{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00227XNqZ6OauOnFdpoSMlWSM2i1yj5YOGmgDgUOBueXhhsnlJRSdDF87irKtQNJV3Ak85UnA79d7gif00DptkGNWZJZ4zkNxJs\\\\\\\\\\\\\\\/6Gtn0w1IcIrgqJCsQO29NAX99LkW9m\\\\\\\\\\\\\\\/RD8sSsiaR6Ak+3XMjgHm+Jtj7Nqh8iXzFueALs\\\\\\\\\\\\\\\/NFdxjrSUq\\\\\\\\\\\\\\\/6IY5orEIqBhaZ999RKNpISWBDGaUf2IhJvGCufprKp5Po\\\\\\\\\\\\\\\/o47Dzv6En5CxCGtdrZiwwsuWwv5oyFVuyqr03rfY9eT\\\\\\\\\\\\\\\/H+bWmrp5AHhfj36GtzSUdoPt\\\\\\\\\\\\\\\/OuhXd1638fBbtHzUY7T03bGYPFIbsl5xZ7Roc3txLsSAKtlMTJAoDo19vwb+m7CYZekcl3K9lC+YTS+Rtpu1GoRUEw7fG1+igjoJgJWUb\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/jdjY4drjkF2Lf9X\\\\\\\\\\\\\\\/3KzUs1alOTshpFUlP1zGKVFYouYHwaVr00SnM43qnyMwofSg+qvad2S8EAjE1pb4EJnWX6p5oAKZPFDxnqCfo30qjQsJUx9x7bKfH01Or8loNZTMEXFv1l0Gz0wDg62D3gnV2aWGHQc80QD5XhZOxSFNQI2oryZuj\\\\\\\\\\\\\\\/Rr8NQfi8S8u73ixzObpYF5qCTvdgVLDXgLNX7xgZIOyl14ISpTJR0UjH3ysjLNFu+GkrIEm8E9iGjXWtdGnAbCHMZM6HiUzG\\\\\\\\\\\\\\\/iO64ojzFTmZR2N5EjQQNRl9d7wDzOc4bTEHioQXPbqLb4elOLycwcVTnxhAn1OdqliCl2ZVH4dwt6uA9GfUj0kOGAv1WGwAaNL5LEujZFL4NQ5CyeZaGb8\\\\\\\\\\\\\\\/GxTIIFFeGIZ\\\\\\\\\\\\\\\/rQ\\\\\\\\\\\\\\\/pth4Cy2K5XusNn7XMvFRm0HDJwOXSiJMYkFy0H\\\\\\\\\\\\\\\/7hD0y1XainjpXO6OASDQz9rKk1IfdUrLy3rxSGQYAzt4UvfzeXxpB7uMEN6Rxt9Yu67AHbrg7j+WXDUqah0BsVx5iXo5EyyxiSsJ2HiA2JeVnxhOeM58JwqF71pzTtc0RUyiv8hXP1YyRAnJ9hTwRO8ejQPsSNpHLseep3CwJzLbONDSCb\\\\\\\\\\\\\\\/J0J2EVIpJAVvkTy2QUWWI\\\\\\\\\\\\\\\/TPK2xuQT4MWSECt0Ra6K\\\\\\\\\\\\\\\/9QtWLzBHn1J5239K8O42Oio4tDaJw0xVi6Lz48llRldhYnTb2aW6b5nsFToWG2YzQyeYj8xP64\\\\\\\\\\\\\\\/neYTFFYjl4V7HLr83Vzm6MdwQjlbd8QhFYCroaq28EQsP2LpFK8krn3e2zQKU6DOzWB3A1ouyMDa1\\\\\\\\\\\\\\\/ZyZsIbZmErusRnjgNtVYuq2Lyg1qQ2XaK9YjPEUja98r2wxFJ59V3+Fn3ANtq5MOepUqqqxSIP68Yv1eFeqeQABv+VULDRP0gg+1E+8kiLwg9dL4GQdMRpfV58MxnxDxa+qIe8DaxtcG\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/EhDek0JTwWUHITM7139VsstuaFOMfWI0FujlPCJJsE9mg9tGW18sdxPhgbcShflCrluB+QSzzT3WclGVSgYvgGIXWfU0sCKWAoIA\\\\\\\\\\\\\\\/lUDRLctRZlXejvHYWAlY9Td90BiRExbd0XkYEKQgfBilVGmly1UHiExH0GSuBnLE34UtNjn\\\\\\\\\\\\\\\/5D2rQF\\\\\\\\\\\\\\\/Zblds4TcuANvDwHvTAg1r0O\\\\\\\\\\\\\\\/FYVbJ\\\\\\\\\\\\\\\/7KhRGgzN3lI\\\\\\\\\\\\\\\/bh4SxOYIfxs42EHdzAMrJrXJYLb\\\\\\\\\\\\\\\/uldAv4b7HkpKNDVPWFNlCQhgyZp6INGbbI42gVGDT0BXLIIfKNfloIEuIsi2AgLJFCRN5KVLs8sGf2Vj7n3Fi5KEwi81y4JboPePTZfD63O\\\\\\\\\\\\\\\/6bzQU5gzm+44VPXybZ9cOVHCnHO+hed3YiB9ZGbOZ4yWdOv2YRKqpRykmr8Jy70Hm2P9vtvFhiurbvjbTpp1XxIQ5xtxnJo8+DWE9BNL52KzkaEQ67KF7ISfTVsZoZUb8KX18HbWJ8mtxvSRc3yDf6uAWSPHl3ir92aybm6Kqy3xsOmsXzQcdNT8PMHQsjw6UtxLSRNurn\\\\\\\\\\\\\\\/fXy9MRtS4\\\\\\\\\\\\\\\/tmUAOvhqXkkOJbgtU9YY0viQhwkWx\\\\\\\\\\\\\\\/FPFyWbKP30cmnlYCVW1QA78kSsOBpWkM0e0UnA8JQfOTXEFCgyuzyXpnhc4A0wlhbvHMLgJEwAwfbOXfMEPqq4CLMp7HN+OEt+h2IpVkC8EWFC8MYOCBZEqoegwrhfsXuXGUe+Dew3iSJ5ukp1z\\\\\\\\\\\\\\\/3JylX4U3\\\\\\\\\\\\\\\/do5B0x2srWJSC0epL4G6HjzeRIDMAa15wair1PNAdKfu0uvx1407w8u9h+QP\\\\\\\\\\\\\\\/yPnBVqVBxSbAK2bxhWJTEfSLjxycjJCQt8\\\\\\\\\\\\\\\/l1uCbgeaKxFA307bFCSlWO7voxQRW\\\\\\\\\\\\\\\/UpO8mOpgI5TahkHCzwiJG1pN05ascgFC+mLnRITqzaaveqavZYduTJ\\\\\\\\\\\\\\\/oY+VIDYtEDTCQXjCoPR2Gp5rN2UoTenTxCMHQyQQcI869\\\\\\\\\\\\\\\/XaMaUf5zZ4m60\\\\\\\\\\\\\\\/zaOpAw8ocpW6VNHMzZE6uJMmm+G9Ooy5dpkQ6fHdErHEvG8a0j0iBfxmxOUMNwMGxGMHU239kfq2ZNTefKUOztTkcTOYsfWUMpr7W\\\\\\\\\\\\\\\/kK8tTuuyKbYPAxoeqYO8LxrfJeApiTACO\\\\\\\\\\\\\\\/hFxwZ7k5MX\\\\\\\\\\\\\\\/Qszn69OAFsprgJuAXwqRxj57vDnr834KEqvBagxAL1JrPflpuTRUyxc+RuNCvNm6spZ1WwMg4R+50ZgJpd1ROT2doPcD3o=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022sVfjbPgy+7ZDA9A0VgTFHw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002265c6fc4adbcd70cbd67006c8133d2a65b04485b9b3d4b80cae43c909f8c7bf3b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A235.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A235.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0207\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0207\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0207\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}