{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022\\\\\\\\\\\\\\\/TL6+h3QR861UW5L3HM065Q5GsKi3l0IONDQd5GXGzijvwvmk6V2WfxtAZgZuKitNZx0sIPOhfZn8gjePm97iIn+GWtgAbCIJ7RqQHMR9UFPcixAR2Oo3v6++iNfDMxNm0jztf30A7MkEuD8PCaYJ\\\\\\\\\\\\\\\/ic4K4a87jwSVPImKmOpRyAjTget17uOoJbpDZN8HFA1xMxN6vQg3vsxNN8CDmHkR\\\\\\\\\\\\\\\/UmgQMsteTOrnAvUwfGgvur5nXARytB0UIybHCh8p3XBIaYTDTQxHETUytWinzb0eaTQAjorPRW5n56Z038QdHrMuA7+2bni7FszblaamJTJYRuMEceB8r6L1qnrjHli5\\\\\\\\\\\\\\\/FqUAu5tc1qvfmUSiwas3P0BiEa2maBC0tciMkBuaVABciJdnDAs\\\\\\\\\\\\\\\/oTP88exg2p0+Z7HMZCsHQkVrGYXr7qF6mFkh4ikIqR3k77oilJlNjkHxVAUYE3KsSARzjH4OVsMvoT8ecUcaZL8QhPl4\\\\\\\\\\\\\\\/PAvsw5\\\\\\\\\\\\\\\/71yTz4a6vYPr4MYnY52NZTDr3G6amwX7lhiS6Im8QxgexNJPbOosI5qael170A6wWRutXkjNpneL4OkfD+aiU3SBnw0bop0pteUWIQRpQJj5qW7OdfCpvrSNnUI\\\\\\\\\\\\\\\/5H5mSvI+9c510aCr2uM9UCxx8RM5zRF6tImqGjgSKTYxpqsGQoGcWpwq199x13vQGRRRHvj7NGWxaGdyB9IEWcZpdNUw6BQMC1IacsRGHe2vVzUXJxTf7sx41zJOeVa0qKY\\\\\\\\\\\\\\\/zHEIz0XGWYIdpTsctqD4Sktonq4qRWZyFvzBsWVR+BUwRowPas0dLMJToVn1s32EhFHXnZeLBpsWtI7QM\\\\\\\\\\\\\\\/ThVAFgjA1JkyoWxBiJ+er3btbzQkMhd1rXr9ZWEyIZLqAuwyR6JXdm\\\\\\\\\\\\\\\/Ow5GJ51zHuYMFVoEtvZLzV83CThriXu\\\\\\\\\\\\\\\/Lpc7J\\\\\\\\\\\\\\\/k95PGbU3oTDUwcOxBX0m6uodnktVaasU0TsaPifsA8ZnEuf1y55lnUUwX9cQpymnb6NPKyOVRoCcEKn2\\\\\\\\\\\\\\\/iD7GcBEcI8ExFmE02vamHcBZDmbHDfGUz7\\\\\\\\\\\\\\\/A7f5RfPqXqiusFrEqMDOz65xMTIR8XNV02iBCPfm7FBZClS9afQx6pFTWt3+4yptqYKZIRHHKgIge3nls48x3\\\\\\\\\\\\\\\/Po599zkHWVaUOkVLnKGgK3CEtn4hBCcTcVLa66W8LG577W1eqKY0rTQ6qUIypIoQpuETv9\\\\\\\\\\\\\\\/3iApp5hsJMgpZzhrB4jxKByd9A16s0F9\\\\\\\\\\\\\\\/AEATkRANE6NYEcsU5JKdfGpN2FWGmbJtAfXM40QLY+F+HhB+ybVpEYYRj+zlVJsvQE8F5HCORGC+pyHyWeFQWLTMmXFCHMvFF7XMcJR8VOZx4o6HlHZ+JbTB0GwgtoHwoAd0PQh1FpWPELgBRhbDxP8Uo9UpyR7rjwTNHjDa7UrK+2Av6G9B8bb1VuzR5osOX0A7yMKZOgAdHwfUfu+Ln9NndLYhhuqHcBD5XPX0J\\\\\\\\\\\\\\\/9Yu0O789q5rz3nIvXgAoPIFWCzonqpiRay3ShnUfZPBlcSOSuuQ7jtoSnhinG1thh0UJADmj4aZ1LXrcyG9oh4WpZoiYzS+tumZm8eWpagIyL7KOD4RFjo6fYTsHrwaNv2CMA1C5E9o1ezUwFYCf+diatKacLiW8OW+yZaA6SMIaPSGg32F9WnA+D3\\\\\\\\\\\\\\\/iZBVE7qvILrYIWEMFugoKMLFRxxpsb6uYdzDvPpqVIWi8WDYIKZnykslm5oH6ME57eK\\\\\\\\\\\\\\\/FeV5\\\\\\\\\\\\\\\/i6iwqhOOT38Z1NA7JTeEs\\\\\\\\\\\\\\\/kxO27MMqY93Wi9+QCV+gIsO2YCreAx5j2qkyu4ipS8\\\\\\\\\\\\\\\/IEn+f\\\\\\\\\\\\\\\/MsGfdVB+pE30KMpeRfoBpaYNHHv8RK2MIf6dSiCwU9S\\\\\\\\\\\\\\\/GFLP5OILlXJeqzcoyYnJ0qb3Ih0PskJ5\\\\\\\\\\\\\\\/WwG88HymCCtNiqix05wAOD4u\\\\\\\\\\\\\\\/rueaFps\\\\\\\\\\\\\\\/6rjkiOi9W9WUAcYrVmoRbNAPnZ+a3F5JgSgs+FE9RJmwk3C8ZVpKCscHo4ztfZRhoMiRSJsZfJ8akQ2684R9XM\\\\\\\\\\\\\\\/vT1sWkGFxk7UFsFbCml4VuoWl9ok82LEOq1IE5ykHr1PGqTxQGuTnJy9lnP1OupQCL14kBdxwArsZKNojog+Qid7AdFC9rlFZNT5xwMzVFirVCM17v9f\\\\\\\\\\\\\\\/YziiPr9gqFkGziTL8g1MBulNhwcdTN9mSe9+SlITioXL5o6\\\\\\\\\\\\\\\/4ttiJUtJRt4IOIy1iaMONtHWo8a8uLbg29nYYlwHk87MuvvBeh74ByVwGIVI0owAl1\\\\\\\\\\\\\\\/3knrEP1gJEBkhBz0K8kaYgiXuC1GXNQ9V3+DwP1MOFT1Udc3Qtig2+vpy9N2sZqJfwMP6pX+s+dxjXwDr6wz\\\\\\\\\\\\\\\/JrACJCpIxctxN8PnKKbUPF9r2Fiuksoy0iUKCBxmH72U+ybd\\\\\\\\\\\\\\\/Vjz5xGEdWJMAxIdtCG7NUOAvHeVyCidDfrDqsJ57b2t6oAzfFZQB4KF3wl5FYl4LoSso8m8bF52xeggf42H+nK4\\\\\\\\\\\\\\\/hKMUJUCqHf\\\\\\\\\\\\\\\/sVJ\\\\\\\\\\\\\\\/jn1ewOu\\\\\\\\\\\\\\\/VeUuMncDE7WCtKo\\\\\\\\\\\\\\\/076SYD+fo7dsAIIsoDq5AlFUHkKG7GOY8O4TEWUa5jHvCJceVULPmCUmjnGbuJuTrzUlkIafRQg\\\\\\\\\\\\\\\/P+wkGv0wBSTiraVun36xekICf89G\\\\\\\\\\\\\\\/A1vV0Hz710=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022061iBWZOBYgUYEpAg1ep0A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002269d223ba382b9bfa3b1042d401c71dc9ca7910f378221dcb2a62ef88cfc06748\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1300.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1300.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1180\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1180\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1180\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}