{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022USd60giKLT2XOwreMnncI5yeCD1P085gOFhFFur9qyxmkBxedymJm98hHIAhTpn\\\\\\\\\\\\\\\/zwpEv06MME0A\\\\\\\\\\\\\\\/t6u9gQi5Aip7uYV1kcZct2ijjVX0l+4DT39TZedF\\\\\\\\\\\\\\\/ZzJnLJsDUzAKk\\\\\\\\\\\\\\\/1qvnw+lm7GTF74i+dqzG+pRUGyiAGw1PD5JWUHhxAfwaAVlIyMFjH93ki0YIr4zLphEHjxi+eJ67ROIevZojGhKyHLAc496jOUe\\\\\\\\\\\\\\\/g+AaA\\\\\\\\\\\\\\\/ur1YxEMAlmWjY8oc1OOJpMefuSqHsrq6r+5YuvpuuWYIWVbQiavIjSFr3O1XhoQe33xT9C5oCwnV4ehpgxcLNJFv3SHe42iuLglsxgLhcLU5a4H4cnOzQbrIhsOZBSIon\\\\\\\\\\\\\\\/xEwJhcwoGpU9UIU9hxXrF6sLq2qO4mFt87BsQDgi17fx+iBKy7tlwu1ArOHMqPir+fFmqrCxwHJ0k4rU83wc+jsSznZj6miQ1x9LJd2dNDenA6ZvnJCzZ0tiF4tDQMIgLEEt8QE\\\\\\\\\\\\\\\/O\\\\\\\\\\\\\\\/qjj2SIEQOmPfkQEwYEaTDErG51ceAFCy\\\\\\\\\\\\\\\/+68VSOQ1Ex0smtklWAfNWiuGXcTsgTdwOxU2QBsVfT0aMe8NfDPgXTrHVjGHaNaJ5PqU2hLeAxNppruciRMSC2O1lPouuLXedFxB3TPJ8XwzK2lm1BsRqGt+KEplJbOFX8e7KoN5MrJ+CTuRuei0QEyPsi39+FIKVXiPEQ8L4AaSUaL5+VwkwI6Ubo\\\\\\\\\\\\\\\/KMIm5JHxtZADBbyLvBcIuqd\\\\\\\\\\\\\\\/eTjAH\\\\\\\\\\\\\\\/j5AQZk8dR5dWWJQeFlLnVGF\\\\\\\\\\\\\\\/QQ9lrOIaDiWGbXZrXYKkjKtm8KYqxUZZYRJjNesnPhbdwcOWcEGukfjGaiH9xRnm5g\\\\\\\\\\\\\\\/Llz5Blh+UPyJEAO9nmPSGLIAOf+2qSA8LWGXQ8wueze8MQVDgjDZPQiHg3KBQjE\\\\\\\\\\\\\\\/fm5B7umpv3MkJdlFeSRC\\\\\\\\\\\\\\\/D48az7S1gX9sjIfYHRZL8FxtNKMEaOWFAwd7RYqML44J537S0edFHr\\\\\\\\\\\\\\\/UPMgvkWb4+ABG3yh9J7U0YJxW\\\\\\\\\\\\\\\/iw08MS0uAl5jaJUHLJnOapWkKUxRpBQD3Aov\\\\\\\\\\\\\\\/eS9e\\\\\\\\\\\\\\\/XmeqpaPRPVzpteBYCanA6J1toj54RJLJ9O\\\\\\\\\\\\\\\/Bwr4wl8xKp\\\\\\\\\\\\\\\/0OcZuvj3bnUyhbg2ewJoC3lp1Qc8UDY246DbxDwZtJG9zcibKhTGj\\\\\\\\\\\\\\\/hqUP3oO4TnBFOMJaNTmuZOW41HgCTprTbNdeVQw+W9\\\\\\\\\\\\\\\/zQYaiBSERGn4KUDOIgBgv59hbIOyQG8uzGJxmwqpaCQQJhTmF\\\\\\\\\\\\\\\/EmlRidLezOoQB7v2biLaHjim2zvtGQanAcXg00p\\\\\\\\\\\\\\\/0RfH+YsCbBXG+dwXHxTNxPLDKhQWrOJA0sbdwz7YISY+eNJkChoHof9SN5E6D9nHfonb7a8w7znh\\\\\\\\\\\\\\\/CFY2Z4IUmNHP3DsvnGbBiewo3L2Xniq+Ucyk8AaDQ+RXlMFnfPtAmqEVFFDNOr\\\\\\\\\\\\\\\/mwRDOFsgnC9FcUfjan7DJhioXqGnwa+An7dG\\\\\\\\\\\\\\\/a9uiOrSoxotuz9o45hFJwE1v+mgga5jzezgdxe7VdLIB9pjNr05qAn4\\\\\\\\\\\\\\\/YcyiMhmZErSYaezpgmvP4ezPrmy9OG9YqY+EHrqHKzXgB9yKoBI6luEqKrwaBP92BPrgcHL0c53HGlSsVBs8pTyQ5KIukaxNeQLn\\\\\\\\\\\\\\\/BF0OJHYx9473AK72aFwF0tUVrMB17Tkxel6FqgOLCf4RXfBoqSwV5kkwxwBK5nHRRrwegj\\\\\\\\\\\\\\\/FYVjI\\\\\\\\\\\\\\\/J6ZCKzbik31LOafiOXL29WE956yLhqE8ujlbwN7noqYv8olZLCwTDWAKh7vd3a4l5Tyc3rK646kkRlOqogh0ZvWSjSSUlQkX0v6nGHmWGmTwXFnSQi+hfG0lm\\\\\\\\\\\\\\\/5AWoXZf48oSkQl6iBP2jH4Dg5kTPkoadA9YU\\\\\\\\\\\\\\\/eLyS6QDzYZoAUnUmJa6LE9Jw0aqFC36S\\\\\\\\\\\\\\\/wHIbNewktNwALaMi39ztZ4AtiXYgnwPD7iWwDLBuyQoiZlqHwmMm8alp3hkRLMqQaKb6O49x1qqHYoDGo4SfAFTeADrwsibSc8+Z\\\\\\\\\\\\\\\/okCuN7x+Ez1oHP+8N4\\\\\\\\\\\\\\\/WSji9\\\\\\\\\\\\\\\/BMQsCh5A\\\\\\\\\\\\\\\/tPly1lE366nG2++Ljw3IHxq764JsDN37zH4U95k1BY6Lb2LFGnr3rYCcJM2bdFzbX6zazvR9ydjHHnk9hBPNMCtyT+BPnomqfXM7MxYL2KHvGHTf4ftjdvrdOA0qcpMgghzYqjGn\\\\\\\\\\\\\\\/iYYD6\\\\\\\\\\\\\\\/9KOKDXErqlEfXEX9Oz0Ko5SelxT7eR5saLeeXHVw8fF2ij5WuWz7Juuh7JB3jKNu1IL7\\\\\\\\\\\\\\\/rKtsi759Yd9mE6eMOwCHZPdc8HFqDxnMhjr7QCK2tQ2XjO84VWUIRAg1OAZoo2w9Ih1BbnDcL2OVVrOU6TmecxcdXR6X5NZglbenFddxjep3Vh1kye8R4zlFXof2T9AA79DnMYuxSYN6ecSvrPdPC4bxI9qJIV+C0WLgaMRBEaIEMR\\\\\\\\\\\\\\\/qJA9ZQcLRhYeQ3QvNlnAisbn\\\\\\\\\\\\\\\/pSJAbbxzWPHJcd\\\\\\\\\\\\\\\/+IRcITSYEtBVgMqXJnEp0f4wxa5vTki6bgUVtSnsCxc9RhFIU0pJcD4gx4638rPwVAKH2kEqQCeOSy82w3t6h7XJddXwFnkkPPhnYSzbDb7ydO\\\\\\\\\\\\\\\/phmZqqEdft4wrfM6G+tB+x19bprlxfTvi3dwXLQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022N0Nw2PLzJC8djg6VRPoitQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022dcd6fa0e1515a58401212c9558514f39c03bd46a9d0a477df6ce84027d03ce69\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A637.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A637.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0558\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0558\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0558\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}