{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022sXsARkgutZ56HCumJ9AmohuVbHxswwSToYNQxVpRiymENxar4ncquSOCiELpd6OkjuJHWLDwfU0BW1TDvyc+EBb6ajhykDlsIZDFeOTZYwC\\\\\\\\\\\\\\\/PvKA5i1E\\\\\\\\\\\\\\\/RJVp4BIaV4WjGyduqxMzMwoyswpSLbFbfrwEzcYYkOpvuuDg6zI4C6h5QOSKh42FdIciKBQqWFG1xK00uqe2QrYeztW0gfdzI5VT2nljiCxv98JhlrcjrWfjbGScp+bYx61wYFsavTLZCtVXBJMguQKaiZ9DSP3qzICsFjLeE\\\\\\\\\\\\\\\/x3TyoQfrAyv8zWhgCN3Ytt8K8T6zxYr1kT2utcEzCIdR5mLu5Zv+jhWqVDEp60AVwxrh+XvLnqevZGckuQ15SWnDKpUV40wqSLtEmCLbzvLAib+os8lNLJQqEvUrvYHpj2H5K8S5ApPh8HQ6mQ3veDGC64o5ENjTQsgQeYjMGyWVYzeqyVkuZAGsiWKQ5ZS5bryFGkS1G+sdppexqojOax4d1jt2nYloO6dwP4r5vKLMaMNE2JnIvLposGYATfRcIFMQe\\\\\\\\\\\\\\\/flvA\\\\\\\\\\\\\\\/R1ilbzzZnFHixwKYAS0RO8TSyYAb3vgLXFDw2wnqwQU4Mn5UfuVch\\\\\\\\\\\\\\\/cnyVrl9hMmdBS0ja+kEckq\\\\\\\\\\\\\\\/aQBs7SyXvK1NPZKtUZuQ2bgCl6zQOzSWx5DNKGtQn0wXqK5QUzj3JwDXT18tPMoU8YhuGrUJcB+sNo6FiVpX1TPnzaulw0rhy8SahXKxGQjhxUFmmXJoeu8Rp6UXYLn6mIi\\\\\\\\\\\\\\\/XK236eE+L2fz0TKW\\\\\\\\\\\\\\\/Lv35t2SyHtqnyA0rDzRp1QudioBpw5bdl8wrUUt8G1RV9Ww0WgEWS87JHr0jcnhS7ToV19nFdMSzJEUzka96tiFfpvSP7LxCwrhqVNp4GObrJmclftC7hhlqodSbQefmsRxazyG3G3qEKTdE6c\\\\\\\\\\\\\\\/9kRJSL1G1mjQzm0VTJ6cKzZd0s2\\\\\\\\\\\\\\\/KgRBrNh6Wf3tHHFyRfWHYFQyfvXH52gSXJ+wBNFKgovRYz+mqutzWf9eRCmpyp6Qi+EKRsOFr\\\\\\\\\\\\\\\/0xZ2cnj+9iP7g6LEWkUBliY3dmqHql3pn\\\\\\\\\\\\\\\/dF6X9Gawol0cSsuWtKXAnWCHrD7eDGL\\\\\\\\\\\\\\\/iASHyw9UQsJbuzwX4f0A1EXlHOmqNQUZQUu4EPCukHvsbeZStba20kxo4hvRtpJFtrHKZIFbXKB\\\\\\\\\\\\\\\/6UqG9kiyMCqF7x0JgwX34ZXfKtJquHFW8sMwgTxnT4fGCB34JJqjt4KRtGj7OMe\\\\\\\\\\\\\\\/NDM0Y4hXSvTOy03U3b45WOVLddiGo0WJWZnb6cHa4O8fbZNBXJqVcAHpjvdOUYyJhlVizlUkfDnOaHmWlvi\\\\\\\\\\\\\\\/b2jVtfQem0WkmG\\\\\\\\\\\\\\\/3FParpU\\\\\\\\\\\\\\\/Y8yD5QWbsqQsOmWtVdJc7RDj9MEHU\\\\\\\\\\\\\\\/PKnRI747QBNoJU+4Ih\\\\\\\\\\\\\\\/AfnF4tkeAbh7IMBRfTeD4ZyMW6m6HEoumiVkbbf9MTjNIKsE3sJGEWQThEmiGvyCaybtiyO90cokQsAzSZ31d6maCeryMhRLpdZnS2Tp6KGRCPksG4UkxyHKckIbq1I6EvTQzu3oy57tfdSVXS6r6xSdo1Kr5AQOrTkR\\\\\\\\\\\\\\\/HJ9Z\\\\\\\\\\\\\\\/Lbxlo1KVD2HXvDr61AP2uW7wl++6oEJm3ESlxEZhl8blTtTg9NiTNKlv3zkJDAg\\\\\\\\\\\\\\\/zGxWOMDbC8qj+pcX8ic0ERZuOFsiwnNePoUgu3tw\\\\\\\\\\\\\\\/BGtL92Bh26bsOiwQz0XyaqYXKb8QoINPmFh3HpuBzKk\\\\\\\\\\\\\\\/UdnZg3Is8q6WEPgkiefLxgJYz4VD9vAals\\\\\\\\\\\\\\\/wYEKlRSEyAxwuAk9dhkn7g2kgtu6T4\\\\\\\\\\\\\\\/HbS9btLlq1r0wu8RHmb4Vv2L3OkncsbJ7wMSF781W26V7Nt\\\\\\\\\\\\\\\/7xEJ9XDbNZ4RJgJSToy56Z201uiXnvtuMut5x\\\\\\\\\\\\\\\/c2V10PvCYg0Up7bD3dsbzzPanFmdNqVpz\\\\\\\\\\\\\\\/z1RgX9PjXzU5G6unLoyDAJWK7xYHT6KW\\\\\\\\\\\\\\\/yvp8pIalcZ1zzf3ZwBGz0hndhSYjmUMB6pIGc\\\\\\\\\\\\\\\/cR\\\\\\\\\\\\\\\/r0+TGkLOxO\\\\\\\\\\\\\\\/ALJFdB6QkAfTgO9Me5AtHz0FWuLccP7PQtBlgrUHUFky7U9rixP1KsIWGgpGcCYzh1W4jNwAmprI9bZMRnO27kOWjPdlyzCBBidbPN4uJoQaiQsblwjRNTFBrfgQB\\\\\\\\\\\\\\\/tlO+TOdh4bTGAPU78G2obUqJn+PX0qJ0DwsHGh7wDFGZVf63WMZ9xxAPVZSYFgedmXk5\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/zy2dvn4iS4bQcI9nvobqTO89D1jwXqA0nsOB68SFoNn7wemXBxxKk+5p1NxJSFFzkWaImPjUHix\\\\\\\\\\\\\\\/fm1usc6HzXUY4sGrfRlLwm+Tfw5Y+OfDG0bpFyOFAVuF4fn3JM3aOmUiV5ygoNShpoHuGY+Kgr3ODVbgqqZYNv7p81yEKjjHpjMVy7CmndxElD8mi0yrbYT\\\\\\\\\\\\\\\/dp8YyPwjsQjmfwxHQXCSoL4FTO0I7x0A7qaMdfmnTbiWA+isEceUl2vYhLeDcivJyBHqXV9RQBGHxmA5ypM+rm0XbWTnSi8GBM4\\\\\\\\\\\\\\\/7foP3hJBYg7nE2gJmSBD6miwh3DrTOZMfc0F\\\\\\\\\\\\\\\/fPu81fxPXYtOPJ5UOpKlrHOBBUdjh5IE3c9AVkhy6jm+HGwIIf4ufFzREHwAi9i\\\\\\\\\\\\\\\/9Ewpgx2Rna7cl8DsTeCtnjV1ObAS4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022TH2gwREtgPbQpbOWDyteog==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b84db55006186d52edae3955212eeb2f040b515a32c3537879c6eb6d207b8556\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1451.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1451.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1306\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1306\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1306\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}