{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022hR0JzGo+tGf9VHLia\\\\\\\\\\\\\\\/VMQ9q9RgsTcLnWGIOfPURcxgYXD3hrn8LYyWkJ3K3Z6bfHRWFF0w0gHxOj5nCIPbxcW+LL202NGUVwL3fMb8CNK6GW7jBPACyx5h9l7verur01u3hsF6mlPJ7YjLdeqeY1snATGRerx3VTJ3vkTx9WqmaYY83nUFZEkImOD+WXI1bW++5KcTqpvYv647ERcQ7nrAkG0qlguIYwR0HUPLjmMKTfqrC+uKTIv6Kdxn5\\\\\\\\\\\\\\\/mImLndV62urtXVwNpLOfviaCWFpuoPmFv9JYJzr7nsidwz3Co3z3rBTznLkx0H4rSlPa1HUe5RkJLsnMmNjTXc6jEhPGF2ds\\\\\\\\\\\\\\\/MBGMgEeAW8wvrjmRnjaepO4cd1Xy0rNi78T0oQNfGCXkQkpCVKNe+Zep4IU1gOY0NExguwjfos8f2JlVdOCp6LvhWw0tqdkXf4KBk\\\\\\\\\\\\\\\/bdq9cNtUIIyumKNclPxnNeXcAsU\\\\\\\\\\\\\\\/U0UteaqnbBViBoHxl8UodvGOanZk84tAZkPUOQXx+8t1dUnSqTXqVBSGDtQETpUBzmzxXVfNxnUU2wWy6QKKUw4EBkVyi6znlKlLJ4FJDPfZa7CVJzYbeXs1xCjV6a4K5F+CFIuIjGfoFiUHgE4Rut6HcyqY2Syqa0PYauZp\\\\\\\\\\\\\\\/YV7vpwyLzx64rLLGIWyBJAj4lLQbl4\\\\\\\\\\\\\\\/ieJONASbtTElu3sxEefMdI\\\\\\\\\\\\\\\/HvTDUi+vdCWv7WNb9SLHojKJBSkc1I0VhC6yI2pSckM743wD9JTTrXyJrwYP56zUVBx6DkmaX3zqzgyfE9ZA\\\\\\\\\\\\\\\/ZfO4\\\\\\\\\\\\\\\/eOVqwXwgzK0eNwotmwHhO73CeDfF8EYACGDi2zZxfXC6d\\\\\\\\\\\\\\\/YEmS3OmNKwNqIlVqXrcSUrWPApQdG8HsZaHwN\\\\\\\\\\\\\\\/Ti0XaZ83t2lLSGfuBn3ANON8QD0NCTtUsPWGPc4IU4iCe0F5VI1aq5R5mcPeZKQsNLu+9\\\\\\\\\\\\\\\/0zU50Lmc2cH7ZvjDNW5tzX+u+RTmOlgAYQcFzKliG4RQ9aNvIQ4ruzTyKqeFcn8Y4R4sZV2TzrwbQu4UK97MJUTcxdU8ni89ZD+B49PG9E6F8fhvOc4yYj1jH5rwlGDv9ElbVxS3mCybCQnsla97PdrgEECFjhEj\\\\\\\\\\\\\\\/+WRMmoirioD4J3Z+tOjrlQG7iQ\\\\\\\\\\\\\\\/eIGm0\\\\\\\\\\\\\\\/CWGRN5JcT8odgZXt2PGPvY1PLmLUAI2R+ty0oooxSvY7yc0lu2qf+G+DTuGk2UoVZDDgBLQuV3uevN2tGOvMKpAE2E3Lm0jTxHZj6wjiBL31EiQUrVkvWAIWgTI8KX1TQFHjdlv8eB6lmp9E43oB1DvffOvZuTmSNgHWPPNf4sUbJHbkf777Pcxrej7WXMvoFg\\\\\\\\\\\\\\\/gaQT\\\\\\\\\\\\\\\/sTP2pLX28zJdhtnOFYLCquiXxe0rDPFom1SktuBid3mrzkme4OmhXr0o+LWwImvJ2Sx2ePZ2JDVL1d9IN7iNuBN\\\\\\\\\\\\\\\/7aq8Kcznyd78BFNBx6noev0U8dJW2oj8ZFgwTS5tQDnKHon5hV2wXZJJU8s0p6JilDCUZaOZhfmDgNXHExx3nOoyiEyVjLYLb\\\\\\\\\\\\\\\/I8gb2aSgxDzqZ8llJ0qTGIFLiJ9FuuthJn6gyfpWHF9ISWdhis0e9Hn6pfIjSffFqb93i8Mk3rXT\\\\\\\\\\\\\\\/6jCt7D7ikiMh+dCNEHxrfKyKBVHKAWTuBtXe+wD34lHUX+epwOs6cVrXRDmEiVu2PzzNC0k4wh9XLgYdR7uLsGKXIrC\\\\\\\\\\\\\\\/yMYY6T1yqlMFM9uoLE0Cgt\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/vGrCcOCqWt+cxoeMA+w4L7MZ5mMtVWmgwaYIbpuOU898Nc+2IWMzjHtGnTyAhT2TDbjFLqa6U72nPyZRDzDErYkVDVhGXUvGiCtG0b67kl\\\\\\\\\\\\\\\/HJPhhjD0xxpcoN3y8j8fIYJBhHy8kRG+Zye08NK867Yj0hr1q6214ee6aymgYE8oszzTpjWoZWwRGchh6+R390+tVZNENsIB0+SpnV5SU\\\\\\\\\\\\\\\/KnVrQt2GIf5psI91nVSQvpqwbPuOOWzo2BkyoK9UHGKqIgkkWsHWNVa8i5UASDIfYbQTJtO0l9j\\\\\\\\\\\\\\\/1gCX2lAcnCQTKrJ2tmyA39H+wrNgl1dF3QblGwkI+t8\\\\\\\\\\\\\\\/CM77qxipn916X9lOHxAc8wIuD4Gd+NNFaoYDOQRyAb\\\\\\\\\\\\\\\/mGvlEKkTdcUm4DbJODLeT7nGEcgatAGvfHNwco8gJQOvXR21UxbbfJsoIOH22RDmMNedr07sAxlpjgjHFxPTyY0+zzeG9PCx6oKZv4ENj0GS9O\\\\\\\\\\\\\\\/3CdiUtVBtXhBqouzlrvWMoIpAVz1DSmpK5DjuvpwTooc05SgW2Q+gNs8JLGdsZ82iDn4d4LoLbWHcCLJYfbFTS3nzSoTUvM+c2JR1KKvKJHkaOLkUs7hozGe8tMcNQzyle9dTekwB3eTrY7dD0d2acnpNAiatrGDhlWpAmIdOOKPDA92YETVkR\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/CBPHnfRSojNXnPosLMzdQmN\\\\\\\\\\\\\\\/+ok2N9rZK8QZOZcWpaZLsFkic0FPuDuYs+\\\\\\\\\\\\\\\/DUbpQ01Qi6WUrbNCmk3\\\\\\\\\\\\\\\/2xDM6n8BH00ccNcVZ5stYoVmJUmy3f1tTa0NxRPt2CdFoI\\\\\\\\\\\\\\\/Q+8qqdSwLn+uMAMNBTI\\\\\\\\\\\\\\\/JAPLwEU4c7IV1CIG8J9fAdeWvezfLADIZ\\\\\\\\\\\\\\\/Nczgxkz88vTpTfhUsoWQ5awHTSBuGx5XU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Vknd5y0tmrPbZLCyKMX2Ew==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022dc06ea34f8415c5e0359cc3c91a6540a3b8705bf08db0d655197d22a5dfbe8a1\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1397.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1397.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1262\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1262\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1262\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}