{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022QeaPkYYcTOYSuaw7Qd0r+eqVmZQ2iFfNv1jIBKgZNpBOm3OUIhwth2J5RWxNrVcvLzDGCfqMNvh9qKS1\\\\\\\\\\\\\\\/wGw7rFIfrpyl1u+gaT2bhOmy8eQzq0xqhBuO7itvdrn9rn1Mgdql\\\\\\\\\\\\\\\/+qHRBrgwyi8gMzeshQLypc+HVH2poCCCYByr\\\\\\\\\\\\\\\/dbbFNhO1p5pXqSvsdqGFhZR55kpSJPokAOzmRujxOYi12N1f+IPuA8P2urRaG\\\\\\\\\\\\\\\/FyLY0ZxcyC6jWmNyQS4P+9NBafmm7t70TTpxWyYmNXSKERh7KYsbO7yWDlp2\\\\\\\\\\\\\\\/J+6jIWYY5BF8+1r4PSJK1B5PJxnZq+uE2x4wjloJ7TldGRY1\\\\\\\\\\\\\\\/5PfRHa+xZ+g9tuUfuIFnVA7doxymHls9AIttPh6d5e5ipnxiTg00L10zX1eVyBDrc4j43zvT6GKqPm1QR0bh2BDsyY4Ma2fQuM1V0j0Ikz9N8+X++FJd9dBjZowPdnphDxL2wUwpZlMIsiBx4np0rSqBUQQvgmKGybwG3NZM3ryCUUxN6uZVwd8QVnaw70tZrmjicegCRZIQx6U+1fUEfdmU4BxLMr\\\\\\\\\\\\\\\/yabQFt1x3aEmBuwec7OHoC3LFkfLrfZMTFGxZ\\\\\\\\\\\\\\\/XcGruuD8Op8jbE2YwIo6vjyubOsv1wlR5pdQ7xpivDod7967ArTpSgCHhQFVLsJFWC\\\\\\\\\\\\\\\/uWGHrDnVDQeAckHU92yhFWqG8NM4\\\\\\\\\\\\\\\/DKmuMvgf2ttHjt5aeDJGZZNb2\\\\\\\\\\\\\\\/+lo\\\\\\\\\\\\\\\/111zlybFYrEpzGj1\\\\\\\\\\\\\\\/5MynBwdcAiZBWgdn3xzC5ivvVBEnUB\\\\\\\\\\\\\\\/+ELaP1ZI9DWytAqJSok0R0bYPhHJfSg21U5GqDETcEmMAlREIQvcXjzDiEvNkqgc1h95HpNqTW4t18xZRkG5YvpJrzUz9oeDrsxOU4Vy4UzUI5DRjHqsjVpfYy6hVN2wv8Chx5WG3x9by6k+nyQMkVHBzFMzTrYJNI+YtxIDUqThpMiJlsRpg7TXTPH+E5\\\\\\\\\\\\\\\/it5hU0BzoAYMlkiFr7nXXV\\\\\\\\\\\\\\\/Ya058JYY1MeHrwv5s+Pttk+v3\\\\\\\\\\\\\\\/NZZcLOeayq97wCKwuuFxZ5roKspORpwqfCvj\\\\\\\\\\\\\\\/X8RcOyhHdiKbHKIrg1nWI95KNPBOEN1bSRwWinYTL3v05FAigQTDEhIjy0uy2Q3YtVR2hRaO3kjGc\\\\\\\\\\\\\\\/m0YqMZzoOV9sGfyVorhbZPsPb4XIf4Nm9ANKNlF16eRTp\\\\\\\\\\\\\\\/PafFjYMmi1pBcwf8gtznMptfz0k9LoYQ6UZeELb9hd4Tx0qjJ5GNo+XZD65Xr1agxXDwkZZN\\\\\\\\\\\\\\\/culY3kB+GF6Vxmv+UTGyFz+8tjApsQDGjquJ0lbxn5VUE8ONDzh+fuOjfL7gjRpJJm9z2llK\\\\\\\\\\\\\\\/wxNog9bDN566T7L4iR3+ZMtdsTMRVz9OS0kKiP7y9Rh6J+QEBhoVRTWFao2CPVm5Ww5aHThuoO7CVMmRQkW40y\\\\\\\\\\\\\\\/Q+EE2m9FwH1CgycFYq\\\\\\\\\\\\\\\/U9U9oZAqNUzQMp3cjeMfn4Y5VancO3+\\\\\\\\\\\\\\\/4tpod0pNm5o8wsw5PKInwo0liAMa\\\\\\\\\\\\\\\/b6ILuuZb6oZnUohMA+hvusaY71aeA6ikd4EDdDGA+6hnCskySBXXwzC0JrRSgPDUSgl+FBA8Ym\\\\\\\\\\\\\\\/D0c0pF9e9iw25RvMifytDHWJ6rTKpz3Kn6T25lNHQG1OizaOqhDnA51zhFLf+H\\\\\\\\\\\\\\\/bE9P\\\\\\\\\\\\\\\/PyJK+WrLjo0wDLeB3xL0UX5\\\\\\\\\\\\\\\/75lJtZKC1m7ICEjnL5VaksRho5TA\\\\\\\\\\\\\\\/MGLy3womzsHTEFWEZ0134iys3RCD88m3BoAJ3pifKHuPU3AdLkpbo712ltBvYKvmBg\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/CfmRr+yktj2ykYiR37v+y10svBYaAAMiLPZetgSlfpM8E4bLm5B5AGSHul\\\\\\\\\\\\\\\/7FGYrcMkRVM4zE1BkSDZWLT+QWEBWqtHMTqwyBmiYcZKD0MA4iDYMXuyFvx7Z6zxKgDlXGACoBHJxk3GQXVTPTcQLbrcowG92+qx6CYQTuWBrQtN4MAaLSFXKnoNQf+bT4nh5cSIlDxXsCmTfOSrGIaEj6iWPM3YusSlU1hDjMpehsEp9Jk2a1HddSBw3BoYBHGp5sQHFKb5HMXyd96fIJa7eFnSld8p9bYbxs5OQcUkpFNvBAVi8lXcTUHk3Kyg\\\\\\\\\\\\\\\/9o+0V2hGCEb5aeuegP0un9TLk7MgbESgvwRx5EUcP+jvnJxu8Kpv4fGL6XLlMUJMGRxbSutExRSjV7MuD5K6A4x4iZ\\\\\\\\\\\\\\\/hBUCTT9VS0LxxH5hCpRVsIxUCgElN0JrY\\\\\\\\\\\\\\\/6fjTqGUG1f0ABajOy3ZyjC6sU33+1EjlrzruCQuXb9ABQyk0lrmMgUa6JB3JuWp9GPf+DEreQXrgeEhoUjTu9oCDZi\\\\\\\\\\\\\\\/5TwsR37WQG0nwQNT\\\\\\\\\\\\\\\/WOyvWRtH9MOP11KSMTXyY68D6lG5hjMeov4EbmMwnMnLzgH6+H0\\\\\\\\\\\\\\\/JoiM\\\\\\\\\\\\\\\/dY3makiMlPk3iDs7sEL1I4QfgtHo8OtxwpIZPpRQ5rPv0nwLhLhrVb2BtkJaFRCj6KYECHB77UV7zRE9JyuppcYIV7bpC5KIuN0KKoX0LvlJipfSPeXNGLYz7VFYZC5nVpws7ayo3JBAUY\\\\\\\\\\\\\\\/o1PczDbxKUlcRJqTfMLOiV31PU\\\\\\\\\\\\\\\/x41Up5Bkl7nuoaVQ2sAbpMCP+fHkG+SJWqlcORr593XccJzjDWf3fUzlSB33p+thB5jamB4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022oM5ndZD0phpldl7uPJjo3Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221067ac6fcf0ade6dedebdf1ab1106723873a665aa0179647f6890dea6972b841\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1416.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1416.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1278\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1278\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1278\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}