{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u002202Jg7j3ef8q12GDP1I7IH+xD47HW6t0VrPMUjIlshsvfvPyXjkYfeRSfztkdIGTPAKqrQJHJZaby7SKhJ+Z\\\\\\\\\\\\\\\/hfC2HbC5pTV2RdVA7xvIMTR+POZcf7aDFT7oviX+VQKxRYJG9xIl7OrbRnHVk2hgZwdH01BldFNyZh9T7lOLFRHCca227gfLJU13bbrxZy\\\\\\\\\\\\\\\/SAWLo39eNCprml1cNu0875g7Ty9YNrKwDGIb62BNothgztIdyBOPJPMGlsgtVOrGHJHZ4OXk\\\\\\\\\\\\\\\/bRELVIOpZCWnhJMfsJyQ8P42IFm7OFw8dknJHR3bXbjIbc5L23QjtyBmI9+pcrLtSzrrisHCTqFpXhuKTyOP4nZy\\\\\\\\\\\\\\\/4Gjq59bqwFghkto0Ol6F+2RFrvsdPJJ8U6foLFe7dkJIRo+dSmrMYZQq\\\\\\\\\\\\\\\/Q6PM99Mjtt5feMzWy7W3Ov2VeR+E1dhvHDFOYA8l8Kh8PRazsV3xX7P1PWwszyKUniQvRWeVLTW8GX9ZXmv6Sh0iQnVde6gRKhVtATnoM9ZQlq7ufdaPRliMaQzYTj2qacOupAU\\\\\\\\\\\\\\\/9baBWmBl2mqJpTUeAQSWZUEH++jUuWvGLCvswMFWJah5wtMvOu\\\\\\\\\\\\\\\/IFhVcfuCw1MhLcPvfnVzbPym6naU0lx\\\\\\\\\\\\\\\/jUgqZXDwnVN6GwtAf2DWZAflftToYkFt3b+tRSp7sFQgjqwWErPeUCsJcSzfxzxFih3\\\\\\\\\\\\\\\/CnUHaFuRm39oJn45FwzVYKqjYptWOWUKipqaVJlc4TNXnqRHc7uYokfUul33Gpp\\\\\\\\\\\\\\\/CRTL6VJTzb6YFyasW8Nd0nrhbR2oCM9CJGcXiWZyH9DoxkdZKssNFvmhKSdVS8Br4yAYuVao1toAaIcrsYk5dYve0YPkz27NnUWJhJgu2aCT5GOyGmo4VGHG0GcMUbfBrqoNPxgfb25dkCwmsBNAy6objZS\\\\\\\\\\\\\\\/ex6HUXVAxiiV9jKxEpt+1rnFa2kGpOA+FLBOzXzo1iI6KrfAsMXzfbZFkXBqV5NXPDuXNa7nLRPZoZPGz\\\\\\\\\\\\\\\/MRfLtCwGt4ckjgPxfycBkQBNI0R1dv580lSRYwOwPk5Ppwahq2oH311ziq87mt+ZszD8obvqjKh38t0oTP9yRPLLWyKpQrQWep1hXoyCLaQ0jlliLiz0IvadMXlLXh+9EzWDFf91gkpIvmRNaKItrYmoozF\\\\\\\\\\\\\\\/pfWrvl3JFg+K2eG3fdCWNveND5nsWSjnH8\\\\\\\\\\\\\\\/Gg4jmCQFzNJwEJfZGmQh9NGwzo425MHfa9dC2hDTAbwMltUUlKkMYOqbeFNU8MQywkQdBzkdF6pm0Xh\\\\\\\\\\\\\\\/FllNGo9mwKsJb3C2X7lO7xhMOp6jkG78tijrLbQcug5myTC3MWp\\\\\\\\\\\\\\\/+36lRBOagSL+xkeRWcSW4k8H8plqlv+2Tq9gYbKCFhHNWqZ1Mga\\\\\\\\\\\\\\\/vCw+IHfv+u28rMApeUMY5HGSHwFk\\\\\\\\\\\\\\\/C5zY5D3NWiJD4wljtV+CTtGb\\\\\\\\\\\\\\\/ze1gAra+RFWtR9uxgfDNFrVaOTsV\\\\\\\\\\\\\\\/4opVcL+wUpp+svil6oXYs5+NDgiRsE8Z3Mz4CrSNYrmEjU7cUVNUsBpaFfp8c6Kjdtjwnl0LDI4iypmpn1x2lQRaXA\\\\\\\\\\\\\\\/Z27pFUduWrYgNoJyK7jbY8IdgRpU5G7K5FfsA6cRt0muu9Za7Veu4VSdabNLCfrGfsgD6u1SjJqA1Ehas4IbiUHe9TuGLkaMBsc0iW66d1c4h96bNUvAtO4fg36UurLUgvD64i\\\\\\\\\\\\\\\/kuHywKcOd5DmmLdzBWH9dJ5PDYZnq8Gj+0kR8uVdu9szmErY7HQb0RY8yALbyEpaqHW8GAR2JXNATrgiFjAwDnNgyllSWbYu610mJ+ixVf\\\\\\\\\\\\\\\/xJVE9qFbTi0NdN0sLSmskQZGy5I8JeV+gzufWRbbSCVKZ3mMpNngeWu\\\\\\\\\\\\\\\/UZH7Pjom+TyUvFwpGglVkA+puun4t5SFO4yas99TM0tZt8lPJK4H+KPlvwuCRO+Ei6nVtRdT4JXz\\\\\\\\\\\\\\\/Q6cEBtXltG5lcXmubbUjXhosjZdcW9sKrnF+t6+39EzC4YqY\\\\\\\\\\\\\\\/o3PEXArEgshqIF8L8MS9v8YtVrNTbuR2U9NocrMkPj6hxjl1LI7RC5dLtcesMwWHTZMH9+VYj2z\\\\\\\\\\\\\\\/0t9jBCxtUR919ePGp5BIGBGcMQvtAz76ij1OzCOfT+0sFVzGhklC9h1nQdb2nV0Wdy\\\\\\\\\\\\\\\/DuIWggQidNV0w\\\\\\\\\\\\\\\/RNGvxovPRjONtWCdhKNmSUlDWyIVr0SyaPOYssvk8mTwYPq6pRqoQ9OjAP\\\\\\\\\\\\\\\/KM1e7SkeRIiqt5LLWQR9aJsMbqb70ZGKnqjbrSV9utYesWu3Ce2\\\\\\\\\\\\\\\/Eu72NC68IU062N7CU5WvGOGXDOE9qt7M9\\\\\\\\\\\\\\\/xP6qg9uSwr6QV3TCDBopqKlfSxZDz4w94uuknUuYC2EfXVciTgbSacuSjcT+YUo22jDZAvG0\\\\\\\\\\\\\\\/KqYNCPAp19PKg3x7A5AMahcYDHvXAlCcd4L+77lD3ty9za3\\\\\\\\\\\\\\\/SBqz0BQ+CBhi1MYVPJIRN5r2jMuvIhtwNsxUJNJs1pEl5WYPqVPwVvg3ShxH4nS8JXfLdw38Gh9D444o+4dzGgqJu28aRTQas7brenJQ\\\\\\\\\\\\\\\/zddkI0P1fh+\\\\\\\\\\\\\\\/kaxCSx37j87FLkaZFZWdeL\\\\\\\\\\\\\\\/SZ2xLyFtitqrYZOhqq2sL9Ivh5BZ5AleYXRH4TCbkJbWcunl+dKBDyINFmzcGQhWKtkA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022gm61nrrB\\\\\\\\\\\\\\\/d3jy9EfdEiGcQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022addf4cc4ccb7ad4019eeaab0c3640cd5cb484c222d92ac18cd848c3a92877e54\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1277.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1277.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1158\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1158\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1158\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}