{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022q7n9KGWleasDtguAea7GCQzvoBbSOy6qANjf+TzOg0P693kHQupujnmTgkQeAUomGZHZGBE2ob8kqI3BkcLVSMFKvRrZRQ3s3uWRXEOskUYtfogxbC8tYTNM6369GJgAlkid7Un\\\\\\\\\\\\\\\/eNPt660TFS0ulGeydROU6u2AvWXH+SKSmDVvdB7NW9Ekwow8eljj1F\\\\\\\\\\\\\\\/yxszDdVEfHM8gf6EvTgzyHc5Yqtz8Co9FVyD+qIFL3FCRI+V66BhFRaH6T3EqNpes+FvS2sBbwWibw9lqsVJQu2B0wSCe1LdOkMW9Bza40fa18DqQwOOlGnM1EyjYbxfVGjP3hLa6XvU+WqKUfx1hEsunfpeDK2iotxMgwNhJz2XqlT6sSOYHINMbtuCIubgCW4gtz78xKAklcqDVoODF+uj21g6uqEqotaMB2w2YBNEbFXnqhpfYLI4YK487iH70z8cqjGldZ9DQfsHchFmEJIkoeHNqj86cZEYzGQPG4ykeVo4HLZEUPFmET\\\\\\\\\\\\\\\/JHRoRxmvxG7C7zvLvnLDlOT+sLllA4yIx14hqEQEzuCxHAb\\\\\\\\\\\\\\\/3xLpyOkrsNiNhrpO\\\\\\\\\\\\\\\/UcnPGb32c4tyPxY2asdOPaqNKkRKZklVjOf6h2TskJOyxMNonM4cujpfSDqPmCN+lyov2mrb8cjysc0TWKHxEMTJ+ZYriEwS92z\\\\\\\\\\\\\\\/8HnOgHQwyy0gMzWhiqsZF2sg1PXXQqEDstxyLzPLHYPzFwDomGhPAxihnJehSQt9VV+CxPsPsI0ze+VZvycpTrny81Ug0kNnPjCeRv7O7wLJolSs3pmAZyFCRUyaKWwdOiroHZfqXBw5kJHFFoU9sd\\\\\\\\\\\\\\\/dPMYPW\\\\\\\\\\\\\\\/+ExtKQ6v5dY0zJuGQoZIGdNold\\\\\\\\\\\\\\\/WTPJE4ByP3nKSQ3cfp1Z6oawvFzAX\\\\\\\\\\\\\\\/xIn1fbEJdYIVQlnIAHyx9yjwvYdlFRzRYUVwjqM5bvFb8FVW4VizMwOf4SCWxt6i7T+pYWxomyh5WxTeoO6H7NCwggW0Tt9V0UJunagpJcQkZeuTMd7POlDDJbAj6kvvNHIeRo3M+R0FQKKkKT0nO5x5g\\\\\\\\\\\\\\\/3AzRRwuZXcQ9pFUZBNrupMplQDVrG42nhoxkJV1GswjUa9Me\\\\\\\\\\\\\\\/8+TZCisGAF681cNogOpEQepXc3AOlhTlIOftMun+a09X+cy+HgV+6LvXs3Dj+zSAwEX3Z2PIYpAW4A94GO8DTxHECiMK+ijfCOKakph2ayRF2MgXpjo1eNHfiN7SBOTEXJCWFWB5JZXw0B+vjhIFTmiGmJz\\\\\\\\\\\\\\\/BtzJqjZ91pcjgnAXw\\\\\\\\\\\\\\\/o9HgYlQZK5aIxUwR+njxlKWkVf1pfwaFnOpj6N856ArsxLHbUonkVP3rN0vfh58qlXDcYn0wv3FYYLxkLUYViQf2KP+Ev9IETUGT3gQM3f3AtsfuZHV7oybFKZKgizUf2oM6puMZbeCUv++mbFICTqhnMNnoURl5hoctydUuhjXyrF9WhKFz+6gDI\\\\\\\\\\\\\\\/MXd+PEgLDAWxUCmGC24xp6uXDA1uRIOgZNA2XPz+rdkbjlT3LbSlDzm\\\\\\\\\\\\\\\/ZVj0GUkmsH\\\\\\\\\\\\\\\/rA2Guxit1nZ5DyolQz5i\\\\\\\\\\\\\\\/IjRMBKQddmn6bZb7VzMfVrrsyvVHDeXsx0I3S4SQQgyUGIk39tht7BwEE4X6qxppnVW\\\\\\\\\\\\\\\/sXOLuqkUQa9Zvic69XrorMWsQNgd9udgWaAOlUGdfrBEH03C2qHncVxC5ArpDBmcC8Hn2DYwh0WJz7tlIfITpEjCWo6+aER0HrE+kPjr4sJ12KvspzSuszCn1SLRclGeXe3Rx2XVVZ3y6AmyTpHklOkRDfk25AlyiA+EjEqchTn531e9xAfyeOR6eSVWdhfDp5qzQB1gqsAx2cPcNOgJixOVygDEdl1FMiH552oF3NCxuqN5iddayg95GUaLjPOPV7P0gkEYXhN+B\\\\\\\\\\\\\\\/Zm34sNo5cfc3cUV9KWuEEKqBFzd3iFRY7bHPySnmAitrAZ8KBuaC1TF2Ynkl8RTJREEPsa\\\\\\\\\\\\\\\/qFTOktPtCUfPGCLxPOuRRmZPKZctWhXp1q7IZDA8F3j3RzhlrneNu60GNEAi13fh0Qmr2p7fayQzovDcWqnXV31Vh0XCvj+Gm\\\\\\\\\\\\\\\/MzMtEzu8LgdWUtu5ejK3QrwuPcz1gtN5SWKiBMioIi6xTFvbid0U+t\\\\\\\\\\\\\\\/8AD+hCODOjVFURG1NqDHYNEd0RnixKNTsPwRgHwWYnPTz7lfrfRqXjccS4w3p2AnwBCUjQlViO8mfj04n2itDwe1gyggNjqGcC\\\\\\\\\\\\\\\/mDKZw4R8TMX\\\\\\\\\\\\\\\/V2Uuuc2sy\\\\\\\\\\\\\\\/o+Ai84p9vKxOFzZKBMF+oyLKpSuUZG2f+PriAaRiUKr4FtBZQgM9muqOazfycoAm3Z79AlpJ0KPbzTnJW7dv6HFa3UyFT1Qz33AQ1PrgrbBntuRv77Uy45SEra1LcB1ZdrvSqYEAJAyg38c5SfuDYYW\\\\\\\\\\\\\\\/0Iln9fIAnPfuuBaBCc89xUJNfz6shWsxGpeHmVwM1ZRKzgyDXMB9Swuxg1I3gBbR0IaMerXRPgo1fp40GxnJlN\\\\\\\\\\\\\\\/1hwIR3NWEtql+MdzM6lfb8EteK9TeS\\\\\\\\\\\\\\\/lcMZLFXnhhwwJhlwrDx0BE1ZzqTSTIN8kQhZP7q2Ylt+LXd1q4bFUH9V5LmFRLhDBhwGm64Y95f2ZYx6UoLZatwT2X\\\\\\\\\\\\\\\/y8HctTUJxqp0lE3ogvFl6s=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022GhYV0fgNNiPxiPTIvnYhHw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022efdb41785e74ebe47f533fbdd87ad0b3a8328b03c6a1f3a1273244b2c098160c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1613.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1613.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1450\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1450\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1450\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}