{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00223Vr6ntDZ7cLkRIxfKLhOcaQwlDLxHQpr+wP2VGv9iMe\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/uJFJQPPJk\\\\\\\\\\\\\\\/VGRQmWghKN8T3B5mOF7Tf\\\\\\\\\\\\\\\/+PIqfdDSWIYl7Yl2G4b6AGZ9KUwozyYW2bk6PPDpFC0YpSy6pYfq5929IisNzhyXgmnjdWIL5kLXChwingiDPsBoyMryJ46148Yhhj+ZMrQYRJ9Ucf4Jv3ikrkAgJA08zWZrZeOJ\\\\\\\\\\\\\\\/dJwvjuTQuaquYryX+ztsLxFbEYaPFWAq9ZYkqKRviUbW3PZGxC2a+hZYMVsYHcttbxavxfhbvUJ5csGefmDQYW33LUkt99DVQD361U0C6tP2Fnpc5IiTOcdt\\\\\\\\\\\\\\\/pZE7bRXvte3HK64gSrp4LEuGsPclJrzzNInF1idlYAszgQ4cw\\\\\\\\\\\\\\\/RrE2oECIMb06EGuL\\\\\\\\\\\\\\\/IQUdte\\\\\\\\\\\\\\\/mQ8v4U\\\\\\\\\\\\\\\/PyX2u43FQ5M+5oHZPYhZzo7ZLVeGir9nIT9BaboGBhd5wgSm8ziH6xMr8AIHuknoJE6W\\\\\\\\\\\\\\\/M1orsQRiK0Jm5\\\\\\\\\\\\\\\/aoACtHjkzJKoeVymib8Q91iZ8seFyMFXZ\\\\\\\\\\\\\\\/npyldhvezt9zdVQYGYRO6jk7LftXenVgvSB8efhhrITVG\\\\\\\\\\\\\\\/Q\\\\\\\\\\\\\\\/lngXHVTUQAyGeUqfz46zsU8Ah4rivNTy\\\\\\\\\\\\\\\/hS86S4p33cq\\\\\\\\\\\\\\\/CAEWOSTfAlRXejivRFoFrEt+cwFx2iChLetQ1H\\\\\\\\\\\\\\\/bygsB441xLIhJIN5h6EuZCe8KO0D0d75vmWS5HVlvXrFJOydwROLcWAnDYuTG9HfZWa\\\\\\\\\\\\\\\/brpYcD8BYeJXxHcv9zwNCEzZ\\\\\\\\\\\\\\\/JbgSfPKjrii494upaaGK7aWzcDB76P+wszp05REa4MHnOBmZ1JzKm\\\\\\\\\\\\\\\/LBtUgjwKXo4QuZGXNfmEzDnE49IAOiJPdOT70KmHX0rW8nKI7ialM4P2835KnwqijRHrU\\\\\\\\\\\\\\\/K2R+8YVeVbrFjmWKSnygV+6Z4EhDNSJD3hleQAey\\\\\\\\\\\\\\\/Rn20BG0nVDlm3Kv4bmReUktSwuPe0+c\\\\\\\\\\\\\\\/dVNq1LdwajBZPLdNhB0sBPQyAbsNoeG19sBrupmZLdb4YX\\\\\\\\\\\\\\\/xPQQGJnV4Iwdak9FCyRmyYrjaMhtsxecyivD4YjNXd1Uz0p6S\\\\\\\\\\\\\\\/FFEgOywa7d0Te9H0AsAP\\\\\\\\\\\\\\\/9TJbzPZUxIlDdaD9fAcee5KTACf7EHcIEKmiF7jY3T\\\\\\\\\\\\\\\/4KdPPWSQ4VmgSvpc1+BaoyrFK+4RHiKLsXkxKH7BB\\\\\\\\\\\\\\\/u28BbW9Cw3MVM702zJBT4UAyNpXz2LLkwDZ4F22YWFvGjeEdiqcSIE4cbxSTQG99mHvENhCm1V4YNheoeAPWv84bRaS4C7dFxeV4R01BDVHO3d5+abJnW3dZpXy4Q13BtOvLcbOz614NgG\\\\\\\\\\\\\\\/QhzK7wg90BHJHRWFi9eS\\\\\\\\\\\\\\\/g9feZnF655WPW+DaJoaneRhDAcRv+7CYmuv37G0pZj\\\\\\\\\\\\\\\/+K82aTJa8GPHA+Ph7njqEfUQ8DRpsxGEVYGOFGJ+WS6CUCJp\\\\\\\\\\\\\\\/ZEf8y0zf8Odrh8GZXzGRABIU+kWihBGD0azytNlzdcZQlhkTP+qadD3XYTHT0uirkzONQzWRP+vgf1Z5XeEAyKIZIdhpyCCaKRszrQ\\\\\\\\\\\\\\\/RrvIVBUYSNwpig9a8Xh49qKHmVOmh\\\\\\\\\\\\\\\/daEJEJul9kbHxkvJgHULNHkrS1qJzg182xGoChw6jwv\\\\\\\\\\\\\\\/l\\\\\\\\\\\\\\\/wNZ0k9Yi3t0x70AkM8gCS9U4mAeNjE+Bh0zqICLWdhEYvn9GhwNv7IvqjhgPcGpznA4myi5+FMy+QdMHZ67Z8n5HiOql0VcY0C4vdstPkBX681DUhCAGLfia6Yvi+I\\\\\\\\\\\\\\\/e6347UxYapCnmbGy9r5AWXczRDid2X3X+w+OXrLtV8iRFDM\\\\\\\\\\\\\\\/eOHVhODSxKVDnkOV5w9do3v5cH26r21huvrLcO0TslmlIgZODo512\\\\\\\\\\\\\\\/1+eWayMTGmpiB0jbU3x\\\\\\\\\\\\\\\/fWkmOqx5CWfVvd6POaDnpN0AcUTL8udi4Q+6aIPFaTA6yCF8K1kK5Qbo75JTkRbIbnX3s8\\\\\\\\\\\\\\\/yhaZIydwV1kRiGAFEKD7JMiY6REm77Cp5cbSrxyrGO\\\\\\\\\\\\\\\/x+9F+Au2E3dybn4TNIe9IKLYLCRMbqVSrKhhsaqg3v7NRx3HlPwmzf2sSvyXtBFpQBN11M+nqm4kQcVrpytTT8IThwtu8Idz4i9i1hYfQKRTOxGw42pHeBA5OhIqGH6bZoeJ2ND2QGhYdVQwXkFin406MbiSGBiRQrQQllgXhvSSh0IvF2B7v6MStWAISa5wkwgHVowmj25EDOPtj+1swIq3CI2EPJnTdPcepYNZiqHqrUiUxJLI3GzH9igfcKs3cqpA83z7s9KGuh8shVb9p5WrPFNil+zgVHERc\\\\\\\\\\\\\\\/P3yZwcuOmYY1tjhvydKtixvPywgJNgBBa0Jm1ilvcyz8SHGTHAUadiYnua55b+\\\\\\\\\\\\\\\/ALDRSbtSiMnLVV0g0OElV5Ou69X6fqeA6yXBsIJahqxu3YajvgFCyEU0x7DYqmcJEf+MA0yTajutbu\\\\\\\\\\\\\\\/LDDXiLvyojVh11BT+3YRUBURjkjGGFdXmqDnzXoywxiTrZX9OPRmkB4GqnnoTGtYcTQy02IY17CrlH+kONsu1+kDmNaWLBcoXhP7j3AYpTGpurL13SgIqMPUeAbEN9nrG5mXAWx49jxNMCochgyaYV1eG55fch41XDTthcGJIAm+O0aHyTPZcYDPordM8S8tPx89OT8FA4RxXYY6HJk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022tQVXJV4Gs7NeC54yc7nRrg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022bccf0d44112528412b2f157835f77e98ee4b5037f92b0c9c8440416a09d6e083\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A878.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A878.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0781\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0781\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0781\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}