{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022esqcDx1Hd+3j4dPFa6JDsixiBFt\\\\\\\\\\\\\\\/2C5w8GSpjbLPnS4W7lcRRhJLYvor+9hHBYDbBwrinH\\\\\\\\\\\\\\\/5l9qp8AGDfvtXiUViFBxL7RfqURANjcus+0aw3g5CImfIUSIAdUxvfueB4A8bcnFIqpLdCrw0LunXrQifobpABekP6w3ryMTM2uTNsuMVFH4PYS6vKnjULv\\\\\\\\\\\\\\\/9XNgZdsbITYYBfHY8VjQN81FwJ5SCITrqGtAi6Bot8HqPf+PqJYbmwXVRqLyaZqP+xmCCjWw6yZS1LJiHTVgq9kb+NU7KXE4YL3mLFm+ez9r3z7c3dUPMmAlAVHTeJc6X\\\\\\\\\\\\\\\/hIONYGp+MWtzrrJa\\\\\\\\\\\\\\\/UYYvx6HEJ8YX+T+grMFrTNYXnbXkTzFHX6wlJGSlkoo3dy6LoJA4tSlHD\\\\\\\\\\\\\\\/53eqm+Qtg3Cw+TzCQY3yRDVAh5cg+qnnJ4nt5eGWrsi0lEYz5\\\\\\\\\\\\\\\/x1LfnykpU8u2ruPbOGh49\\\\\\\\\\\\\\\/cMc2PmPXn62iVkhw2fm067Ll80MdNfCGJX9AF73zdIlGlLRp8990ROGBsiUE6yjTZg46KMnc8sFldZrqeaJjG\\\\\\\\\\\\\\\/DklWFv6mpUovnOPBWpTEmu4ji7cBBDAgOf7aecclALwXpJkFDpmnLVyxWarsV6C6NXQJnsOYr+WVRaL8MQflUUSz4tlNuvmUeLdMQQ\\\\\\\\\\\\\\\/JExlt9E1qRGdaqSq7JmhSvW4dat1CjHPuoz+ZISQDxQs0f3sZVgaebHLJ6vz1wmO+j6mELKHr+wGN1DPEMWALubQUO+wfrw7eQjmry5FLvWdqCiFsebWreCRmDkMzRyOO4t0myoXBKQjHEpP7CXWRd6b20gtChwKj4XZqg\\\\\\\\\\\\\\\/p6PaTaitqSndy3MVdRYb16giG83Sl9lpRbFske6+Ulv5pTs0anu48fkSN\\\\\\\\\\\\\\\/xYvPzf6IfLMuOxXlbFlb+Izj0ueynbRQGHjPNXu4UnaLTtJEAR+lTUP6sjmtfUV4x4v\\\\\\\\\\\\\\\/f8C+o5BQ3vR4KP6VoNmovUhcYKMH+njiMl8AZ5o62bgXlDXiw3eXGEob7zysOCrlDE65A7z55CxtoYNNm\\\\\\\\\\\\\\\/3hfokuRcBFbhBWn77O\\\\\\\\\\\\\\\/6zjruU4YGmMO6lz87sOa\\\\\\\\\\\\\\\/6lVaB3gyTm1CD0vl4SQI546SF5e9yArNOM6PC+LQ05oeMC7rh5v2x8U2U08Z1KFwd0SaJsm8T1wRqvOiHXzA\\\\\\\\\\\\\\\/qnssES5+QDmVfvjHITPUfic7wmICtyLFQfZrUd+qzJQnJyPWbn9ahP8KWkdt02pnB2YjeXtCIhDI\\\\\\\\\\\\\\\/8ap8hxPhyKhzM5B3FmiH0YCDAjAOnoL6bJpd1MDPJvdKj\\\\\\\\\\\\\\\/WDJjqxm0X6NeS7xUm9DPBO355Uqy13yMgvxKFATWdaYwODse0mbdumuaKvj+Gdh7ywLpXxNwnEHesKDN3ySbP+HcFYvbNo5kBaFMd\\\\\\\\\\\\\\\/pWQ1r+tZJ5ZxA1AFIVpwIHrXRMh0\\\\\\\\\\\\\\\/G25sGWaOfxhjveoPywLUhG5+P7xbyk8Tog414gESqEFCL9BhCIu4MLCgBPdM76FXRFYBHXas0zRH6DxmXsYz4EooBsu1U67E+lNgrFmpEkk3F9W4Mhf8Y+z6ItfTCA8bkf1gAl57IKMmE68UkMwizgfsMuS1+Vr10KCb\\\\\\\\\\\\\\\/S6XbUO70pqFiMk1FvXrMcgzlSh\\\\\\\\\\\\\\\/RKcKAhD23Bur9AqI\\\\\\\\\\\\\\\/3EajzEcBifikUbh1QHdaAxWO\\\\\\\\\\\\\\\/futzyTpAgaSevsnpyhIkFrFmEv9YClVCOEGEmgCI4Y\\\\\\\\\\\\\\\/f8o3UlT6oOfIIRbDuvaSRpwyTPIV4c4Pbmh4QQ8Uv+E38wV6uGgWXwJ9lgM+wWTutUt7G+Kx+baEHW42SS1PZU4sZvHPQlpT5W6q+HgO8IImLyyNbL+cIppfMpiv\\\\\\\\\\\\\\\/hzUOgrWUOHg6tOdI+fTzKTQYxzHTaj4ej2ydCNN4r9Ykhut0PsmAqe3VZGoskeFLaqVEUkO+Z4awCreIUSbD8uf2FROaEJi\\\\\\\\\\\\\\\/qyZbg5L4tVxDCyJ+Y+hvnr5MBLgDiUUY9jlUM\\\\\\\\\\\\\\\/gUw25x\\\\\\\\\\\\\\\/ax+Yuq0hDEqe7UI8w+R5kXxJmJVauMZo9\\\\\\\\\\\\\\\/7GW5Tb7y3uVBuK9q2vftT1FDlIX5Tc4eKxO\\\\\\\\\\\\\\\/rwJKRuXEQgOjD3kN60kU9rul1lakQA4I6rkcG0b8jBvgAhJWj+TdiMQK2BfJuCCAF1H+OAxk6aiOUvZAuYlsVjo2WPLGZRF6NFd9OugIC3tyi876jnmijbIgnMsbjn1Zl8nqx3fmL2PGEtbDHjq79SpYV2fzLbjwf3Hyc7B1YuPMhsAZmsLV7wTeZDKmT7j4jZorOUTZTL8bYvybVQpb26bAUzKDhwJ8OlBZ5JmGE\\\\\\\\\\\\\\\/yT7AAID\\\\\\\\\\\\\\\/bNvaXknjURMhOonhuGWtM1ZBTFGBnKNAVQWFkbIOgaXGg3XODD7zJR7mB8Sj1ZJ5r+w4BuFqqVwXfrCspOmq5hv6o0c4pXE2Sgfn1B5zjgQJAJQZhMZz\\\\\\\\\\\\\\\/42uYGjXQF32lr4BRCho+HRV8ymwEXTKV8vjIlVND1TABi\\\\\\\\\\\\\\\/felKLxUjp6zTR34MYCLdRUGvfiOdjpZQIjtbCT2r0iij6xWu5rSRcBVvu11jbAzXNUrqpWb1UkcrAH7pJiQ2Nf5sc4dy2ptIGvlJw8wK1FA3rt8wpqG1C5q7iOUelrKneEllUkLkPyavlYdx36Qg8UdpppNPkIj8eeEP4dXkqJX2qo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022wVx8JfUH6uUyplyN+xzUDg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00224c157e37ffcc9822072ca0820057c5060694fa10ea077789dabf06c3b114a7f4\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1157.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1157.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1050\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1050\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1050\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}