{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022sKbHuMwvVi1yNzkuSI5XZCKDavX403yJ7iNAJTX9eJOYeSBVC21fxXEPFHWri9x1ARcOOCJHmZ+7\\\\\\\\\\\\\\\/trEHyfRrzgys7\\\\\\\\\\\\\\\/n0EZt1hgVi4mVhNMTHFQaDqOYuEbJtiSCYa8\\\\\\\\\\\\\\\/VA2PmH0\\\\\\\\\\\\\\\/YvT17CBsCxRXUtME5zAuWzF4ZUDl0i4xmEvB7p5LkiDLhU2D35ndKgpPfsmyLa2nS7UGUJSpBDq\\\\\\\\\\\\\\\/KtH\\\\\\\\\\\\\\\/hZxRMWtMGHd3nXnu4i\\\\\\\\\\\\\\\/5n8R4CGkou4ma4yN\\\\\\\\\\\\\\\/YZF6OL60yKWSzkjhxYGaoj4mypfHugimU3yFwRErx1MPMNwQL4Jq1mM2qV1u50m04uDrNxsTGdEJ5i1WcjzOYPCHlBbS5AXfwCFQGguFyHX5x7bU0Y7JHhGfRUSoftOBzRY53XcKWLa8z9O100Q+ZCtjeL6AslVG0\\\\\\\\\\\\\\\/meNoiUszgZQwD1UPU5O4DcmRVglXBx1E3k3Pjo9qFbUCdggiHSPRFGD3IdTDFnvPNRcKdWOIWFNTY+ylwPz\\\\\\\\\\\\\\\/KIZfKMnYucpTRK51dX8A6FXDbc6bAz1wqwdxh6vlkNEVLmrd01nY0jEBB0NSJ+y8H68xDum0iDnzuaRA9mxmNgd66epd7ctTgvMArDQnM73nHmNirHkwVQsi9sZP1I+6\\\\\\\\\\\\\\\/vFwra+LbrnwThGqgeGujQqus4NOohoyDAm14o+ClGtsCtY1Eak+E+m+6n8BLPmh64ef6QgbkqVgZmOi32TWm3KRz1JuwvAHZRgw1ND2b3qAZLpj09t7BNgWRH4h\\\\\\\\\\\\\\\/W0jLQD+9xtSC\\\\\\\\\\\\\\\/U7XAYJvvzgZw\\\\\\\\\\\\\\\/tjucpog6Ez+uz8pvG8oyuYE29+recwBKLCcGKrzS50QX0j8g6PqMvLtr65csjtKwC7WdJy4hcpIL2u67goe6d19gEy4BAG4kAskeCl01R4E9EtprSxEoJ0HKG5e29Ls+RshPMhShKGfhyXX7r9lXZWsZuIGayAxay64vZZqeUM5MaT4j50XiBnCP+I4r4ZyYX7uxI5cMroCfuwjtcRRd4FRrRzA1gTUtPc34vP4uiIC4HS23Jqefuq1zPP04LcFk5nvC4lbJu07bwpkful5zVMmGwkanl85Ra0OlUpAnX2fKJjRP5Wu1tOnmedBPGXGwKYekyHF4EEqc3aXoUNfXmw0Ok52ePr6gfk8nsqekzdqw5Sswm7n5mmKoP6c7uBs7iqnqvdHHyf0Z+QAZNW3C5Irg4tzVVu+AcBfH60MfmGco+2REWZNa\\\\\\\\\\\\\\\/eBEbI4wGv5LVbBVXMh2eb1GwtrTzaBvIndL9blnLJRY4H47WLNW8dPIoBkN530jY06fgjUXolXYw4S5aR+s0mtkKg9nfGOmEIKmmFxG3UwRj7YJORX3kwRFoUkKjlqnpZwarhcu0QBWzLRXRjk0cDPgdJZDqOG32knl5Z\\\\\\\\\\\\\\\/DBmnatXsflnRzBwLwMUN29pCt2h5ShXt0AyhPHFJWD80M3t3Hm5Yo8thDyKSCexhAaqwcdbi2K4djJxAB\\\\\\\\\\\\\\\/Jn7TWp1b3ne38163oqXklTjfQ3+7P4+AFWnyq13xK80FU1APGEIps9FPwfRWXypXiyuUVdFzmm5mxxeYU04Rbvzq8mnXaX48Yua9unORCcpaIWgDbyYCFGKVlsqyAq5Bogw3O8VaNfUa38yEdPdww94FtOjsamvWEvyKdUVwpCQ8BaJC\\\\\\\\\\\\\\\/HftGuiNnSJFmBOwteP6kEvSu0iB79\\\\\\\\\\\\\\\/jIiCV\\\\\\\\\\\\\\\/ci6dwT1YwNSDzmvlV1DxTsVuLJEEwUKKJlwQ+iKqXEEXzp4XM\\\\\\\\\\\\\\\/6sSlp9LhNbBn98yfAezYMzaDGJ5FjjdMEOXNLiSIp5PQInz42MqpD4BZ8FAB1savcvLXRxBApUscKUX6yX7wOrKxYbJALOYbdStHvn+j\\\\\\\\\\\\\\\/ymGtdZibPVCKEMHHXTqBP4FBYMlkwneivgkVGJIxNysivUNtNymQaMLniFE1oW3xMsdRd9ydPmRu7cyhUEm6pgyGBoJARUiSseH+hxX47F0SfHNKTli00YxjGc5jjmnzPXBXjIycORROmHJ\\\\\\\\\\\\\\\/46ykyG3zX8NipmUoVrqkEYwMfj\\\\\\\\\\\\\\\/ztPqlgvgXEthOShZu3h84mCA9yYU4SeKLiFJQlS6JdJ4dK9pms\\\\\\\\\\\\\\\/zNcd5wBAQjbcZJIBQY15uObPuqyz3RcfMeG2gNm\\\\\\\\\\\\\\\/dA3MG\\\\\\\\\\\\\\\/ud5tXBKlHqJGPRTsIljd4DA7MtsmyL0nWzo8VauU9A8pGgpY0H\\\\\\\\\\\\\\\/wI\\\\\\\\\\\\\\\/LsVrhAtTYq5VLpl5oEUHxvWfgTeBwbp64CInIYHq1uzkPnAvwUhpUq3NU+QYHdFsPXin9ZHRGj+cl7Un+w+IUux22S\\\\\\\\\\\\\\\/AvNfDrbcNfum+92fx48P1ApEt0Hnsg++2stNXKrSAmc6sUG400saB6bsGDttKIrZJeINfDohXvY5aA2rAQrYsH0Ov4MYz0+6gc9uEvht0pSTXtqt00bqJ0UUn2ks3TWOT7LbXMTcWA\\\\\\\\\\\\\\\/KUC\\\\\\\\\\\\\\\/kIJcHsmgCF6JhgfuHrJrBULhsz1ztUI6OByrwO6ueisZwrtNQRCAFPh5s+DGq2ISG+3e4LAiLLSbqqugN\\\\\\\\\\\\\\\/GEgyeqE283DtfZtdqAEdJcJscq8oPkP174UFrzFlJCaxkeqAR+rOGNvEiqrDdJZqdsaXWg858GqbIvC7UPLJPjxarfBraXJEr6qhR9+pC66FPMwl5w0PjUnk0r1zJwvIkVMSR9g=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022wJh6MM4bkTqKhl13RK2C5Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228acfbbb3451e68d3386390548dc1cb8ff4425f656a4d6a004ac604d248e8d66f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A739.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A739.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0647\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0647\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0647\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}