{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Y9Z\\\\\\\\\\\\\\\/K+PuF8aSOqlsY2RKIf3QYFzklyk74Ss42IQo4ljoeIyCa0scrCfu8+8stR1HSZKYPBYZifqITXGXymTZfHTZ\\\\\\\\\\\\\\\/yLLQDdk0EzvzMdgLPPt8zpKp8YnADqDsSvrmAthtzjQ9MMN8K3ebmXBIfTchhUJY1pQBvweqnoEUAOvSrACIuFIj2cW3UevUaoe97QCQjhO1extwxLtwVJxgdK1ikSKpi3rsLzPBTWSYFLF50Kfk3AlgGubXdik9YNrwGqWMSTRsXtbtS94Khk8y8aRj5c\\\\\\\\\\\\\\\/dspv8h\\\\\\\\\\\\\\\/fjSbucF1LTYmdkai3Q0DFrlNLGzfC9JhWiuCJEC\\\\\\\\\\\\\\\/Ph+yjaf\\\\\\\\\\\\\\\/SL4PAQUPtDxT8DTme\\\\\\\\\\\\\\\/8LLXgpVq6fkbNPkaVZftOJVot8Ykb09\\\\\\\\\\\\\\\/yMX9dnf5kp5g8f25SFjx825y0ssvJ5\\\\\\\\\\\\\\\/cbDbb0KFtaN++IT75XQ6S23B+MI2LkRVs7Ko63K1H5C2hPNWChl5iuvNWF2iM55thOCts6q2vp1giiFfUzBe6KUO3Hv09ufFaXqo+wS2QnfL3ZdIAQaKB\\\\\\\\\\\\\\\/VNdYPd2Jc4KvAIuP1NQR7Y28NNGD0HN4YhT8sMwu54BJdlZWAd51VGD3GD1SSSQpnQ2n5BTcspA0LMMjuBXY7P1U+P7qu27REssXO75l4JVktNvFOm\\\\\\\\\\\\\\\/uAysQ1I+vWBmrFr8aKoY0mte\\\\\\\\\\\\\\\/F+sUN5+iE3yBOdYwKhFKkDzmMKZoWLPTZ3Jb2oH4bre6\\\\\\\\\\\\\\\/OeFbmBqVi5eAMgsLlZCSOl1fKE+eQDir+BqgPyp3b\\\\\\\\\\\\\\\/KhQmG\\\\\\\\\\\\\\\/sVydz67l5DDcqAxKchx+z6c5nxIHdsN9kUwEa3QoVyn27Cs2Kihxblis5dwUt\\\\\\\\\\\\\\\/9JS+5P7Ycv\\\\\\\\\\\\\\\/4Y45YOeju0Vl5hZapo8Y3pNKQPVQSsM9GgNwSJfFd\\\\\\\\\\\\\\\/jbFyBejENmR2dR57LYEAup3uCEBirAtdRNFcyYJlKPOtY+lcu8tBd7ZPVGhR0DWJO2kqpgRBPebsdeFVBvqMJbKMFHi32z89HvbY0H6S4b0zPqC7VfJDtZufTiCUXH2ojUuXTHsK8USfqbgcAgC6D\\\\\\\\\\\\\\\/aQCv5mo+2S3IvhA\\\\\\\\\\\\\\\/xjSXzIqnLUushhIlrAeEl68fNuBKxkzC5Ha0Y9TIAtgbvwR4w4OjyxTMwfrJ6REzJ272+FQX1JFqmFBy4VWvRIDmC0bdLOvcEvYOk3b0xoumyGes3PXO\\\\\\\\\\\\\\\/hON7f\\\\\\\\\\\\\\\/7FJ+W5NoujoOZPIXzS4PbsMN2JvI457iYwuGSzPFnKmFKSIcQh2J4k9XbXDjtwxVPgdupa6tyeJoGZ6w7gYsTFdsJfYlwZ41phQVGNws\\\\\\\\\\\\\\\/a5DUruGZry6NeX3wUxW4TUVgKr5Hb\\\\\\\\\\\\\\\/zMEOaeiMvYKH\\\\\\\\\\\\\\\/dK5us4E8xVGaROpPAfxfaP+5Oe0lRkKFWgUqlASP4ItcCX6KJdsNjmsA+LlKziCgQ\\\\\\\\\\\\\\\/m8jGb+yJ2nJ2hNhFqBPbKYQX\\\\\\\\\\\\\\\/sE9GWaNYCDtMPMXxytTpo21tKHDWW24gyVQm7O7AAXLPDdqwu0H8oLZQMKRGpenZ04oRUiw6+urxI\\\\\\\\\\\\\\\/bWhTrK0JBgGIZeCUjgEm+96Se8GEBdZa0tgNDko6Rh3oxalTCUeEtvOqbNnUZcFsf0TBuaaCEyLtn3ml9aKDD0d+dkxhbgBflogj7WpFU+zkTbD37cI42kIt+5FW04JXoJBbwlvlNFTIxWTkp1XsXA49ei3d19JEYq1ilhbf++lfUWjBenz9iZB3ft1jwFaeHjolcfvFjlb0SEhIOgwpcIsd2YbihoxkABz0\\\\\\\\\\\\\\\/CA9idqoIZw5KehPXeDKQRCK+BGSL6JgB18LqQiQ10f7AIlJzaqnHjf\\\\\\\\\\\\\\\/rMt8nbTpw24A7sqnez1yy2vKmJHfhtpK6KvkL\\\\\\\\\\\\\\\/mgk6JSAGGwyThKWT+RfEEqd\\\\\\\\\\\\\\\/x8XdiGvtv9yQoNvLGsYN\\\\\\\\\\\\\\\/6wVcsKAhJxuTW\\\\\\\\\\\\\\\/oTua3hgHMf3L7jzi8hWZD0qHt3s\\\\\\\\\\\\\\\/4NKzXeQ8JQcOmJGa44+adyE0uOc6cocUh\\\\\\\\\\\\\\\/YNZ0KCEZ0n1OpHw7YmmBJUbIsU7YSHdmz14xHmzGnQ+vIBy1HwQo3hayGadKd7EWHm3dXxqwS4Wc0Xi471fbfOxZFMW1red37tMO+N\\\\\\\\\\\\\\\/yd1pto+l9bxaRn4GX\\\\\\\\\\\\\\\/y9X2Ge3IXVh2pMzfKBqOWWycNOVYJw6aAAMubE3W4YTyRauNXzti8YGW6vYm3Teg1tmBPApWvcrtOJ3iqThtjl35ATyYmlzLVnP9yz4XVTQ\\\\\\\\\\\\\\\/pK25FWNRsOjKZNrWTtEMBkho1vP3j\\\\\\\\\\\\\\\/wgzpheq64LaOrsg5LzvADxNdu6U97QwaMjlHtbinPnzbGNHBzNdT6ejRNZbZKFAG9xhowrbTocHFWGEqP\\\\\\\\\\\\\\\/TG3bHSRlCYB0MpbaPUKInKKNoAA\\\\\\\\\\\\\\\/adNexH3tXS017BCeEFC34uRq8E61NJaOL\\\\\\\\\\\\\\\/tpKZcL6Wv2gQCN20SUCvPaRgYRFVYo5u2K2lwg2agq+gha0ZSDqgvc9nKdXUla67z7TrFF75SdczkPz\\\\\\\\\\\\\\\/lswo5qe2RxZPndGtCM44\\\\\\\\\\\\\\\/Q2dTvV98v7RWWB798hZtcRtgIBVvCvT3lzlekWn+aYw8Wd5yvosqB8JCo7LMEWt8DMXjtWYIXgTrskWeSohQWAY3B60QXlbXKTqw3StaBgTaPH2KHHmTm8e0+gkLqUZ\\\\\\\\\\\\\\\/w25XxYHlyMfdjchtrHCssm3P6JrXGA89ilWNVCeA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022VmpWm4z4KGBF6MeDo0lJ4Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022de730a0bdb73aebab199290dbfc531484ab0f146c900482e2586e66d55a60c36\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1673.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1673.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1508\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1508\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1508\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}