{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022VRLS7YGPw6VJMIm7sgTL1x7RLIH\\\\\\\\\\\\\\\/Uw1icWL7y4ZVntXT+C6ZWPPwhQvSF1pTe7XHBz\\\\\\\\\\\\\\\/l4ZBIIyExGqBayzDE7SYsHB+bSqd0X3x\\\\\\\\\\\\\\\/2YfXggoZaCkBV\\\\\\\\\\\\\\\/XZ9ooml5rD0OOzq\\\\\\\\\\\\\\\/RC9jZVS+CfUjcINED8fT7QD8mHmfw7ZH+f9OHXJ7+toDqUnF5v9m8BnECjBgFwK6LsEbE5Gxe6wYw06XavHrmxA6ps7q1+uD7PS1fUfSRttR4Hm7aimOIaMhR92juHT6ao8dpVT1wmFrijWpzj8Kkf9kQCv9nWLa+mzMEG9ov\\\\\\\\\\\\\\\/z\\\\\\\\\\\\\\\/llzZ6r\\\\\\\\\\\\\\\/qwQl\\\\\\\\\\\\\\\/c9wVAfYove0hfGc5fPfOVg2Z4wIeWt4uTtN9PcnZ+57tEKs0o4ZlkZ\\\\\\\\\\\\\\\/sp2WbB3kdwapyyh7k8nRL9qTzA1Da4KjYzFyKB6xwFX\\\\\\\\\\\\\\\/W\\\\\\\\\\\\\\\/h4CECCfKlOrO3cmDIZWigOiIrfRE1FUxwUY5e0Ovo2n\\\\\\\\\\\\\\\/qU2gsYlmKJz2DOOeGoTMb+T7De5ZrA4pc120wpiNIBPdiHrxFWrKCFtVOdiDdVs2CM8lmEfb7pd2T7+PBNUydej5twGIOWOYqGW76pKuMbmWurjABzasQRNWodjIH5wmM22\\\\\\\\\\\\\\\/EMl4UZpJWBp+R6GpLq6HoFKaCwRhbjOOE94WMQw+uT3czKs6o8ZkL4NrvNwfW6QN5gshuVZlRn5Vy5o2I4pR4gDsjFIQadPs\\\\\\\\\\\\\\\/xRqqSaZaljqaJHsEOL8bXIqyVyPOb12TTLFy6gSXqtfTlA9BtqR9os5HOQWFyyyujuz45N1GasDonHyJffaPgEl8aPsk6M9k94BMT6aifNkjiFXLSJF5igFff8shQmgAnhf4E6gnjPZCc5wpfkeif\\\\\\\\\\\\\\\/6Bgct\\\\\\\\\\\\\\\/pGrlDjgle4hfpcwSUzNDSatOBINsj8hMbBxK688g7EsL\\\\\\\\\\\\\\\/8z8sJdSscL3h48GwEesb4KpAJn4iOMfJz2+iklrjM3jFytmz0CgPzfd7emaIJInJhLJzn2SsoRMSc4MvBfzROg\\\\\\\\\\\\\\\/bTHUxeqNrVYWr+SGgyeKScmR\\\\\\\\\\\\\\\/eYoGe4gXLfKzkiTNwAlRPOwNyXrxU9AZt4aetrnPeEya0GgAYboDxlzUZgU7WVR26aVhmFLp2yAY4zfbKjsWSesUNKEqoNkxxjNsZMzHVmF8xB\\\\\\\\\\\\\\\/HVd+2DpUuH1\\\\\\\\\\\\\\\/EMRhxNx3cr\\\\\\\\\\\\\\\/+Ux4xfDTPCvZVJ0eKcmRz9Mr74ae8vpaGvxSqfQNCYJBcbKICCdKTMYK\\\\\\\\\\\\\\\/loydpGegyvwcP2DBe50L5fS94M7PjoZ4TRzqErRosxbX2Wpg7u5X9ft9bd0lV0cQs57vj7bb1HJX8JcWtndrkv0xCIeiNA2WBM\\\\\\\\\\\\\\\/UZCyTzE1LNE\\\\\\\\\\\\\\\/febN7xjv0vR+GWax3S7tSpAyvTuP6suKbLRDX1MLA8c9BsSkwXTYAfPitOpfRMlGGvWx+uV8drQg6qN2QaQJsADfQ44KyaRlWeOvRpRHAV01xC3JYrr0uiVMc9TB9+OEfF0D2bVLVBsaUn7e7nAMPz+JP\\\\\\\\\\\\\\\/lnWGPlVsQHJds4WWNZiJJgneG\\\\\\\\\\\\\\\/RHOxVQXeonOOlUl8rizQkJTLZpPmMIsD0Vk+tjG991y\\\\\\\\\\\\\\\/Ahg7qxSGtYspGTcEjMQ4ElD0YpPbdnOlOqdusCZi8fiYxc8ZMiafumhCFRT30xaooLRW5yuEUokQ54otb+VqkeByjwDYNLZBSx8CAp5EIkjMGydpCu5YND9BkGDHLjYoJKYso1m+CEifdqZjTfXwgbRpQcXveWswIWRz1efJY2IiQn6ksb8UQBmkm8C1QCPddTI0+oS3yZGEc1pl7WYLK20oSl4GK\\\\\\\\\\\\\\\/GN+7gTsiC0v+kKCV3s19lAEEt\\\\\\\\\\\\\\\/ZSbRZTm78D1lQAv3nmignuz0DwGY3cDfZOFVYul6J0FBQQ3xOQc12M6IxLWS1VMO85e2t2LirPtjP18BI4C9AHvqxOpjfy+pYxz4k+TftMF7bJ0t3WrOHNlLumGQX70Q4tMTO8Sv8fpz0723DnZm3bggCEpOfhYk8OlZ2HmVBeMcofghXEU76QesfCyODWWnyO6gLQ7ctmDaIdyu9SwX0Zw\\\\\\\\\\\\\\\/netry0WqSKBKcWbI36V7KX9dPbe4D8HZtQu0AZ2t5niCazFCEN1QhdkzWyUoJXIJ6YRSxPnYXPXpAWBMuv+UBJDr8GRU\\\\\\\\\\\\\\\/x\\\\\\\\\\\\\\\/tR3i4TQ4vPXC5zFUoqRGf5DteykKt7jlMlUbFkh+6DXLmhP7u8WLSRlUGgo44ljLC9Ejef7pVS90XzMa3CdCgd61wHSgUQ8MyZf+vpYWrtlBCa+q+6QxFvuGJrkEVydnsqlzIonzPJlXQKthFnStPCNY+13C0t\\\\\\\\\\\\\\\/l2\\\\\\\\\\\\\\\/xWFhE6yMS3EhrUt9EmXdLkVHWqwsuz7ux0V4z0zcUtJEvCJOE3KlwOjDvchbYznkxLiacpvHeoCLy2DuQz1ND14xUX\\\\\\\\\\\\\\\/U1nBwl05Wzjd3\\\\\\\\\\\\\\\/L+EMo81wxkJtlcaVcFzbFQPwqhVFy15hB988XAOl4qNSg00sViDRxSjNUq0xXuCtP\\\\\\\\\\\\\\\/I9QAo0c7bHPOARE4wfHJmRJ+NZna7q57fPp\\\\\\\\\\\\\\\/H6NcpQ9agBL3A3phw0mzeR+tDHNbQKNjyPohqG5ePaxqTKnVDEfcUe\\\\\\\\\\\\\\\/B7VUK0hvx1GmJ16onapfw5a5t\\\\\\\\\\\\\\\/9ydrxVH7pBIjIsXfV3exerz7ee8h3SYdxGarovNfQOVEyr42\\\\\\\\\\\\\\\/2LIMPmfv5ll\\\\\\\\\\\\\\\/y1a1EI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022NM80jt0uqOw7q+j\\\\\\\\\\\\\\\/We\\\\\\\\\\\\\\\/1KQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00220ab62cbab438792c5574ff990be51ecc756ad0e1a7f00d080171b36368d5f031\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A590.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A590.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0524\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0524\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0524\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}