{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022sPU+KMwQlkFcOxvH6DOEqUWXF40ZRA9mxlqMSRSW0saWimTBhuVq0ShrkSu18PZXVoNMph8gzHFanLkoqTjHAg+ARvODj0PtfSviOPBbBXsafzkOXwT3POzPoaQXT\\\\\\\\\\\\\\\/baBlnoyHtP4VSuq7dx+8s3xEHsi76+Tl1bMpa1EjVpSW28QMYSmidUdJT4SiN0DLK\\\\\\\\\\\\\\\/FV9MlpkAw50q29omHFk9zYUH0pR1powXUPJxDT0S1l1IySiJIOeUd4xgPpv6xpWsCKZYtaOgiccgbQimZQ3+W\\\\\\\\\\\\\\\/H9nVw+rrQwLTwefYk3ttVCuFDHr8n\\\\\\\\\\\\\\\/2XGhGZhogvfeTZ\\\\\\\\\\\\\\\/KrKuZSa6uDVtx2Jii2mSH72WH0oCm\\\\\\\\\\\\\\\/NwjQkfSg5yOSvEvJRUzIyBa3mVUQfiiG6NAwxNSY8JaS7kfVekrcpa1SE1iV1mjTa\\\\\\\\\\\\\\\/ELYQ7lvRZZTYZpQXyqCL4Jeg9OtDGpY00P7ecOL4GgpDmAzJ4MQRzE3cYKudC0ISbJ+FFXtUngBMmBMYDOGX8kSozTObB2PY6s6iIg8HrwxxtTdfumVfNb\\\\\\\\\\\\\\\/roYTq3Cq\\\\\\\\\\\\\\\/pLu7v4fXhK8U8EZ55woAJ5o1oc2\\\\\\\\\\\\\\\/1Zovl79XEdHGaIJZKsEP\\\\\\\\\\\\\\\/DDcCkhKKyjlimELsEVLe+MzgrD+QBqutAL0IwY5ccuILEGgdULXmLz3vPoGmkOBXuxAyHGv8w8YUGBH\\\\\\\\\\\\\\\/8bp5kLlxCvTznZygv2yDTGIPSAsI2r69jv5cauhm34JbJ+VZl6QFRoBJZj8CvD+YbpSQTR4BZfGP8Z5Lgr1Freh9G+EpXNtkbMkG2n3nT6p7m3ccYgHeSAC9eGGieZP+g3posfEOKrCpJXwUHKycNxu3C9zkVx9YvCK4fbfK7pKNIpmlvifE\\\\\\\\\\\\\\\/4s9ftvuUwPLTVaobHG42Ij6PRn1lym5cofE+L3k+obJqs55klq95y3ZtF6ysicPtT5zBaoQYtVARrtDgofd7FpNpPQ+pTYGag8ngv3B0Cf7vnsVAY7kBXApMM2aOAd8JCd6rHh5UsAizToVuWOpXgwXG\\\\\\\\\\\\\\\/jj2drz\\\\\\\\\\\\\\\/VXZluteokGCdkCPNVykoDzWpl1DLwLsH7M9bE7tIlS1SwTP3y\\\\\\\\\\\\\\\/MxLyJKVY6V5kxOMnuRGjdz5XtbGxTNGI6+bm+rPUfvokN60+sW9PaMBmWd8Qi9MSNsxT7mfgUICSgnDuY3bz3V35Cs83WctASVl4jpnlqD1meaD\\\\\\\\\\\\\\\/jWuCqgIj3Zi3vwHC6vY2hfAd7N31aDb\\\\\\\\\\\\\\\/yLsSLWHnxP1QwKn4mpi5BSoKGZLvnVXh14ajynpr6O0rA9sOswdflzmyio57yA+4b3J3so+duFraumI35dUxsWwA6CnOzPazwS3ZiivxvTOK\\\\\\\\\\\\\\\/XjicIGh7fe25\\\\\\\\\\\\\\\/Wbw7s3pa8hM38Q4ir++RmWwIkAG9GlzIesf9b85tVNyDBcFGeShUfzmhEsW\\\\\\\\\\\\\\\/KW0XiSAY1q8pNZVsHYA7djJKF6z+WHDW4nM7ypuD3v3xMgn1NIffedqP1BDGG\\\\\\\\\\\\\\\/J+6oOMXXhXN28GBhTJ4i0hfDHaAESDGu4lbsNZzH+vtyCsNEOax2K1mInBfmikyh7zGbdPAnuuriDXM0HSI59+2j1D0b+BJPZnj8nvgovHUIhh4BF1D1ltrSIndmMdwsMp1CZK2CpLU\\\\\\\\\\\\\\\/TkncOYczHRJpaT2oUnlqgjxsueXvzcNVY1PZhkahylT1riBmyU+jOrnybU87U6f40RVggq2OeKu+jnox8rdgT7BU6z5l35HsLNaxzmcqDAbDDg7ZVjpcQtCIqBDe7uvwY2LTvWF19ie2ZXXAgqi0sPvvIkKzWNlVSH1nj4RJhaxjiHx4Zti4sH\\\\\\\\\\\\\\\/ww2T2Ecbpo8tbEUdAGL2gXGrNmoD4gupyB4cSrZi0opaqPQf+GL+jMa+GnImz7jJ+0ARlJ7QcYFOn37T3WdVJC4eLLtusB3ua4\\\\\\\\\\\\\\\/nCLgbXEGjd5m5drM1066uXkZJKy2WXk1RmpGgc0FtLm3ehn4lUS\\\\\\\\\\\\\\\/6HRvRJ0A0x2UMNy9vo43bgs3CFfGEnTmWGgPG9uBbPI1aINSLj7NVhX8leWZ3\\\\\\\\\\\\\\\/+5JOrNVZjqWqjdbeMALJp\\\\\\\\\\\\\\\/h2dj9CH4vPSX0a4T21v6wT2H1j+m3bLRd4PWITuS2Ba6cB2oiG6sQTdvsqLjOtDn1EUgU+OF2FRpM64yzldc98aUcN\\\\\\\\\\\\\\\/ZE\\\\\\\\\\\\\\\/gyfLh7pZ4OdeRntuK9yDq76fGOFPExLqh\\\\\\\\\\\\\\\/v5WwFVP4a\\\\\\\\\\\\\\\/4NF911++ET9ryhzbOV8l9\\\\\\\\\\\\\\\/Xg4vwZmA1HSBRIdq4Y9lm58IKDTaYIktx\\\\\\\\\\\\\\\/UyCxZ1qrWTKHQ47pdUevmWnSOYJVQOhdtW61NzTw\\\\\\\\\\\\\\\/oMLG+aEEadrQCizSw5TZhUlv6w69wsWd0Mirt7lQE3WhO968xpQ\\\\\\\\\\\\\\\/06QXszA47hL\\\\\\\\\\\\\\\/YnjayK7NOAEElOYikkm7aS5r27czurcV7S5Cs9ss6d9pkOIqUTKM3j6bgsADn\\\\\\\\\\\\\\\/70nBaP1SZgw2EiSr3ayv0ObTjPdJc9\\\\\\\\\\\\\\\/MCjbQqxwG\\\\\\\\\\\\\\\/8uXIpbb9tDxirEcHo1fjb4mw9+eoBWWFuCYDMJjltxs3e2QE0rww7bq5S17PqMN5L4vYtLKywWI3Nu0PAvN2TkP7\\\\\\\\\\\\\\\/5pw7FAGHTwbe40oRbOy6qKsEIQQuAs+al\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/wkOllWDym+g3WYzBZMwRm\\\\\\\\\\\\\\\/7iP7d\\\\\\\\\\\\\\\/nbZA+iqcW\\\\\\\\\\\\\\\/UR65GXdVcgWfbuLpsjcEmXcslE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022el3LmSClgFFcyOHA47A8Fw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00222954ed7687495009a7547d8a2f6385d5018552aba0f7074f2e217f73a577d488\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1369.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1369.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1241\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1241\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1241\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}