{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+I6SdOREgMfRgPgCqHxXMNqJAJHhXhWqU6lzuI0Mk3MKjpv9Om48Yf7rqN2LCK\\\\\\\\\\\\\\\/peAo\\\\\\\\\\\\\\\/SbPpPGDdTj+ycVyxP95pay761EXg8qDCwYsnDnVXXbGlb1SlJab9dH2FD0H2L48KcYD3GTttIHvarqIVrMA\\\\\\\\\\\\\\\/c+rYVQb6\\\\\\\\\\\\\\\/niMI+vqsFpsWwjgcdJGPE\\\\\\\\\\\\\\\/MAyxi0FvcwqXYjO5\\\\\\\\\\\\\\\/rUFJSNonA92HxQqB5GsfzffmyeufKTEj6QpO5YvqJ2R2Yfe4F7yibmr2r2o7dKh8t\\\\\\\\\\\\\\\/WIJNa+U+8gLSrMnzRwM0QwPgtCF0nhSG18bVUarss30hrGT9yQoUQsLDes1kOIv5claZ4TuTXA1wwesYPnJVIvw+R3i5mjMGAvl8uNvP16hXwC1Sj+vV\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/UDEALWDjq5UFpmLjSmpnKM7Ccu3ZtcyG4Xm4tKOE0FqA0bEpMo0EWVVTFhI05MuYH2JT8mkLU3Q775rJtB9WF4Qmm6kRm6tRwnfTzy2Z4k1SKze+KYC71ul5hjYkwT0jhqivdFvQSZBBPZ\\\\\\\\\\\\\\\/AWrNpiX47OfpCS6dHKL\\\\\\\\\\\\\\\/q\\\\\\\\\\\\\\\/KZvyUG+zHaCv7krE64RrJuOpCj4ftADBABA2OP5QpCyd8yOaU8c2NGYH3PJyC74N7fyHGk8Gn2IRX3A6v2zU6cUz+vDEndoMU\\\\\\\\\\\\\\\/gTSxjY3Lg8tNnstE0JMbKgdBs234iRPIdHghgxf62TsNxR7p6sbnp46DsHtF94nlczfDJSqmeNG3iRNHd0alFTzSK8ic036yX9ui8LqQfcZPoXMHKULGyvFLgURnhE1N38Olw1yP3M5uLH3s9bOHsIXctxhQIok8NenSHOuZYj1J9IXwSyHJ4YvynSZ8IKG2TSmx7+MF+jTKNllIzUJ4pTwUOinC7O3hsp4LF78bL0PdhaiRa9JMALeRFQkRNhLXRbgRQKLljMMB+WEa+oGJEStASTzBjA7D3J+DEq5YGsfeykrVGZQX8ZChAYyCXqicYzr9Xvky6TUxXt0Z\\\\\\\\\\\\\\\/Q3m1OHBeQSOVICxfcyJNNR3lIdgSAP5EiSAcN4C23+PDwn9NqOqH4eiFV01APEfDS9urVJ\\\\\\\\\\\\\\\/CHJbOs63\\\\\\\\\\\\\\\/Js9o6YO8USm6lOMxRx83rTbzjWHuuvIzkqYbeeOTC8GS5NSZSc12+NHMhonWsD9tJl2jCSrrKDXU7yXp2UOs0qXuMgapLGSx5I5WaqQe640HHRT\\\\\\\\\\\\\\\/FOLhZPTcjsM3yeHTSWTZIiveJzSNOK0tczA1eoXf7kHfqznt29WXktNswDJ0xEpFmceHaxjmcmkOaTUdBBa4aoDLGR4ZdDbARrP53\\\\\\\\\\\\\\\/silXMTd4XppU1s4tjKtuYYSOgcSAeYui53fMZSyH4XR1C8\\\\\\\\\\\\\\\/t1gUBg4pDaXN8p42p12yMYhTZl8QGPQL7bGgXSuPIg14qv08j2MXPs6EeK44aC4O5ZDu9K+Pjka7dW8ymgHTE8UUTmz8L7RN8GZUauCkeSMi0HK0YOwY8WWCjKxdRjG9PO4VRFtrnpt5gpbtRoqH7RI9sOBiC4CcChj17Kp6K8Qw6eeiToIsyfMxTxct9ZlBxRjQ0LkWSJywliUpMQ5C9N4V9XaP+wuGCXFuxOUPraXGOIgEfqWiFo5jTuQpOQuLej4UVkHpb7oalfrWJIYTKwJ1lOr3ax2pkvf4SZLrzv9GQz3rzwluIdc\\\\\\\\\\\\\\\/v3y\\\\\\\\\\\\\\\/Y1rXCGu5PgOLZ5XP\\\\\\\\\\\\\\\/VUWl7B2RtGhBoIHFcLTQ9+ZludBst4rsXS4hHuyvLK1i+++2CaTONwNrvI3h8eDSASFcYtu22a1x2eQ0LX1ZW9zkw5TquympbiXwTWqRZNQnZ7Qyp9i2Ze4Dq9XnFLlni3jYgs9alg5UTOoNTTpa2Bn+ARbLEbQGTVMOQ6VBzrHA3mR8VFkpKOJb46J57GCtLwAlVlhgsxua1RnjCQxFnB8Mun00uvyYxrkfxmNrLUlfpSL6+JuNCKDmKttaxps2T13\\\\\\\\\\\\\\\/TNGeozGDiH24x\\\\\\\\\\\\\\\/HbRek6m5yzqQEm9YICY9zkQBmMixoQ3OlFvrgHlo6GTsmH4nuEalVCuMRJ4Q\\\\\\\\\\\\\\\/TTHDkWdhAIbgwyiU7QPmO0X48IZZ2NNlN454mbknUMO\\\\\\\\\\\\\\\/7xZJpmHvHTj4ADtzzO4h7QKaHViGSoZLmvXDtgRiocZGvuADVQOV+Dzc+Yj+EEEWS2KAHCVntM7ovKVFkHz05uY\\\\\\\\\\\\\\\/p9cb+StCP3xPf7A+QDS+91q1K8DtON7wFwu+46RzGXIuo2CsEHKsbuiEZyBj1mWP2iZeK6YqMUzy2pp4Pmb+IdMJbs7JLOSoS8hG186ZTN8C5h1GtreNRms\\\\\\\\\\\\\\\/pE51jPh\\\\\\\\\\\\\\\/I6q2GXei0fMGB0aIVMj61ojrH8yQ89FBZkFELOWIrlo9uXJCyUHC0AJLScaGGddszSFT1EnaaErsvwNblc6GpA9EY6J1K4clTo\\\\\\\\\\\\\\\/Mj52CRTG3UGGkbd08F4YNu0uoxja5nfXsK5Ih79XvWYQ01lsqHNTjGaiXyU4v36trjOF2QZukbRDv4\\\\\\\\\\\\\\\/L20Cv93tKS0UV2G7LO2UqgLMlVdJwVZLdnuqgnwXfzkXLxb9sVV9h9fQ+Vybi69KzrIQQBK4KFhELxJVK9LV7vrb7hPeEU3I1T3r0uijj4GIiIn7DLC4CjDEU9dwVa03bbBeXaYZoFgkvszeorNxC+D8P\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/6lxiQ2RjpykIcSB0U=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022u\\\\\\\\\\\\\\\/56Ay+ulOXqRBDEAhVIdQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00220af843c6bcf07f13291208dde53e67002a2a970d40a8521341b951b8eef5c6bb\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A230.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A230.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0202\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0202\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0202\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}