{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022vQ9xQPCGN7IXU1MV0OdOYQAZdlhbCwd0yAmg8fXIw4ENoVddhXQKT+r\\\\\\\\\\\\\\\/ZjUoZS5gkCJNJrlczfrwTFd4mjYWhB+6pCVdLdLGWblX2goWRnt9e+P1OslIqe0sOiFpIUzbzgUxgXa6ChLnNBMX9TaUmN5kb\\\\\\\\\\\\\\\/HS1vwSss+lVob+5R7twmUlu7XaPbhe\\\\\\\\\\\\\\\/sOk8WBzW3ltOocb2YGgetp4tBvJNAziKh\\\\\\\\\\\\\\\/VWVTX+i4x042likaxUPt2+3c8\\\\\\\\\\\\\\\/iPfWWgn2eIncoRy8DuPHJZcelIbqMVt2s+SBzA6kvM8GToSvctJCdajlIYEsFRGdrZHzKyXxGZD3UAuvJMm5s2kgm48a3a7DBHoD55MJJK6pIlYlsix8d3U3iCWNrs5gFkaEbf6qvlkVzbgIZSoWt5uDmXNcSvvUTBjoXVquxWUrbPoJfDmx9kw0rR8wV\\\\\\\\\\\\\\\/tCQnrL+65UbJxo0nqRHi5+XmxYhC1GW5VFum8N5n1Dvm\\\\\\\\\\\\\\\/4UrfqBFZRgaxEhDsXbvWAE3jTQl5ZLluhcfhKZTiDWmNE\\\\\\\\\\\\\\\/0fer3WHE1e5\\\\\\\\\\\\\\\/hf5uOAs+LASbpqunpw6OlSGcegq5e2+eOST9CW345TUchBzY3ynFJaa+73jdhwRULeGWClHLwDtDlIFJm6LXf\\\\\\\\\\\\\\\/0C41ALWx4bBFQ3I5dbBCNsgPeIp\\\\\\\\\\\\\\\/sJFGPQGkZ3GZBkSRZPwkJh2aT4XxYkDx6Bec1pTjVnsMmrJS95cruYO1wBmXo2SCBbxLtqXY0yjhopLbSNMeeBBEoTcpf4pOIlMzh2mWSK+wZKZduLr+ar2g\\\\\\\\\\\\\\\/4qy9myx5IYYDaj3BmsTtBIWo70ja+7gf4AXYeAdx91ZxMGvuUhnMwZKoWmlwSXonRNJlYFEEZcly1Ys\\\\\\\\\\\\\\\/+WRfqFUthzujsNRSnK2oGkkmNYMCxKaDbFqglmmMTRmNCKds3xrMj48e60DpzxSn47mkFsXvx1ktdv49eFHRttTFcKM+lgrEq0XY\\\\\\\\\\\\\\\/n0plOe6ghinlQ0gWjxErOUb3DK0wzfDd1i8WwFS1c2o3gPi18P1aUbWRb2mZaC1BKKnJGQs5Q+XJhiQmxxAVLtPB6bpTzPLSbEl4izp0eBNG6nyMJddZuIregONRxHAZsHs+j43Tkw0Ae8Gv4LBKcBupvyFhJ13QC3qY2sFn+CuT2mR57FLOEJXVxF+Bu0W48EDEPesvugQWQMyhSNMV5pMD\\\\\\\\\\\\\\\/1UrjK\\\\\\\\\\\\\\\/TmwDpkn2mvlhnVcar1xTZmfSMQ9rRg8XpeJYmp5qsnOUtZaZW4MZOKrZkc1Eq5EZTQVS2\\\\\\\\\\\\\\\/DDP0icI\\\\\\\\\\\\\\\/+a0Sorkk5hvBK7rXJVEmgk9qMlM37rcO2FlU5jHCOsHY3FDY\\\\\\\\\\\\\\\/lvhG4wZQoyamx4S50N\\\\\\\\\\\\\\\/OEIK5wLb\\\\\\\\\\\\\\\/uIymtPpTC8S4FQjXcRqfdSksjIDyqPs3vMuuUNJbKGp1sxkYRZPCWHgmYXL8bFB0uvrJBHkyUSoZY09RcwIahQNT4txTIyAbXh5GMISnYwOoekOvzYbulnl4epUQPIoYgKe6l\\\\\\\\\\\\\\\/Ci0dckUmPgs8TBl9abL7dCuTpKfQU2S4iAWICGNXc9+bwQ8Rzer2YTcKqwoKwqjR2L2dEBj15Smh8rIHER7fRZBdWWXvWSdXFVzHwmcM7PWb0wpKpn+hA5ej85vgZzD9\\\\\\\\\\\\\\\/CUTWDsOxd6o4FdIZ+adciIuexeQzACTOQhqEeUXxSDx\\\\\\\\\\\\\\\/bixR+MfuAYlrUuVQaQEv2PVcgCDvlG287uj9VRRzGgocf2AAqa4M3Gb3WPFMfWOzfysKuP8nIeKWi9CAyU9ocYTFnI6Sos+csB2vPmJl7aZ2WbelYGAtI2CCxpv5s74k8dvPDWWhhWX7lful\\\\\\\\\\\\\\\/bHwz7NcL2vwtsrjKzs08SS3QDm1kIS8HrwQpieNCiKdzz0n6Owe6FXjEje7HHk+qeAnmcppQOfa\\\\\\\\\\\\\\\/miAFCX\\\\\\\\\\\\\\\/Ut+F+D8RUfThbqdVb\\\\\\\\\\\\\\\/aGCrNKLBN1BReodq+JfCiMtc2CU\\\\\\\\\\\\\\\/9pAbl4QKdOXds3+D2b3N1Tc7zn6segylWAbyCOXk8oPQQrV8RJzQNhl4rgnj8BZDD2VkdUv1kS4AT1LhnIA7MeIkMGCd2VVef5IwVux0DOtpLikpEGYgYLBi+GtIcMTgsCpCODK8RKYsJ6+HqVcfrnISrDZz1FIQkizTx669rWaeqK9M2+vl871hvwgphm2nsfE\\\\\\\\\\\\\\\/PaxsLoqO7VUNTyopTTlZ1XyG0zIS4l8ncKg1IsBtwL\\\\\\\\\\\\\\\/6Yj6jpTgNdJaP69W+lsFURKMZZglf9wSGzOvHO967k01gtkTzgE76r7GPj6iUdWQ5l6V7AbszEjA5vRGQwGwHADo5Kbe0m15WMRFb2wOHEw8OImfEOUNSj\\\\\\\\\\\\\\\/jVzAxYvL0lBUS0MDdYDjisX3F5Q6TD+oICQivUuHmqxiNlHN+SQZw6ao7nE+8dCwRuXyD3v3RB73ETQOZuJnzs9ch6DgwI6YnZXVgKZhrdruSDKGqNG993UC7MkIln+SgrW6Y69xreyB6AIVb0sV4VZlEWHdJg1gRz9yXPzh50TVAt233TlW3lGoTyp03Y5tOLojeV3ea0Lw9+yBcTg2c23rJo8U\\\\\\\\\\\\\\\/s\\\\\\\\\\\\\\\/3qUpDRXKMximFUg4NNECr34m2+mPjmBVvNDBoVCg6pFYWyZcd3iRmSsGZx+AUZDfMnOKMfBv8hkaoS8sCRAjQr\\\\\\\\\\\\\\\/drjrB134x2up96OHzf7mwI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022mJRcxLbaZsLei9qsatUEbg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002278a657d9e7a7d8f35be9c5e2cb31dbb6f39324036740de7a6b2cf21c7f2fe48d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1482.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1482.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1331\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1331\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1331\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}