{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022oXtcXHd67TKXYqQPrbOy57lM\\\\\\\\\\\\\\\/137kaI\\\\\\\\\\\\\\\/Ez5syxEeHoWSma+nHbqU86fWRhHEhD+xseydvmzBIGvYJ5SpwLhcCF\\\\\\\\\\\\\\\/hbbs3wTQAqTMCQ6\\\\\\\\\\\\\\\/Evj04x\\\\\\\\\\\\\\\/gvft3tz7kZi0mJmY4HVo7CeOVwlcsbeMQ0KnTpFJ72Ep9\\\\\\\\\\\\\\\/KAeon7Uc2cn5NDtAHL2bZnmxcKUBzPDsa2l9Hl3FPzhqAfxjJsCkeaZJAJa4J\\\\\\\\\\\\\\\/roIq5ZpFME7K7jhvqQiFIrxKlJXZmrkWF\\\\\\\\\\\\\\\/6bIo0ZUTrFp1ZoAf9V4\\\\\\\\\\\\\\\/pHvY9JLPE9jf1wPcK75T0e3poiRJoDWlM7\\\\\\\\\\\\\\\/avpx8F9WzF8Kw16nU0we8hBZWaOqvNjWtMju1YCh692B9hS5Cgm9dPuRHl93hF5n9WvhCeg7HypEJujkqPbw\\\\\\\\\\\\\\\/BVqsrjnV2w6KpGxUqgvH8gP\\\\\\\\\\\\\\\/FaVyNa02jXeSHUK9jVGYfgIltt7FKNodCi7VDC5Cg9Fl3yBrT2qUXTWYqQisgzrx59FowPaX2WL2a04EHrdgVp8Man1MIGbbM1K37YsW7nEhtqr\\\\\\\\\\\\\\\/eG2lK2Y51ajU\\\\\\\\\\\\\\\/LUTf1d0BtIhHZBob7Ch1g4biVzWUnetNNq0tBefeGIOUFMmvfDENb7HNYiM0Qdxq3fR1APbof+DrRTnpfwrs1gJ6XCLL950na+1kDrmcEBC4wO0AzBcLPiWQ7TIbjS+CtFrxDiAgZJMTUTVNq0tj8f9\\\\\\\\\\\\\\\/NgdinJmY4so9so4b1LtFzzzqvoZ4vIIKnTm+1WBfTCmU04ZFIGHHNRx2wQdQAdr3AIQtg7++Mb\\\\\\\\\\\\\\\/B4Q2raw7rZsJap9QTHUl7csx6x5HdGBCFqswt5YipMOnBPl71CdnM6e7XQiUwqT275Guz\\\\\\\\\\\\\\\/sGHuHpHKJfYPGnv5NF7yky8iPKRk3ZUCNnnL+rCL6B3pH8G\\\\\\\\\\\\\\\/D7Ya5sV41Haxs3FP1MkBL2kjhGyjk\\\\\\\\\\\\\\\/S40WF\\\\\\\\\\\\\\\/C7JUyL\\\\\\\\\\\\\\\/dnQgQ3Pl9zLSY2G7M\\\\\\\\\\\\\\\/+3BcKnBSgxykoI4DpiTqdghNiC1LEhjqFGHhuSHI1Q9\\\\\\\\\\\\\\\/NYQ9wbQBjBubzmU7U+iHNg7zNcK8PnpxNORI4MPV5jMB9a0MVoWat6pdWCd0GY\\\\\\\\\\\\\\\/jy\\\\\\\\\\\\\\\/jRXolp9oNzc7CvGSrOa\\\\\\\\\\\\\\\/2uSYMXvELWgXj+zLjZx3GZkVyEX1DjoPxr09mYIo1nLkXclc7fMszXthyGEzQGWopBv0rQVhYd3YFlEYmalls3X5QtEZOaBmOZlMmlefjZqO8w3r2gmeStatwaqVhF8dKYWgydUjVxftrtUGhYTf\\\\\\\\\\\\\\\/lOTnIMm7wv8aPKgPCxw59SkhOxazYpHzyUyRsWheVVrgqAYKOkrPVVu1k29iMzDXFvFNA4m11hyIsTaE1inrMSaQDCxP20FagmOJVdfLlAwyTndVXxlT4rnwT99NDDusNWBKJgMBKquwrJ8YH7Kf8bpOt4apz5GEe7WxbT\\\\\\\\\\\\\\\/dU+IC+ZaplHR4MTAcTgWPuADLg2qKWMiUe5cKkEC+VIQDz5JNxYohie6XmU8mt5PfPUn2z1haBkord0wdjgs3SF1ReoKclcfIWrgkflDC9SM2FAqoUO2tm5Q+Y9fjAsW3+QtCGYnZHOOVh6PNuO38nmAE0wuIw3TmTH1FpGPMQC75RfeJfnU9uK6EJtxnveEM9895bVcUQjcWN3bjjBGYIZwlli6ZkbV2IzdPGY8j5BFws7LbUCeDfOlSwIC+MyJwgqQl8pnRgQBS88aK10kydaC2UHrss77w3Yjm4ne4X9Q2WVa\\\\\\\\\\\\\\\/pyRslI3jQX598vbtLtjQRRKl3egx0KFrp9GNO0VDI50ld4Ps6gIMMvdkXynyQq6C9UMFc7mG+sw\\\\\\\\\\\\\\\/i+9dnDP5L1A3qRJHgbYp55KYp126BJp6ztimWk2\\\\\\\\\\\\\\\/Sbiiafb8XfM3\\\\\\\\\\\\\\\/GKttiMxRPeHXy9ghkgAKNeMBEfwgJ+p9B2s66iQUYMB+OUVz6bmZAF0Xva\\\\\\\\\\\\\\\/2cRAXeKkjnQ1Uf3\\\\\\\\\\\\\\\/o013q\\\\\\\\\\\\\\\/H+uh4Cy2DHmRmYknG+oTQkD+5ko9rfEE1yBK6fbPc2ulF3m3A\\\\\\\\\\\\\\\/SB\\\\\\\\\\\\\\\/bXzHjk8BSqzUBgZf6N7SmdqLQyafyOAOsJop5qPr+VVPXB4xdKdIXjJTRfqGkB+PhtY1sVBguqejktigVWbAjmIP9Pqc13tJAvrcH7XogxIUSLx+LrccB2D3+2lyAXgWG8Lqi9f\\\\\\\\\\\\\\\/QqlmBeuviDf9VrKSUk2Hg0qtlgDuscN06+MCl2W1FyOUEcwLjaOjOTA7vpGTWeILSLPtjPGaH7z2yWx+DmQWgQFXPzis+68lVDH9O\\\\\\\\\\\\\\\/NQ0zuXY138i0UFwBEsAKMr83WQcnxIFkdvzqedIbAYPk24I1zpJBllTcPpG2gAw\\\\\\\\\\\\\\\/l4pyrckQ53+Fv7YO3+uAMCTXhTtQhkpTjbZfzZey1J4qg8TbnbY2QzECMGZtWWSSKS31XCvRJ+OIsv1LnB6l4DxGXu2kK4TSq0bV8Sedhc5N1EqnJiCOvVzHKcGbCJTla0D7TtpKSkpxFm6B1ekDVJgwiIbcE2IJVxO1ZemGOT+AElbWiF4OU0ygZsXchox2itn\\\\\\\\\\\\\\\/WppaARVtzniVg1uE3367LweX1mU3l0s1JwuK0VTKlW8fWDLel27DPEWyFM1cqXhycbI7Nufp8pemVQ8Zw306HnFF0SrWQZaRU8MbtvqHPME9Ho5PLh9Tjj9DpzHpYyynuFG\\\\\\\\\\\\\\\/IAAue4piO0ko=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022q+Cmd8WmE5rpc6Yp6rXDiw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022aa4b114ddaa6eb34a4660d626cbee0be14949926858e800386d585433ecc6324\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1160.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1160.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1053\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1053\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1053\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}