{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022awwxOOwlS+dFqcetT9D55kB9Xz+za3gDQ5xZ5HLSqQvD+NqmEn9FXNpuT0GWQwTePZptG4bjo\\\\\\\\\\\\\\\/V6jcVMhJki1OdUHJS+VfV\\\\\\\\\\\\\\\/iA8izHGKefVcCA2woRLj1s6qRr1AmqH+L7yTyk6w8CUcDhP2O\\\\\\\\\\\\\\\/brd9SElmSuP1IudcHdHczgYogVFsHTl1lpjl5MUHLRhb9BN1xu8OW\\\\\\\\\\\\\\\/0WTTJirhT0N8cjkdttLmBFwPf+d0x\\\\\\\\\\\\\\\/fm6QtgLGLo+g28beYtZ3kJPU6arZ5zBvfHWlzaUs9AuUTyRUvJQ43iqekbPB3NJjbPtwAoVNHNqstmQGQvGDUu1PUr2Lb3\\\\\\\\\\\\\\\/BWWWKkYQIjk97Ds1jyXYQ2hwqdPwIH+KntoaRPM7CAOttVUUxLArTYXvkCAeLMveZWU2yGkbCKoylsbSYGVIZCkqCdvApdUdcdSbeAVZj0XEUNTS9\\\\\\\\\\\\\\\/x5wnA55SRpWS2itQoJn2ldupo3mwnrKd\\\\\\\\\\\\\\\/wC3+Irr7K\\\\\\\\\\\\\\\/1l0IT5D\\\\\\\\\\\\\\\/K9e\\\\\\\\\\\\\\\/gcFjlLz7RtgyOvsB7lBkf4Fw6sdWSwRnlNJz7OZRIKCw0D5J5DWY3BCv3U4XlIF+h3ezZsUgc1PMDhoBH8c8pVLYdrYXX4wRteKEAFUr43k8W6XWPDQyhUEDJSRQrapDBFp9v2XGa0EHOZfQ6EpK4wwSSmX7AtDa0n+vA1KmDjkptT0ZLw5pTmCCjTOjvsVmonNSuHnewVvxLUflrs+R4C8pZLfXEwDR2qRdfCIJabmB+EyqIpDcavlgJj4fUPrWl7ue+xXD2DQz9gyixaoTc3sEUaoWacInbpc7\\\\\\\\\\\\\\\/CXbUOf9yexkrNwDYctcqYyKnpMzYQgAvs+qRcZudbtrce9uLAI0uXv7FrxC8Wff6BPLW+DgKS+BEjz3BRzcA8f7f5BZKPBsNTNhABxJxkfIx4NwghIOqrXzkFx+rJLyIhW6ArmvJf47SWDfDd59SpyLf5GAZLLym5XjVIKras1FkDkQbiIc3q7eXVMQDxX6Vatb\\\\\\\\\\\\\\\/DiWcsA9qZ6QsAw3ZC6uH8MRFovKK5AW\\\\\\\\\\\\\\\/bWA7k7dRi+65rEIVJRN68PujtJVjgRPFDnO2ILO6HyXuPt9CMIBSeO0bt+pzSImC9EyP\\\\\\\\\\\\\\\/uOdJeuwlxMgQbocpMWerP\\\\\\\\\\\\\\\/CSKQpw6XmysiKWt5+F8CQ1hszggTNeeT0ed5rwEr8eHpoDimcw9AclINj9UUDzHhKiDBj5eoKHvmk5QX3HGfkjsRanUIM7w2D5ctwx3u2RQn750aQu+0iPNLFjBZ3C6X5eVTL+Wolr2nDb8M8FSoJXLaG\\\\\\\\\\\\\\\/2FMPtWhEDSVwR4i+KhqEOOWE3epDo+pjDBn4yCiEsedMybvOweTMGohbOblESIPQGcRwnRM6kYHkPABejpIWNV3wStTZeKDKGZyPrxb67+Y2kJEGK7QJZaSLrp\\\\\\\\\\\\\\\/L25pG4hSGwXMnlv671QTrvaUwuR46IopOK+dF54KSnEon2T8fFlmkQOfO5AlZYL2bme4jOWP4Qi0+nFaozLafs7pGsW3JfFs7SYeOYSRNC9heEwF4d35xOwMQ\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/AEZTEIuCjZuT855ZbWpPaADdVXD8YE9O4IWwRc62ATKctJ5ZnoicSVfmSXR7Fh8e3CIDy\\\\\\\\\\\\\\\/sQSMHLsvD2Tc1KiSIT9SuJAtVgrmBSzo3lyzxCwHt9XNSRQSqO95fmp\\\\\\\\\\\\\\\/59ZP0MBxcn13oKFuhy2UieANHNT5QWpP2J\\\\\\\\\\\\\\\/qqBEOdoN3nK8IiAz4FYug+HzmFwq+XNigIu3kpXORQ6HLx2sC\\\\\\\\\\\\\\\/gCprmpvF+dngNcbzQ6x1gZ6kgyPQSMoVybfF5CN3JiRD5kuSGk9YmrJcnwlbWufA0Ezl4iFKAwmMfJjLiYLyhuHgjKkVnyx18e0cqquCt1zwZMvNo9FbNBFUpEWU1vrq2JZFY5AP4SOAj3gIlJi2nVzNGRVUNdOHqhWPi2Vew3N\\\\\\\\\\\\\\\/vXlTLxI1nhgEXrGwLczPUr\\\\\\\\\\\\\\\/menBQxY6Ur60rCjXsbVP\\\\\\\\\\\\\\\/R\\\\\\\\\\\\\\\/x\\\\\\\\\\\\\\\/XSN5Ya7ghSnF0ApuQ7Pa+\\\\\\\\\\\\\\\/CoTeOblFPwbps7XqQQ1YfGdLxIS4Az4cVrq8fm6t7Q4eOcu8Idzeaff1EdZzq9Awi42Xa3\\\\\\\\\\\\\\\/bHALY4Qnvsel6QhHJjSgRN2MWaL47vOBLrCqrbwODqq4Xtc5P52xEdoFqitkAIptktY6r6Nf8Kj6ZTKPjS09x2X9cHOcrEYB9uPR2OoaNlGafgQNtK2JgDzWCMgyXSRVwdY9t27T7p+z6iyZfdii2uY6UBT5IwAe8r9OdDa2cw\\\\\\\\\\\\\\\/WZBo4v5x9OcwhqmHiVxMt0oY0PEyPPwvDQ0mfr7OtSfh0PHtW3Dh637O++jkIrvDgZ\\\\\\\\\\\\\\\/KFoyngnOD6fY6KqQp7l+tB1NT5lFvz6onqWvpPxD0GZs0iRlvWqpAShC3H7cCmJIuQEnfpEeLyv3pivPx3KNMS8Fi2JTbPnJ8L\\\\\\\\\\\\\\\/gna0jD8POaha5Azoprl0TuWMyNR0HrIy3QZp7wh8jwxWgMdgIzM1qe5cz9uOfVlY2zep4jF08MpYRydq3QLuamvi+0t00xZrroXjreMnNLHsrFE6QZLkZGiYLUi2VTqhRW3FJYDMUz6TZJ3bMLKp7eRmmt085j08zIQpQnXor+jjvkkzzDc5tC1sonmNN+7ZcroVyvQa6rU1f8Qw5Xn4Q3n72d0hYSMedi8P8W+dyo+w=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u002228aT0V\\\\\\\\\\\\\\\/m6yXPlDL3C1hHbQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00225e2566e93d398e69eac3af5ca080e8bcde1ae0fc300e1247666fa9cc7d92ca23\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A561.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A561.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0499\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0499\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0499\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}