{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022KHaaZ+pwLuHSZOybK1zwQRdygzOgo1hduQJhHJ2FjJdxWc5N3KWJiz2JVgDtsfWm1U0yNS3oAc+xL9nzet\\\\\\\\\\\\\\\/mZHA562InLuGno8REBk5EDf5qrgWAxmeirABI+vcVi1j+PA7a478Fy8pA6lkQNXc8635e6ScrdX9zAYI+CvqO2bp3ZHA9LQqQHh3giL2TN00vysGoklJEN81Ai2+bkaWy2CMkXYE+tab3+DCdkNc9bZIbAzMRBfDq9\\\\\\\\\\\\\\\/VgM0A7zVp4WtuynIllZadStgVnrvSvpOjgq\\\\\\\\\\\\\\\/OCRX6JywiIx10Hpi0n4LpLLqTrRdP8znR2ohyCl3VL1XQCtprxdRCdtDxo6pgX+vF+\\\\\\\\\\\\\\\/3r2E1Qz4U4lcFykovMDlX84oNfTMcOOwjmoj5HN2K3dmII0MdSgqt9iiCdWEOaPOwlFDEYzEYNqyUFgtZStJFy6xHeVxpHGZdJwT6YTHLokIw7ck+aPNW9xeEGNTE9CPTS7H8c3gQo6W2TSb1WjUA7cs4DIm5sLp6zj6KAgUI0QG6qtD228h5iAqfCNaH2i1rWcDOgzwNkR1huNuY62oaiLQe0ELZzYpbfF+dC6BBDxIdvUDqrzknMiOaw\\\\\\\\\\\\\\\/fF+AYLVmnbHfM4OowqUgT96egPv\\\\\\\\\\\\\\\/Q30pHWsnjKEJ4aNfbRjml8yF0uiIrfi1E21LRsPbGhGWo3o4xBp8EHa3jRih5ziHUceIZqi74JvvscT7sOnU1HFsgXHMHb\\\\\\\\\\\\\\\/j7PFnzADXhWTnQ+witYDebeQfKL\\\\\\\\\\\\\\\/qFOh7H7fijYvdKJFo2DaXTmROjoK761nKPnls4JUg\\\\\\\\\\\\\\\/u15bzzwBNvWNRBBhzBuTWStBHcCrFQ9Kjik2ymaTTnKX1aIsIPCmWsuANoHkJbBEK+ALpoQKfO4c\\\\\\\\\\\\\\\/qwy6niGcGskt0tEscu9WmUzuc2BCg\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/5Xb4g7Tl7JC\\\\\\\\\\\\\\\/PDDFv0iw153mkNfjbB2LgaZFi6rvd8h+6JwrtpMRCbH30AQDnpNoKTPtBO43\\\\\\\\\\\\\\\/MT9qQD8uwFNQlDrkXqoo0cMXww59cOJEMIdvWXEfsFBN4PyDC7Yb5Lcp2PgkJ6wXcGGWbwL5wyPcpbsPxBW4CEUVx21bP8O3xsJ05TlBoDriWwq7s+x+hvrZedXBg5Qg+3Ze+G0ai9SS2caAi3DbXOjG3aFoLIMMCmXy\\\\\\\\\\\\\\\/chEKk1VRXOSWOGfFm9ocn2lP7usbLYrl5RWgjXr76LK4hBTTeFnQ\\\\\\\\\\\\\\\/ZiGnuVDLdrxF+LY2OgXKOfCyXXGVQk6ZriEY1cacjkSHA5wB1uzlkOGhzWNhH9TIeavkGZPJru0qndaHhUJRl+IwYFNCZC56ph9l8D8oXEuBHaV2pYpuSEUnOWavEKnJCkgcwWw2aEer2qALbCi3tI+\\\\\\\\\\\\\\\/sm9xvS\\\\\\\\\\\\\\\/WBuNcMbs03z3EgJdGxQpz7lxTuDvAIYdn\\\\\\\\\\\\\\\/h209w9rsV2gFNRVkjWRxt0CQ8qYcZ4dXRqLXUXkumbEb7OUN8aBZYs6\\\\\\\\\\\\\\\/JbHEfjXLOgmo1O1YfPOg85NR1E1IoZtAbgLaDU3OsYV6yTpcoh6NRzJ6d4vBFb34gOuNbxcS4KkqSOt+dU0fMUCBt0AJ+\\\\\\\\\\\\\\\/xq6oQ+YOmHX\\\\\\\\\\\\\\\/AaELEijSVhqBvSLU80tdevgNbreXfhbycpmdadg\\\\\\\\\\\\\\\/hPGAFpD8ptjwCqyxOHHBOuJlLkND1Ipv2PPevPrR3+8y\\\\\\\\\\\\\\\/Kid\\\\\\\\\\\\\\\/ax03CQ8PLCQSSOXtHeqe2Lo37re84eNJ4wfhVQdRur90MT3LW8pDlUIlGJDjmXsNlzBuDpIOv4WvkHh6tqc7PEpoyIhMKBHFI9VH4zCZe5CQ35tskglpTr7dnevrdERQYAn12qw3HiiGLITkyPpLOeZnGVqEks68zg1Qrv\\\\\\\\\\\\\\\/42Qn7I0h08GYmLtNz5O2ADslGLTt5OSHW6BIDQRCGz2br9MGc5YfGU0ClJnfhu9kTX8SmWf8j4g4JD1DmR4S9Zuk6FlZM\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/gj8cDlLKm1zkqLF5WE601N0j5uVMXHpjQtV5sf0jDhIe8xqrwG\\\\\\\\\\\\\\\/+BjXhrgfsLQWfECEe85dNMs40GSFbgtuOLHljjFPD58lJtNdk\\\\\\\\\\\\\\\/S5q1k1w4rZqyJLIjUKBmYbWGqlZ92leDeBR8+g3ih\\\\\\\\\\\\\\\/K1wFlVNj+i50LpIL35yPiXBmwq0uvfQWEnqNHJPwjIKlpq1pjUOn1uVr6LAFfTbu\\\\\\\\\\\\\\\/oRm95XcsLhLUKKWZLSiMaMSOK3Qfeh04e8QOgdlLCJzQJKUICoPeG9+BL9ICnHnyZjmkdit\\\\\\\\\\\\\\\/TnVPBz8ZQSg3lH0ny+UYfeYWmmPpKapi1qbTKXKgDINAXcOFq+X3ZP8hW79QMqUVOf1XGGUGOhKt5b3h6F5lTgkaIirUkVUWiRhWIE3hPMCj6PoD2tuZB4SAtlQL1GUWcpIRFNADSKP6839i5VGEIrDja61+0rdEQ7pCreIgtoVswi58oV7lc6sg884t\\\\\\\\\\\\\\\/A9KV\\\\\\\\\\\\\\\/xM\\\\\\\\\\\\\\\/cKV1r3w28D3IKzH\\\\\\\\\\\\\\\/WInfe3JRCcAjCtpwxzTFRbS7wH+r\\\\\\\\\\\\\\\/fHggm922Y\\\\\\\\\\\\\\\/eyBM+9zIz4\\\\\\\\\\\\\\\/tw3Aw0tdtPEllQZJkKHi5YmxNu\\\\\\\\\\\\\\\/AsZhIwlP2sPR5\\\\\\\\\\\\\\\/qJN7wfXVMr8g+Cbx1V8ZsLKOzBZokSbuoJ8ZeElcPDhGe3yTRSKTUJUrYwgZStWaqWRm2DBu1mzqfW6gbR1Ffha0BybPXo4CX40MXNiCvtz0t3AG1vJQlBrCk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022c0eFUH97R3bzqCF4pE78YQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226fab89af799765ba1f363ce6b6a185a1d3c91461b03b31478de50e522616d2df\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1321.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1321.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1198\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1198\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1198\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}