{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022YWqCQR8HpfmDul73KtTXrCNMOI2ZM+K7XLAFLvU0aVFL5mHTBbZAhVkvDe6tMBtP7M05OHUY8LhtxKJFS9fTDTVOc2xiRNRNlmxRvY776p5tQI68t55ZXysW3UexSfsPvsvtwh\\\\\\\\\\\\\\\/w1oAeiIzAeBkBFIiMkmUt2bj\\\\\\\\\\\\\\\/E4tkn6mpnJvsCJUSWGCkF9vicO\\\\\\\\\\\\\\\/dFqhqszJKVxqN7hTEObR\\\\\\\\\\\\\\\/NvQJKtX1lVhQDCYadnDw25GMUCtDHFpOvLM+Yj\\\\\\\\\\\\\\\/CsKdvEfi4Ha9rfcVc2UYd6IdJWBJqs0g6v8SBgWQo64onqhgQs2L8k1auuuXzCY5rsjaVS\\\\\\\\\\\\\\\/Q2Q5aDoa1wdF6S8kWTmlsKJZF53lTDZtYQ2R9WEwKPSqdCKdcfxgzDzbI0EGHCqLzQzL8CnZZP83thiOFaW6BtjnWL7EngvqBNIVhFHzIawR0W6obt75nubJLA0rTj6NL0QeGm755KZz13aUyX165oC4Gf9SegAJm0N\\\\\\\\\\\\\\\/X9Ob7rNn29SfEk0HfJh45P4z\\\\\\\\\\\\\\\/lmvktXv7786usR+X4zWv4ODQbwKWRmIrGS2ZEgeidzK53TtBQUE\\\\\\\\\\\\\\\/RKZf0WEn8IzPb9KSq3IdHm6VjwN4EC16o4fJPXlVjV0Dfmmzg09Ejr3AkCSxQQdm\\\\\\\\\\\\\\\/6ZGWaZM7GhJ9cqoqsjV9pij1e9Lvc3EMMmY5bU7aBZR2AFL\\\\\\\\\\\\\\\/TiPIZv6wGwIdK1jloqOUILuzIa7BJAyDFSOJmBw9t\\\\\\\\\\\\\\\/6097XeMY0+Tuzh88hTufQqwhmqkhsjMOuw66Nq5p\\\\\\\\\\\\\\\/wwANHC\\\\\\\\\\\\\\\/aBJVJacaJUpGDlLaC1cY4y+UdrcFasOO3UwB0l8EPQv1nKeyklrQuPnLMSnyKg6EcyAlF7zEcYrYJHBBCVJnjhT4qJ1HwnuPJwSejYPs6AiOEteH0oe6tqyXmh7uLoFNfefhvpCOeh0kRiyCZQ4BCl\\\\\\\\\\\\\\\/vbYe01qI8Cm0C551JuUw7DMWZ+JDDKgbI3quhisyD04VCpEseVuBwHVb7cO5ygv+VZ8iE8MPp0GoeVpkSHOMZ3dF13GM5oMVRsJDlNMlvmmuFEHvA6gbIdD1BRs2Y5RKLPWy4OwH01xv57QQ4EioYuvLW2OfJORrAs15yvdJ3X878M5pL42puARDYKI6gTFBMfzIt9kdHvFoB6qgAYxEj9tpL++fSLD1NHFRQR10F5HGA6q\\\\\\\\\\\\\\\/zWG+90bHOpqvJuwFxUQKx5hodvKoSb0I8nol50o5C8P8QvrmbUDtAuPuGyvunWEHna9gGJQZAjmukIj4HvgtwPfuK5mugLHB1enQDyWgLEXC\\\\\\\\\\\\\\\/ByQvF54nHYeYXlU1a\\\\\\\\\\\\\\\/rXh8Cd9kke1mvEuhGfDNfLfp6UTJBnX6yUWQs05arm8yqtXMBB5p093d8wwh8YW5rageH8b\\\\\\\\\\\\\\\/PhkJbA5cnGFWu\\\\\\\\\\\\\\\/KPdX7PP+dAFLZY3Aeosv7kiBjxygazNyHk00jHA2u6fEA+wjHg7mNciHenyaYFifsKOdCRoBS1r72QGCH9D\\\\\\\\\\\\\\\/O0d7OAeimON+hPAONYpje8G8CqAT3sCTurwlIR4fK1JOGhc6XJJh6fni9ReuAIvsKKcbdUyLJMOA9qglEec\\\\\\\\\\\\\\\/lKQ5scBM0+0lqCQgrU\\\\\\\\\\\\\\\/uH0J07LwE2WXgipCL7iG1XXrgUnolqBiAPVcD9LKKLjWS42+Xon5ojoTaNplIPRD2uZtkBsvIzT\\\\\\\\\\\\\\\/M2JhjRCZIEhvWtm+p6N2MQFrk2mjiEtYDgnZIsX+3sNZ5YS1zunPcR00pu7gkseEH\\\\\\\\\\\\\\\/O5E9960KmlDZ1awYcaV2fbh\\\\\\\\\\\\\\\/A5oYXkFjBHh\\\\\\\\\\\\\\\/rffC5PxGeR0MJoOC1QoVGmwMZuw9e0Rah2wSsaEevLvwFcRW6M9VT1+0KuAxLsYqHeKNA5+jyRZW9UgLHmr898cvcLxQ7m24bbUzdb8SHgU+Fuc1TFHXeJVJRifkAiSbtmlT2SYdEoP44QgOO8VD8ZY0xsP+fZmlXlqXM9ggeEbpuoHCwoyYtK43g1SOkKkcnQOfd8CQn3qiV\\\\\\\\\\\\\\\/+Tn\\\\\\\\\\\\\\\/3qy9z+UjvA45hMIulnoYstOIFoJWH4lsAmodJoSyeJCclXseUTnV+V0F7LPuGsQ6HnnogY57Tt5GgWQQwnPSR2BGcIA15vEJgdbQ0fqQ84FkQss4hV6qxAZ1nJf\\\\\\\\\\\\\\\/6AJobiVqYQ3Fop7QUUaT3bdR6i+2Rdl5QdebW7CUVgHccJ0sRL3z8aY8yR2NLvFYAvEBAtf\\\\\\\\\\\\\\\/nYkOXA9wE7f+cQ+CPoWMqWAv5mXKQ5ep\\\\\\\\\\\\\\\/l7R64qz\\\\\\\\\\\\\\\/Ikc8Y\\\\\\\\\\\\\\\/ljvuP7LCAa5Dc4RNIfHkDIWGt0X9\\\\\\\\\\\\\\\/e6hBg8vV7Mm9C3pRoaVmu\\\\\\\\\\\\\\\/txn4mG2gsYDuJYqssTk1XhIAqHXHz8caJB7p89+OZ4rVo76fZcXu1S34\\\\\\\\\\\\\\\/+aQtwoX3x2fjWpfegIjyLo\\\\\\\\\\\\\\\/mWxAweRlmnSlYYODxRC9crbamC05Ld9a4Urq\\\\\\\\\\\\\\\/DLxq8QpEFcN5uoUiCKjEBCOltbeHsWME0OPjwqHdrcmUp0rs35aDQ9mXpZxelvGhsKgVcsusTxLuehx7o7LrPPbNF8Lx8cBK+4sRBfxZHI255S4aNbYKei\\\\\\\\\\\\\\\/74xsMiCCx4528HpXw12FwXkB7vbwp3AwNERwE\\\\\\\\\\\\\\\/18qA6nktkIZNRxOPN9R7Y9hc1YaSlq3ZZw\\\\\\\\\\\\\\\/8wchTmXQGYvQ4fhgl4B8XL3siDVGVbwEc8G01gh\\\\\\\\\\\\\\\/Py5ip6aAGVjr\\\\\\\\\\\\\\\/LLlFn4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022LZEYoZ\\\\\\\\\\\\\\\/PTmEUz5AvZNLjxA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002202e3c42f486735e68d75ab085ceb0a2e1b96dfadbfe811aa6b401fae362287a6\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A825.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A825.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0730\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0730\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0730\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}