{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022QKCA464iV5tMFH0r1x4EMqCaRAaQtuYhHxt97VqnTlXG27fCJNZQgh3i084\\\\\\\\\\\\\\\/jHzzXP7sEH+d+peEq26XWugQ+U2V2y3Zwc30ijXdezhGxCAdfC7Q9qz5DQUKBq7c7By\\\\\\\\\\\\\\\/IxyV0ZRxjv5fNbi1QP6T8VRASkcfSvZ\\\\\\\\\\\\\\\/OMl\\\\\\\\\\\\\\\/+dyLmI4KLWUVl4giTGikoiQ0TXHysW61J4CoKyZsyj5udawPGKFyvln3e17ExygLDFqo4wBOIE2QiOPY20qdRGWyebyCmkEuTnWqmJxyt4JGjYg3Z5E+SWxVJLte9SxZL7iMe7AQEo0eanZdaBjdT1oRbfaRK0T0Lyq4f8Ko6FnJc7yuFdFBUyCuxeI3azc7UhSCpewXr8zma85lxAxpMPkhEK0iTYqylW8UK1Z14aFjVn5YtzFdHHSN1fzCRSF33C0vnwkL8Ifz6nWudvKJtEcIi89cuTZ46oO2L+GFsjuURL+sPrwKq\\\\\\\\\\\\\\\/zMIdSazCAd9bBafOIw+YgwDBU0XU5k6S4s8Jz6FZ6o7gc5i6x8tXSJswROmpBl3eRB5QPb93SDmScsGUHlimsJ09p7aoo52Br3AGPf\\\\\\\\\\\\\\\/DKI393AfhIIEKn3yHFyyE1tC1Lh3bAZCz0mraeiUqpqv2cYnc5TuSl6VwNx43AZ6O+pgx5Dn9cd2S0UhKL4tCLBcBeZ2kelZ14uz\\\\\\\\\\\\\\\/3MhgX84NGUZ363oY\\\\\\\\\\\\\\\/prRnnro77MHFEkX+QoubrS0U0R0qTB07S2puMyzj387obB3mdTzkVUIvUzmTDXAEacOAhpE0gKjIDQYvBflMSgbiJgdspua0U5LjUyWfxI8ATgc+iGD3M95I6PW9LO\\\\\\\\\\\\\\\/2TwRiuQebjvzWcnWgmXR3HcoTb4rU70YodfPpiOTvih6KedJPD6CB\\\\\\\\\\\\\\\/GZZ2vljA2wpgu8a4c8kgByqAK\\\\\\\\\\\\\\\/OrQtzBRakPTDXwWR+fq6A4wvaVp6vaIkz9aJyA5rXfPRLKl3Wj6uHlJoOkBJwQeOw8gQRU9fXB0aIYUIFAktbF2w4+ABuyPLB+66fLtwOWjt2m4IjNGNR8ZDkdpXFmQvtyuogc1mvFtQHGlmZuHpjL4HbPgoKsU+mpRUj69+Ah1ba6TzgaH8\\\\\\\\\\\\\\\/WOa\\\\\\\\\\\\\\\/zaTeRcFujR\\\\\\\\\\\\\\\/xrfACfMFVUdudhtf5jI5Vrynx8gO02NZq7osGXOhIegO5Dvwrem\\\\\\\\\\\\\\\/mnd93isRa0gf814hC9qFgtkI8vHd5gx5hgAdy0kTjDxBXSwRGM7YiZ6VIqPsCQ2N4kbm7V+MRtY5PlIwf1YrWBZH6RUkvmCc45DQDz1RdTFnqN70wCnsNlN1nyLbCJnFy8VbSPRZA+xkPqA0gf0nOIU6vuAJZjRuRSQRwaFgmaJ25\\\\\\\\\\\\\\\/10mUGX0\\\\\\\\\\\\\\\/5+AAp9NKNeKihApPESlXvxmnSrCctItpnFBNcCmIX8YrNjsNVnzG5UCaClduHMF2NkEO0hkaLKOCc1FNmuieO6sWWDWmIRPEOJi0z4QTFWKGJS42KepF2Bp6AvW6h8+S2cu4GIvGOyBLgG5ttBO\\\\\\\\\\\\\\\/uypq3\\\\\\\\\\\\\\\/3nlRyreMPR83L+U\\\\\\\\\\\\\\\/bcHOwhOBe7JvRRxPexsjrR3ndqgGyEA6aHLGS+3BFgcfEbHL5XQ5EanLzVXQnwwXZypSPvCZv356ame3opP0ttTqzGu4RBPeEZqy9d4sXGdG\\\\\\\\\\\\\\\/bqQTV9GpjU3E9nvjNeRD1mHsUeMPmZHWUJUATZX+4x\\\\\\\\\\\\\\\/0ii2fI76gQ1G+6TOCV1vDKHBiUVkYcYytFYvVd8HTgSJPu2+52QDGbEw+MnnkC4JXvtKYSHVSNx1HYlxLOlkt3b1UNP0oz03P4J9jijqgZPfD1FTJXur2vycxy1PZSGsLORst+Y7yRuxkqUrKZgvXeSWB5Ujgv4IPyw63RAhD0Sq6+teEVmoJ9GaYA0pRxcvV0Huv1AC0+gg\\\\\\\\\\\\\\\/EzI\\\\\\\\\\\\\\\/PseocxTk4mgwHU9wEJOzPz542VCRwhsiCoGMeQRW6ZlGLPcbs\\\\\\\\\\\\\\\/+oPDNpdzCFtkRlbzuI+nRVZ6rLVQoh9FIEBNV5\\\\\\\\\\\\\\\/iF1aZzn2chwvLRWoPY56VqSdlrODvUCePllxu4ctrPFoLg59wVFKMPOuJEH5iGpkJf+PhkY2VzGv4JcXjog3WJuM+pjmOGH\\\\\\\\\\\\\\\/9zpExaY\\\\\\\\\\\\\\\/ZwRgwFKmq6lCRtMT3z\\\\\\\\\\\\\\\/f1yV9FMI9E83ABYXjPqc3A5Lz1dVGtSif3eyEkJAFelZ\\\\\\\\\\\\\\\/YXscPDjNuYOkTqvAoBDgS8Uc+fpRlNY7WHU2zNnuAJLxxSMl66BilXpREj0Nh3hDpTXLgRJfJYqaOG07c+gIoBrDmwY+Faw6kL5QiszXI9q+iEStI5mBhRWZBl3fS6M\\\\\\\\\\\\\\\/pYYQ3LYEsT2aemHR0oj2JGu83YDY2zJhds6i5G7385PXeOqdf1ws31YuJpbBQvlTbZI7Z95QdSMY46XSkKUGRjfG0fY6A+BNvSocPRhWWX955zvk\\\\\\\\\\\\\\\/NcXwXItyCM4a37nudaWNyBGqpNIU9ljmWf2+Rjym4IRjb+eT230dHQueeRmtw89ZYujmH2eFVJ+bPgP99k5iDZCCKkwiG5W\\\\\\\\\\\\\\\/blFUXVEEePQucSQeH6AM4YEgcg7K+6kp8n26aMU4PoJ72GfP23ayMBhr\\\\\\\\\\\\\\\/uxt7Sv8USKt0BrPcQFlE+jLkYJTg365fDt6pe8k4fja2F3xwUvVhp+Pn\\\\\\\\\\\\\\\/0LWaTt8PtU0PuQkGkeV8fKii4EsqaHIU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022yeChVHuQboAV\\\\\\\\\\\\\\\/uLk3fisqg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a016c39aad39f88eacaef84528ac7b5c4382518ca9dda99a3573f7391278fdd1\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1522.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1522.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1366\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1366\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1366\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}