{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gWZFNF9Ywtsc21sIyODXLxK4FBLqMVnM+jUNWElDgRb8G3trtLXbg5JBpX7mW0O2WP5bR5KgifBDSDpD+o\\\\\\\\\\\\\\\/+KTndEL\\\\\\\\\\\\\\\/eDRrfs3SZeKT\\\\\\\\\\\\\\\/eSv5gTL0nZoVU\\\\\\\\\\\\\\\/mcp7WpxLhSV59XazitRSK89W1V9YwudokUtdU63irwa2LSBJ6C7HobjFROExHUY3N7KdpL1SyWRzj7ULxrFQEtR+tBtlfOt0AMeVN\\\\\\\\\\\\\\\/evTg9JxqBVyZgVBhKTiFWd\\\\\\\\\\\\\\\/DcgYCe6R\\\\\\\\\\\\\\\/QvFBVF\\\\\\\\\\\\\\\/yDDPcdq7NHWWKc4eF0tvwyppI8uyNF5vk8A2fSFEz\\\\\\\\\\\\\\\/dNJHVe6Zwd6ZM4ROrr7xPlCwfqhGLKpH\\\\\\\\\\\\\\\/nA3DmZRZPkebaSyV7W7c1oPM43bEniNJ\\\\\\\\\\\\\\\/LtlSRXoXYUuQ+OijjiuCn1onJ0Yvli9ah+OCpm8bicFxpaztqCfLos79hT8vFZFsJexfHjeArQQWOurfMV25xb8\\\\\\\\\\\\\\\/RQNp4XSJ7HNx3VJpKc8tekqsQBc7actJWAEQAPlZym7Bl5aUawlj7y8NxmQmlWQ\\\\\\\\\\\\\\\/utXZ49OMPtqi7KeqnAe3cvl8eCkwSfZVQBLInsTnlwDp+83SK\\\\\\\\\\\\\\\/bvj86daEcuO+l0dVmfoQRcvroNj628M8EmPnFF4JEmcLxwPuoBZScWYs25y1w3GVwx1oTx\\\\\\\\\\\\\\\/bbnQKWurNYZouT4KDOPfAOPgrpnVveDnOGkljuve0BAqDg3xRo0j7Rsu9gl4jTXHRjZTK6YkQHUBAm83C1I5yEFh89jzQ1sjM9iufj6xn4pobrtj+Mg9oCsYzxo5jP64ROl+8Z2izqVKZ1kUxNxYlXcZtA+gKA81n2zLBM\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/eMXy0EJ4jOVJPiMK17wp4MUQx9pBIwX22+WuM+4yMtwhCsdQcHAGRFpsuU++ELQZz3enLaNl9M86d6JvbM1NuxKLfnVokuUxNZISMdCd6nXvSKEd+eE5oS\\\\\\\\\\\\\\\/PAx3BEuL+DvA4sLNl\\\\\\\\\\\\\\\/A09Yp5IF63CNtK8wmqvkM2uVswh6H8kirHknPCt5M5eg2w59VBA77yi\\\\\\\\\\\\\\\/HwiWB58lkAsqIrWqvngO0jFoyR3zuEa6\\\\\\\\\\\\\\\/3vg44jQ+2Ekx5\\\\\\\\\\\\\\\/vaq3qppKxXh1iXKcilfmgkp4sc2\\\\\\\\\\\\\\\/06sc7HrlSBQH9B3FzyGDblZ+O9yLLgMHYzyuAM3Siv9jub\\\\\\\\\\\\\\\/vTPiwNVqHvslJN1e4Hr4TITyimGMGwWqd2i9qtTyf2NcSOZetLvB+j3zSUZI9dQ8UedGI2b3p1fQEm8s9Ql6P6W10w4tAm7\\\\\\\\\\\\\\\/yEAL1DJL+37VexRVZPq9TxXsC0mnBlO0OYGq4+FjBXpkDf9gCAN7K3h2WcSMC9z5uMNhqZ\\\\\\\\\\\\\\\/wmOwNcI3RhXsohPWDOHlDpV7DPf9NeCgta2JcQNw+B1UmVfA5QyCQ5HUcSXgZMbOSLnkVD0CWc2API5fcY5G+QU37zBY69QnuGJBEVd9LiFzboA0BnhfPVzXYve8lxTHxvvIS4SDDzqC6l5\\\\\\\\\\\\\\\/eZeTKQz4YTuRDEa7UBL3WAyj9V\\\\\\\\\\\\\\\/bTQBqTDoMrlaBqW\\\\\\\\\\\\\\\/7l+Ee0PKPwOgtubEnK222b572gbOS+LlPdUKtxhK3PmdmVkxsr8ufjzwInx0WJOajfng3fkU0JuCQUKxxbAq5eES5ibE4vFeIUoNWhbQ2PtpqR6mnoMSkFKeEgbADJa8YrEZ9RLSDRh\\\\\\\\\\\\\\\/ifj3UywQF0\\\\\\\\\\\\\\\/t+VNH\\\\\\\\\\\\\\\/BoEkHWxlkCrSi6Jehc2NHPg\\\\\\\\\\\\\\\/g4tslGv3IEzyVqVB\\\\\\\\\\\\\\\/2wj9vyqi6dGPsFsmF3Auad6WYbO0c3rvOoW+qyPkSAmLJsbyKzrk+80Oi6mzoxPxHCfetChCNBf0oqX612h9TR5iXBA6W3R43I5mTiYwR9oVtM1H4B2wqMxpJ4ieBCtD+hoTdl9gMT+tFIjq7wNpPMzPShfD55Omqq1dQ9iaWfaim9+D+igyYM3SHEbBF\\\\\\\\\\\\\\\/bDqLEnr9+j52xBIuunEtM0iPEhQMglcnMHY\\\\\\\\\\\\\\\/6LMBCPr+ckTZ810WIWAfOTBv\\\\\\\\\\\\\\\/UrsemkrGrCfZegCMzki7XehC2f5dH5a6KOEI3B7MWVRpwHGGTMvDo+7EjTDR\\\\\\\\\\\\\\\/W\\\\\\\\\\\\\\\/p0gp6b2ub7BLu5ESv+xG3lMtZ4Bs5t4OqI7vMctUv9ilud9sUcZe9Nhfl82qzNUvI4uzhmlvaWIOE35+26B0bLNVk6CQMqYzwZZaf6rvi69nSaU\\\\\\\\\\\\\\\/eCeWnqhbJmsnHEl21BPUfxuqcRz9Ls8+Ukc5wBg1oHeedVWkMaTBaUOBGFPDpxYjxA1f71iz8Eh1WiRU2lPOmK4dDIn7VW95k9CjwhoMHrt47XXXQ9fwEjlNTlDID3wQ0aRULwIAHGqHkW\\\\\\\\\\\\\\\/piBi9WpDqMlG8iFrUlqlTNnSy+cvVOnRiGOyfizLjjQ2f2fetMKwEAGNqZj1geSUCbWaQSkOd8isJy0AYLoKg35PGCpjX8+B+elxCLXwF3qBubP7fJWT+shZqriMvUz1OmVmUsWrK8I1k5FHd\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/bliDeIhatHQTDf+b6Spo+sARRNMcZ9IYfLLUxqI9da8UfRfEXdx0SNflvXXttBqXxQ1JPUYuryrgFDHWkbKqGx9k76x1SgzhSQZqNApU7r2l8EKLk4RFKOlxKL1pf4EhBUzQMatGMWvBXR2qflb6bLXsbb457aRtqaMjGc0YNDQbRvxT7Vk4k43IIb2NeHCaQeu0wDzmK+JOWoTv5HF4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Xn2FBcd8fLo2Rx3YC9beYQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223a3dc7fdcd6c02e8b47b7c948d8d65a734b6a4a8bb4a340e3ff502846e67f2da\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A472.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A472.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0423\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0423\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0423\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}