\\\\\\\\\\\\/lI3h2WKKFpHJLZPnut6QWt7EV2SlaMNOZ3A5+A3y8RQpAeHDDGfehY9h\\\\\\\\\\\\\\\/5Wl95u8BsZBLjMsJisP8c0YdIe\\\\\\\\\\\\\\\/WDfMSRjkSOG2i7vJ\\\\\\\\\\\\\\\/8CWHoPCj\\\\\\\\\\\\\\\/+a2JgTanSE57uQ8DU4k9o5pFP7t\\\\\\\\\\\\\\\/zt6Lwrmu8gOKFv9ZzyWEMeom8oGKGNC3D7BU5AgMoDSxDVW+UpR1JdSO6zNQTQCPbF3IlxBIvb6To7oA0LfTJsflY44LOvTHAdxeIAkZUBOh7zF9T6YHfr+wJmi3BPDHKeSM7NRO5aKvhcHcFrXqeggwrvyv4APSrz45oHTsVhb3D3FS2ZdXEhACSuN5uWKqvnVqEtsstgVgCI0EzCbXWjWvX96VaS8O8DZsqm69pObJCRc6QX5d+X\\\\\\\\\\\\\\\/geu2\\\\\\\\\\\\\\\/jkR4+VVN5yXyZFT7MYdvDpbFwDyqm4mnG4dauyetfBVpFFDchQv3MVE9+LP8RCy40tzY9oaV9qfFz5MGpJCAtw+BESRGirxl+ALB5Bu+MWsIkFh9vQGA78qkBZ6Vg1udow3\\\\\\\\\\\\\\\/u9ujsOhbHpHy+4xFlwrBzIJxw+37cRpC7Hvkzo+LUffwULTq32LIMaS04iVJlbY+Nc5SFfJHGqUIQizGwKFO5uFxzCKEAgsS4+OwV09y\\\\\\\\\\\\\\\/rbYONtvsIr8K0BydtuYy3bAlvk8D2hKMKI2dvICAyBjc1vzArpcFtQOtIDVXapVvVtPymYyXXMr5v8WpSCEPjBLy1xFWBogyQy7A7UqyQFEvkQUte9YueURjwEBCBjEn9mRwdh00XXx\\\\\\\\\\\\\\\/Twnq1zshuFBPN+54xLViKN+p1tyMBZtt7UoNY7xzW4j9Re5I\\\\\\\\\\\\\\\/46LfOttz1C+V4NGsJ5YACP2614KPEqMwxiIZCpOUPeuM2nzB+9OInWS6HMlbOuRwhHm5vBdgTArSu5KxLs5ofXZjH1dMKk7Y6fFy\\\\\\\\\\\\\\\/tn\\\\\\\\\\\\\\\/QGyU8huf3w+q53lnE7N\\\\\\\\\\\\\\\/qf7mv4qO8cOx1DT1GpfHq7PuFM6EiQclpdtbDeBO4Nga\\\\\\\\\\\\\\\/Pu122Kwt7fvLUtBFUanL02qzYJuuoboZpNrWevjIG9kAWz0pynTghxsAd33ayFwGINSI6E253kz7V0IX3Cxxyt0FNWwo+hc3ImXcINBUN8cuHjgODqrK0NfFsoNLWeE73hIFmispczmd+GfO2GQwrQGhRBtDRMDAi2LoHNeH3bOqc2JT7eNXneNyFI87SxOPTCBJilEbEz6KBzq7LDowoC4HqTaQlzIxpelTB82r9YRH8j\\\\\\\\\\\\\\\/GcocpTHhtg9W0i5LNf5G6N1yXoXoi9SPFh\\\\\\\\\\\\\\\/DE4CHOjPbRLeOQh\\\\\\\\\\\\\\\/1smahpxchiVsRaaQQxeeF83GDu34\\\\\\\\\\\\\\\/4m3sA5qtJ09IjcMTl1KXEDn9E3XFWI\\\\\\\\\\\\\\\/Fr4prCFzCPvT4c4FW4hmYopfin0q5jLIAoj8yYIQRfRK6FEpBf7owv7Ov8DD7btpW8o7q65anHwdN38tB+Lb6Pvs3EYXomb1+Ue1ZU1lUZJIRiWjWxJb6fNwUIyOYMGOQz\\\\\\\\\\\\\\\/lrawl9ZfzJk\\\\\\\\\\\\\\\/E5sVdR5H7hhXfc99hmXDOJk37p7LtKu4i87iuGxoDKz2UIU0o\\\\\\\\\\\\\\\/BkllnrWjFXVkj4xnL65ejwlxCCcsd9FFwOGmttzrx78dSAR\\\\\\\\\\\\\\\/STS3qDRwS75zSn+Jk90RaaXE1gM65MBVOv8pMPThGnvqcxY+rqlzr3s8F1cZqcdBwROqaGT+FjAi8xyUc247pqPMeelZmfeTqIyKKeSCg7m467Rx1BL9xiJo\\\\\\\\\\\\\\\/lqfygFJXVN0SJORNotaUPxNS87mH2VPP+Vtio2+pqv6CyvsvRMIoIhq\\\\\\\\\\\\\\\/B18nugHMKh4VgR1hxtGLqIjtH8fcVwHo075TU6Zsj01gqCWjISkvN8xqdy5At\\\\\\\\\\\\\\\/KpF8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022LGH2Pa+I10IU0DzrAh4AwQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d835295ab3f29a9877e27811fbda415001b813426c333e3378d3f5082792bf68\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1588.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1588.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1427\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1427\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1427\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}