{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Y0xoSQbg3kM3AmPeAU1kIauNKIJlFe3\\\\\\\\\\\\\\\/wW49qWf+or7HqjsR\\\\\\\\\\\\\\\/HiCfYUrzC\\\\\\\\\\\\\\\/8cEjJOm6EqBKWWaHJzshrs8zkQDQXR6oVOtwlskWFms2d9v0Dx2Qpi5uXjZbfgs1BHEQ2swe5GXrisVjar5Hm5ve40j76wxOBs\\\\\\\\\\\\\\\/b\\\\\\\\\\\\\\\/gsBC7+nkRg1md3devpe8p5LwzgXVXXAW2H3uqKCYxjQMaIR9mz1h9hn27kUNDn6SsJqsFrfyfR9YJORKsw3TDEROJ7Jocnib6RJq3d\\\\\\\\\\\\\\\/3gcHXZYD\\\\\\\\\\\\\\\/jp2D6rgwebdGA33nhjfRWrPKJXMLvXQNqpmGZsqnGJUj6CqT9vgVh3C8H74v9Y7vcaIjvoLnEejPf6osQRA1EpZiiiCuVB6frGLpjWeOiFu7NExwh4HszY22ffaBUUFZFymc7ygZXpcRJOc574MfwNuWKot6AGCQUGBCbIZSv+Fy+Avu\\\\\\\\\\\\\\\/+JLWPwYVJVijft7K14cAyUWOwOyHWkzE8GZS47tzP8MYCRCS\\\\\\\\\\\\\\\/i8mzDtQz70ZzMUA1LyORlIsI4Xp4kwbxRkHIQzEbwHLto9IdB+ANQjT35xDzrumq0ocyyxjC271AO4w7NSXecA5MbxfnKLAB6UrrBQlJ02QVxaqzLXG8u\\\\\\\\\\\\\\\/Q1sxL\\\\\\\\\\\\\\\/OUPBwzfhAs4408vmLpsSGSx+o+krU9XxOKZuemDAolVBDz8h07liz2gFBVSfHzS1r33QyHEEG41gmB80i\\\\\\\\\\\\\\\/5NLKN2JU2\\\\\\\\\\\\\\\/OfhGMEXozlFX4Fx\\\\\\\\\\\\\\\/Darjj7HjSOgy3touhh0uMeISjbUsELZKDKR+YeNVHRzMiND6XUmn5BxbXD9NrIAHrYKaAuaNetd87F4e8+awJjPUFn1m1q2wd+ku+ynLpuuWiKP9rKR1R3EqhO14LKVGXtZRUEdSSEOpwp9R9eudqyX4HvKAwAqAAJyjvutvXee+FaHyNXExq9aKLakfmBk5HPKGGLbmX0da0bkdFZtJyK7hUyUHD+652\\\\\\\\\\\\\\\/bVC3Ej5S7c\\\\\\\\\\\\\\\/b1hUCcYB66zRFNUAcWJ5rE7OFidYrkR\\\\\\\\\\\\\\\/Nvq0rrSx\\\\\\\\\\\\\\\/082pOEyBcpvZoyUOjngOSs8kht4oFeudJucej9alqCBWXls+XzeJeN0cZ5qovuAE4DsQrD0HQPvmlSWtLiCUZxj\\\\\\\\\\\\\\\/BOB\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/1kOOoTRqh3z3Wbb4fCMLBoDJoo8kJNZ0diJPIsgEczKaap7RbKOKSg\\\\\\\\\\\\\\\/amqPjG41JEWh4pQtXrjDZXFGqHzZWr3OS1rk3C4WBeXqnvlh12bAsl0xqhnjFS5NzeqRQE6Ld7AJX4DA8E+NReoIh9wTEjCxvHY\\\\\\\\\\\\\\\/sibZ+cR4HsQhca3++VWYPSX0l0vvUDdvAyC5xpPu1erhhk6UpfpIr6Wg5sljmtICzJWxrKkdvvG7qtPtb4mkUSBGbXr65G6D1a1oz0ZSvRRtgMizy+oKECAtbuqU7mCeBPohrK+9yfbArECZY9yDYIo5mLgzCBuSJwH4rHYmPxEnmNpkPYSbDDqd4f2N2IkTQGPXZg+SQGlsMoL3R\\\\\\\\\\\\\\\/z4U3KiwWMopLnNgoNQwFQJfET0aV0bh8oxbkG6XXHaRFZ1Rg05cTrDLUqkmOqUz3cwUqift4BqgCwpz5cOkH0qeW+ewIKLf7zteTDjxSA+f\\\\\\\\\\\\\\\/Q8Pve\\\\\\\\\\\\\\\/RtNHMtLWUf3G7gTuh8kx5FxpAetdrRaovaJc9mloNS4mXJoo8J\\\\\\\\\\\\\\\/fM0ps4KMpuVgwX8H23oyywueMzPaXKN4YkqwmhBQIuC87wsfiZf5SX6xVlHBUnd26PH4jiCHP2M\\\\\\\\\\\\\\\/B2z+fW8DFxAGgmUQtodu3C27yKFLUsvOx0MonSaUVWgBR3w1Xs+YvMhq20E4lbVJul08Go8wp4KPRV1BcqAETT11ECJDcq6WSdjSdj6K1Y2sPdzgbZhAO1n3TQ4hnOQk4UuKfL6r7WTjqDfwW6pCmwVJJECGHu8x3+Jt7PcgQyHtnvrma2U8KnJku+W3LXnH686NRPVa0sOx4x9ARcHVmrA0qyhq7Hq6ZtpCh+B2ewAWzRkk1h7nhZS88Afw0cmJR5MQGelbhNxFNfvvYFPgiHRF97hnSFb1XhXdtfN09q1wRybToQUDiXssVhUiqgdS1wrTKcYnKQ1twr7oZeOmT1846QuiyBMTKmboY93KlsbOUL39uia3muv3eDpFamMERSjWCoyKoNtvM+Iw6M4uwamO+sTmQkYHrz4kK1A0VsAynCNfqTZtR4zS4ao1SKuQ+3o2bnpbdad20pO6tqf5g\\\\\\\\\\\\\\\/vzVWPRBqgbHp6\\\\\\\\\\\\\\\/KWWSmai61NRHuSHBA2wdFvy9LbAuW+bv6pjE0IDj8XA\\\\\\\\\\\\\\\/lvJIc7a8ZGOJ+G42DOkmPO5IkQd7F\\\\\\\\\\\\\\\/p2+fw4tKvAU22GtUFG6MuiMgW82bGQbt5NNHtnd3HrdiIVwIgm6saJSpWhOA7G58NGeoPmp7gCT7EHRSFJlHZ3TpdXZwTVwPrsXqh8NVGtYf6Lgfi+t7wELbYXeVsBBI\\\\\\\\\\\\\\\/5D9YY2IPSPBT2uy2TRfFyuk6UlQfhskb2zl52jt\\\\\\\\\\\\\\\/tfpd2ffuIJ466Mx+dTLWOUFZ+hFseqp9Dg6kDGlJA8FI4SDEf08DCUDqt8g4k9LOVMNoh8a+xMjRmac0Oi2MOu5OmNEhAEQ9N2oyiJ\\\\\\\\\\\\\\\/bZB0W3EXjDdZH87lhkAVjvVJ\\\\\\\\\\\\\\\/+z00PD+219yJxu7L\\\\\\\\\\\\\\\/nRALZIKvpRC+W3DUv61eRjWg=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022JB6uhL8jaiz+QaKJOqRaZQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223af283dca08db4b93677226626bdfd396b2d68ba316a791fe70da3f4cb829179\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A95.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A95.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0085\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0085\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0085\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}