{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ZbyVJ9MwHm8iFlSBi08qSsVNw0moLHmUbNY69vE4wAvWRNuJHyaVDtkYr1zI\\\\\\\\\\\\\\\/oRm9mI1jZPuxVgcpzgmoLWDYVrCi353V77gCgavtK3UeSQOT655pAeqwHSOnfPkT8XBfVf+gjo4Sh9fmioOQECaM8xH\\\\\\\\\\\\\\\/Rt0Nb4dpZCERDX+YQCfS\\\\\\\\\\\\\\\/ysIRGePtsoid7BxQCio8O\\\\\\\\\\\\\\\/xDldkbQpN4SgEXI7Tn4JUccf\\\\\\\\\\\\\\\/IEF9Ciw4F9o5Qsv+s2Fr1cUboBpk0gGlz1YPbM28LEp0C8o999+yyQWYtlnDr7pbVhNLGEz96ChmRQr1JjOxBJK27Tpo2HcZhHpnS0ust5DW86lwysVtMvbXUnAITOhI4l1fGEPEKlrmqZAPApLH7PienlkhOlL4k5VM19DgmwqJc3lawNePUUWcmV18FLpNQl29qo9DTaS7eiCbn8F99Oc64pn424DOSWbYf9NQZeVruW11J4B7qEYpevErAaUSU2hftjUTJLlWPEc+OFXEQVXLhJprQ5\\\\\\\\\\\\\\\/hK4qU0GZBvI3yGX0i+XLmvLWtRYxpp9vZssd7NNQ74rzJbO\\\\\\\\\\\\\\\/Xk1cI0jVtrBhauqsqm+fwj3j3KkznJTG3YGvPjEj2eSqm4RXX3wYQgh91vIw5BFvr8UGma97wNAB\\\\\\\\\\\\\\\/yq9BGmSX+kOtZvdThcN1qadkUlCe8kW7FPKFfUsmHI08HXBcCXMUOOZN84Ik9ZIGrGeBpnn10WhKva+Yw\\\\\\\\\\\\\\\/Dejaiq8rQ4JRml954jpJsKXurjv+8J5Mc6DXAm\\\\\\\\\\\\\\\/XSPNuauU+oZCiIQaiVMeUoE\\\\\\\\\\\\\\\/jUZcnOqjHRJaAYOPZdeoN3DtxhiiGWIS7\\\\\\\\\\\\\\\/LAieFunwFzja7VxJRku1tZnbfbsz+NY9RBcVJ6SjO0QMkjlA8KfymDYkxr27hyWFr10HvCLlSgoB8KPg12mj4WGGQoAoxnThBKiUawNneTU\\\\\\\\\\\\\\\/8lBGsc1DeJx9mIlGH6jpgUcSdm5zCLGR4gafOAgzm6owXxiD5vyXfzw4m7NSMpCkdv1Jfafv46whElUYLfKXIlu\\\\\\\\\\\\\\\/Jo4X1KaEwM0+C4cJPoNX5s045GTUj62LyZH67kuUR4JJOpbF79158O+Sj580ZRpSH28OfaCSRzm1RTa24aLCUIBzC4hay9ADs0PI1nzeDVf40WUiTgy9dJKgyGPq1VLFk0o5oUdbr1AsiQWy9YWCpQMoXtP0o3giXr7XhW4jZ4hyLQEOihlgPTXcpNJ1q4x3p6gPEJc9HUNzAvpQFUFJUGVQLXBydu9ylXXRs6FnDNr3EX23tv4t05A6q\\\\\\\\\\\\\\\/N6olrpCHlCPouE0yAjOzoo7+vtCQyhxhzqIzsV3pfFRV9yK90J8ivIHLMlimhjHjHJWeLdbBm2J4uuSxL8M2lgmlQFi6ThunvLeriaOWYwhebZGaC+K+TmmZ+8l8iBbCVoyaaWeASW9UiWf3PXitDkFpThK5k9bR5zcyMDg+va4Funh9eUZzQyFONErr\\\\\\\\\\\\\\\/vL1lsTkkta+DG95fIHtw8MhYH+2B7X+4jn2KbeBjL7UdoSKqYmCeU4wptGrLj8UtBwFJ3NjQhVipZ7x\\\\\\\\\\\\\\\/RS0KXObKK3UPgvvVbqMWJRKgMbZ9T16sl51HzVoEebrAjQ2jcchyVWqAQXAgjZ0YlXgX5UkTTuGosiNcpHeQQtwIBRS2aoGwF8wuaNcK8ZzWA05IzRQJ1zc7YlvsaNwulQXTHFxMKKZ83IAodiqN91LEfHLy6IOiUac8oOvDDQJAu392JgIw91WyTkaNIqplQ7Jey8MN9vUYy3LbEfnK62O9pz7\\\\\\\\\\\\\\\/DUp4VbYqO\\\\\\\\\\\\\\\/H6eAwL54BtzqKlTMc0vlha+qkzaDKwZ\\\\\\\\\\\\\\\/pjk12lfGyIVKGivpiiq\\\\\\\\\\\\\\\/niaSRpWOSIErEUVZA3bpIKYfKcCIA1pO6uTz7mvuzgL\\\\\\\\\\\\\\\/MkrhkKzgM5dqVrSvzkUWjSog9jcwnDpfD9a7RUdAbCwKDqXycHT2tz4vpo\\\\\\\\\\\\\\\/lopeJ\\\\\\\\\\\\\\\/RpYD+sSRyaLgBGykq7Hp+puYpoBzZLWFIdGxDRRSN9aXtLJg1lqaHTB\\\\\\\\\\\\\\\/5K0DA5mLdoTXAI5Ueec9A5fEe758Ark0cQDo7Xp7MBJ5ro3+cy221jUgDKHNh1LkJmrCIy3rgcBC30gjMCMKUCcBG0PNGJBWxUhoH54PcKsaC+Q\\\\\\\\\\\\\\\/zCi8qxNUkpBwNUUI3RCVixFmM03CJFh3aofyP9eGmvy0TzaXiLml\\\\\\\\\\\\\\\/KXoUCxrbDy6LpHJ2c8pxfpnfrrM+dtYf2xEZm9nYlDdSXcSTA71wpkIcELiTUzGhWHveC5zi2aoVhA4Bq0tIRiRUObqDGcSvviLxEud2Muu62wkd2uW7vfSAGYW+JT7DKTAKO7hcSpuJYV5yw2D7SjNzawR0c8CTu8gqHJYLu4lbU9sVhFAQLrS0BPjwp1tNtjpb5oOh5eSpKJIulICILtDmZo93feGdO0hRIu6\\\\\\\\\\\\\\\/ERpqhrLzOa9S+5WRIbVYjl29zfOSqJA8zInFuOmPFHvR8SRsYK8FdhnSVCoWro90mT+kBC4MDOgdc0zdJfLyR5zZFANT7BhOEfcRwYir0OBT3xj8GzS4Io3\\\\\\\\\\\\\\\/Jw0stpqtuqIFydjuGsOCdMsSVGW3885Vf6xozmU3DRljZk6j6bSCSyI2PLpgDPS53g+R7RmQEFE6azNeSrx5MyXPAgCK5VVQYHmH5U1zWYiHewlM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022az8iHQ3tcOI8H1VvEpiNyg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b6cad812845319288ba5cdb8a79d34f715ebaa5c1698a49235a822d244a0ad1c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A81.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A81.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0071\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0071\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0071\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}