{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022iEhM0q7ZEi39sLEKOxqxccSZjS180gk6Vs\\\\\\\\\\\\\\\/5yFvzA2a89O\\\\\\\\\\\\\\\/M3\\\\\\\\\\\\\\\/5VAdj0roYTQthFq22tYHVP9ENlVlmUEdxEeb4LLq4RjPvUXArbGQ4cIyLvDHC6n\\\\\\\\\\\\\\\/BjXdf7pw9pxbPIcOGwcw3IxM3Qct0+mbeZD4aDyJebYlbfV3+Tn0n424EQk2TarTIs13stRevwBowprEWba5UIWnostCiWYr9AzC5tjTLwU5qTFA5PEpk\\\\\\\\\\\\\\\/82z4L7EgiD3yL\\\\\\\\\\\\\\\/2VKMeAhXeJjDiPB2IY9gbjkIs0z1btIE9NeyKrHgNEbk+cfdFfT3uztet9iy51kjNItA7y7e5nTxsOS6gaDoE2jkJwEd\\\\\\\\\\\\\\\/lDoRA0uoa7Oq6JVQ\\\\\\\\\\\\\\\/2XqN\\\\\\\\\\\\\\\/9PwtYyg1PL3RPgkxOVwNoAJYv2Fns5ajH3YbckwzLDtJp2N345aAXKlJIbd\\\\\\\\\\\\\\\/y9L8z03jRmIxNzKaQzruHj4FDXRV+o5E\\\\\\\\\\\\\\\/Y3H5ff193bj+m7\\\\\\\\\\\\\\\/oRHdvVwE8YzlWpqtD0TkwLY4WQ3Gb\\\\\\\\\\\\\\\/ypEBrvIDmlPf+uPbubZJKvM94bs\\\\\\\\\\\\\\\/6LOtWjdr3XtA0uPJK09CYmvk4IU4WTWmk1e1+5Tsp3mMqp3xcTYx0m\\\\\\\\\\\\\\\/iaWtIvnisCSxY\\\\\\\\\\\\\\\/Yd2EWbWfb0olVWgL6csKl\\\\\\\\\\\\\\\/roEIp\\\\\\\\\\\\\\\/FrNy2TBt+S8VRm9i74r2r4NGUM4fC+TQS8DcouNI62\\\\\\\\\\\\\\\/oEww2MuOFVtRq9m4Uif5spgE5b\\\\\\\\\\\\\\\/fFVjGP0nirEcLJrbWZhvavV+tCT44OCc6+kTIiinxFFSC+eno\\\\\\\\\\\\\\\/RgO2Q5HyWpxEeXnKzBPcd5Juep+CtfRMPCvjNG2DM06sB6EuRxr1NHeQTxfM0RHfxnsLNaq+3sVhnPC91q\\\\\\\\\\\\\\\/gA8XvWDXCLn2gfM4h8pTTzW2eA5G0kmGNN6vKkq\\\\\\\\\\\\\\\/HKOnZwZ2XP518Wrk1FMtJnsOq\\\\\\\\\\\\\\\/wxn6StG1fIrC8OLCcX3d69tHdZjGy\\\\\\\\\\\\\\\/mgPB2pk8eo6PTpQi2AD4J0g5dwF+dxLT0dSxAFK4FIvYHM7TH2U5y6bcoDZ6KJiwr6iDDUPx+I\\\\\\\\\\\\\\\/9b1ZhH5\\\\\\\\\\\\\\\/MAYWmXMmasUBQs1N18FE6nsEuLLlWisA1uYhNQKjDkQwZ9Q7DWBYg73+6yRsQtBj0TcnsIixEa4BqLAxYCcmknqyyLsi22nd7ROOhg4smxZcm5c9JNs1vZ9pM4Vi6CYNsW0Va8CLcPMnKCMcG5p8uRuYINjidghpY8IXu+tU5vJa3Z5L7rou9u1oaiUEHgd1kcNFnqthuhSDn7R0ibMcNGRbOAQ2V6VPNp1ZrcQ5uDX9mEopmeXCdqVJhIB8ze4zpZwvZYyJXvjBYQbachDEIUopMJTkSc3t4RdRA9F1slVskzk\\\\\\\\\\\\\\\/fgIlZ\\\\\\\\\\\\\\\/KIU9y335RGHDwf79Zzw8kUXs7H3PIdITYJxxj+lKCdueGpqMtNLR9s5rJfv56da\\\\\\\\\\\\\\\/IzKmWZCSQJtwljiKEIEplwePhwd2\\\\\\\\\\\\\\\/s06Xt1VO1Ljip6atOrUwWOF+rzTOwoyXcfmjfFRPnLnSRs5ycPefAFc8X5cE+oktez0AGdpM5GQ7sido4uv5MesbjV2GqtAAQgpPrWzO7Bt5G\\\\\\\\\\\\\\\/xImGpjmNGoN1LsiALpYsOwmO9rWWUTZJe2U68T7M8vKdy1KAdUafhfMqYg9dp0v9faXueMg0YylYx8O1TweP7OAcAsq0ejJTR9TXkD4TAXNcmngBupPG+HMGxxsKlolqRv89RaPKGuR\\\\\\\\\\\\\\\/kon75ZoqEhFdiMEEx9LM\\\\\\\\\\\\\\\/0vpSUXFvzomNXFYkIfes+VBt0P4QHzs7FqxiaEsYCTarhvMtqzWr3v4Z4DLl3Cw3584HmIdxEGhKwzDbco594GJ5DhChZjzMW7yA1T1lMD0ktSYujJfDEEdN1vQYptnLnt5l5yXjTyBZnsP4VknaBLYtLAhmlW8wXQU5PJBD8RLmZH4iIJK8aBLxYrW4Lrd1MdpSKVXisLNxjkNmNbcqaUgAGyb6CLmPLhnsrcP22VHr7O8hbnELlA+x7jZiae5p6b9iJZxkaYRgSOsC37xIgEuh3JmeOFxEvjq7c2x1ZOgy2Lav\\\\\\\\\\\\\\\/rJ0ZqGI7oSbLWwMBo1u\\\\\\\\\\\\\\\/xU4k91XqFVU4wvOFK+J6q7RU36NpwQKdFT+FVUCxJXSWUeWxwSiY6rt+7BJBmZgL+4dBctwjGDloO9DpEZ3bUPajRsuvmSInMFnv6ykEDqDi9PIeEt4v82+LRV1PhBRl5d4ylP5dShnOHIcR7QAjJvmcu6cm39Y6mhY3AWre2133r9G5eEK0pVXfhfwytfO2A3Q22MEM59v07I\\\\\\\\\\\\\\\/AZ8wpc\\\\\\\\\\\\\\\/zXLGsXBuxVenN0KkfbvrkUVRlz\\\\\\\\\\\\\\\/wkBttx722ENiAxoA7UwbZbopzObrGuRY5jgQXND6Z4TLjbG24Eb45fXVyOc8dthrVcDjEHBsP8KtI7m3929NhMWb0NUKiTImKUksJHU67J1vRmEEpsozO\\\\\\\\\\\\\\\/ZKWx+o2rDGZHRbH+gbuS4KGX5aRorLogV9nQOEQsUvCNnNopsc86yKmK5kxbpc7feJtRXJyLD7Gf2iJOogZbKRzHuPGtTjVm85aJvIj9dVLjIUpwc\\\\\\\\\\\\\\\/aJraxax5TVCI0Bbo+Qc+6PjFwXoz4yUjnDkPa59Q7Hmo\\\\\\\\\\\\\\\/gJ1uRd6vn0KvVceBtrkdYlQYiEmYT9\\\\\\\\\\\\\\\/QX5YKBnvnS0JT9qGUqPvv99odSFw3jfnt149\\\\\\\\\\\\\\\/Qrspo4ilieww=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022kYRun4uEDdivYtraPw+Ydg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223ccd37c33562dd6fa0b9b4a71fa7f7fbe1e11f8d7205aa2d99864aae688b0877\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1086.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1086.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0979\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0979\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0979\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}