{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022MDjXeY3uOmdhj9+PU8ZMX8geLdVi8LIu6FG4Ti7nBeDiWSWimRVKz4zmzpwQRrY429i0qlYh2EDl5U4UJcOse+3MJBSAPpXUWyBVDtaYx9t+AWmqu1cbrxQDF1XglkvtxDs3IhL94ShkMjIvXIrLpgk\\\\\\\\\\\\\\\/GaXmvH1UceDHizmzL8qC0MzwprWeG6IOL6Zch78EyJ0LGRqdxkBbz2jNEZ8BXMOS1WWBIo1ogPv6afXpinbFzRPCrp1iCCdwo72feXFWijCPi+wzxiPDh57fF1TgwGOiwyPaV604AzqYT2fnoSk8Uy2FarbkKysFkIJWLQRSLwLHRaYf9bOz71+H\\\\\\\\\\\\\\\/aSxfsjUwDmTuzynBLJeLTKkrXghO++WcW5gTAMidFMvZti8mMjEhcZZlBBRDP7XFv0\\\\\\\\\\\\\\\/JGblQjcH8OAx+KWGLAQKtpB5qbSu9EpoeDxYkAw0PGjDRvvXRQ87+J6cSQXFKcsqH8Qm+q72sE6aXdRL7Wnm0oBxm3dML4k1IFSMTzYRUB1ZdAEc2SLw3gTJYrIkYOI2+CJRpHeWG2vHuVxhz2t8OxOXqtkxTnFAewrIpifXmueeaMP63ML7dH1GV5v+jKOAq\\\\\\\\\\\\\\\/ppOsP5fUnVKs2Mtkf0iOZmh6Pln2fCXlHstjS7FU2LRdu9UHd0fy+KRcmj2w0ORMAQ01MFV4Uw3Od+pr5p6\\\\\\\\\\\\\\\/qkB7TEjq8luTRRT+wtegbp\\\\\\\\\\\\\\\/ANVZbWfgLDMpCv1FdtadyfE\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/KPdjIXJK7Yh\\\\\\\\\\\\\\\/4cLK8p3UlNVTvDoS6f+uVZdFU5qgujzU1PAyqP9R\\\\\\\\\\\\\\\/2cNvlWfYf26UEa4KmcmcN9fZC5rUh1DMudxHjMe7fWjdx+F7gdmdsIH9nMsb9MmZ3I+onmhlBFxNmgip6K7EZYwPbdQ6e5vGCovC72XtGEidpEi\\\\\\\\\\\\\\\/CEK4iGsEfLBKe0euLYijgd+loeHTsfa0jyVs\\\\\\\\\\\\\\\/dw4AfHLDtt+7l7NzUGkqkxSTiLG7J0CgA+oDCNOusc\\\\\\\\\\\\\\\/61SjKaCj1umvej+3ZYlPe3o+eFvmBmvWLoNv+4+xAp9oJV\\\\\\\\\\\\\\\/6Tmr01MXo5ufl4qULwy3fgsKBHgSsbPwDCex+tMwkitAS9MRJJLnKt9kjNpm6DU9RebY6k3VQtkLP4\\\\\\\\\\\\\\\/IpYRK6enrN3zTizpn3AC\\\\\\\\\\\\\\\/0c4wjONuzF6vh4NEX2iqTv73KbDobkKaBQNquDuDtnWcxSbuYE7DGLaUdbHwCl38wuyhAn0T5JzZCYKFpGQAQBbmzoQlUQpgSCEhNc2FCI5zGUhLIHquLt\\\\\\\\\\\\\\\/rdF8zx\\\\\\\\\\\\\\\/252ic4\\\\\\\\\\\\\\\/U\\\\\\\\\\\\\\\/XioKB5w6wqhq9gJJ0VBpN0opvT\\\\\\\\\\\\\\\/IDKs9VAaDMAukKdSetHsVAmWleiktDNeo6JtCvMRHshMS315+aXJeG7b4LmRIseMPNxMxNjC010C8eEp38EELHgzZga9yXDdZ7y7SVHwzDx+XtNyFj6HkVrrRG8dkwdedo5uT0OEsz2LU0wmYFVbhBoFlxn6aYT6E0JLdtwgCG8F41OlJKo1iPBxIei15UKrmk0spB\\\\\\\\\\\\\\\/zO+IENnSyNqYmrjR\\\\\\\\\\\\\\\/BbNppZE5QpYjUmm\\\\\\\\\\\\\\\/k+y4SgGdNJb54ZWqshkZu+iVuWVQpphliDQos+IkO1DG7WTl5lLEMIKyxLrz6YKjS8Qfz52yFlTk+8K94SJ+GWzrB\\\\\\\\\\\\\\\/4ji+1JFQTwbNbpyEqngdjCzn7PU2vbHh7YZrscSaRmxT4rasEaxRGMSDSY6hnGRfMdUIDPKlBqSwQvaRiBH\\\\\\\\\\\\\\\/R4VUWnhA9mrDWkkuZ91YgcKMMXpvTo6UmMt9CPxBQcisw\\\\\\\\\\\\\\\/AMgag+eU+V\\\\\\\\\\\\\\\/YG1koUMzOQK+1FqF857AMBYouFFbyoKswg0iiRstoOP5wEGLQ9tyHLLaXM\\\\\\\\\\\\\\\/6ujpF28QqFH\\\\\\\\\\\\\\\/VfCmstdl4gTfCoe52n+b58NKQLLFAtTbneGAuC0GIj0+jjnZhDgGUXiWnrGivZP7X6tMuWLyRDqbkwU+BSynjc2MvbaPgbpglx9ZiKCXN5hHKgvJwOLYGhwqEbCPUjcwkonRL2y07q3mxzrrNCRpL2AvOPy0DVaoqvAEmlqmHRtSHIzqIW3G4caQDQK2ndvpCNLChn357EwbPurDm3I4owF5hvUdtXIJrXS2kMPMCjD8uUNYvXpk4R8IN4AW9qIgAB3kEeZGqmkT+QLveQWeiD0ajenTPSxpt1UAb131Vo9srnya+Ve1COBeAXJTETnl24e5j0KAwfZmqgQJrcqPK+TDWCsufIgXcYZrfyDnSkrHS5ThMSMBq4xVzy5e8uX4szIy+GBReGdw7JNN7\\\\\\\\\\\\\\\/wCa+t8B685mpsP5U7FX3wJtSsttiUI8Lonc8dexaiCFcCtiwxIfG5l54SGPSyyBIXczCadYNlTXSN\\\\\\\\\\\\\\\/nVVtnvfwC80AZ8GZEqRVntWg5nS9PPFXr6DVLB4xriT8pdf4DAwR3gA+LkBYbwOoQUDEADs2hzx4fijqxzhKTvcwrSDJIDQ8X2RCaQPy469vIGqB+7yvNwRed\\\\\\\\\\\\\\\/9y2DeOFjwU6PSW7GQrCxsyuCWLZlwt9PsSB8Nc9yVNnWeFwz8d9iPlvgmJNYyijeUaIJL3PzdGVltjy2HAMzN99u\\\\\\\\\\\\\\\/Pyf3oxIYTL9TJQzZ2UMnrpkwdIVxZj3e5g7y69MFOecopgyRTO6l9oJIIZkZHwG3+iHYHhePH1uGcDtXx5iv7e2OxdNF5U=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00226Db8xYysXEpULeJyL86XiQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228e34b000374b7d9a505efc131801e15d9956bf19500f4a0a94c16845409fe4ac\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A275.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A275.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0239\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0239\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0239\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}