{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022sJr66I+GpKWv37pI7FbYJMxBLEf8moP+8DVHo1z3MSL6TcG0VEQIiilGpfeb5dSDw4m1UAY5wO79iibcdB9VGDQOf9SyNTPUEc1utTpAsOUPggOC3eIwkIBEbtzHA1zOfQ2MSZdkRJd3FjRHI2wIvrKGRYgJbr2aPafOqg3GkBlR52wUKUPu7BFoWBjlp+hNtbELfOsBE4uCBgQPb7CefICfcKoAAznttyaEnR+2VAA4boMQF56VRtUf6V711TbvG8fxGPjP1I6+oWzIS8m0iu6Sl6EO\\\\\\\\\\\\\\\/RuOWZd0sMNyimelH0v5hxFnT9yA4rkCupC\\\\\\\\\\\\\\\/+F9h5JRroGLfAwuTLB\\\\\\\\\\\\\\\/2cQXKmQLgbDO2cRUrtCOGot9jJVOKtJt460kO29RxpPtkYgxLay+t9wKSTQCMhV0fgZ7t\\\\\\\\\\\\\\\/rnqTugp3C\\\\\\\\\\\\\\\/3rbd4DF+cRks1ihPmNVkRsCjtWwQeIHw9R93zEzwhZOWK0ULlYkRakiNZnYtsZVPzOCFv5vEdZDkQW+Irnx03CZOXuW02rGyDK6p1\\\\\\\\\\\\\\\/l3LV9stkFpbFOxQAV14kfEtc3NfepKL2mGyzB5RIBavFIpDdEnNFfSDehBi7Wf5r75bSDXJSQZNFdUhpWEOxXQrJK+nG\\\\\\\\\\\\\\\/Ko8Ko\\\\\\\\\\\\\\\/k6My7bzb40TxIJOszX0l87nbxoljJ+zhYInwmAEh8BIiyg9Q8wRZYpFmgqGGQcqvYGtryXr0EiBIwdIECBlyAbIdQvnG7LGbSAw1A3A0c877\\\\\\\\\\\\\\\/TR6JRsgAFG+kHRBe7nlefClVMXOr+1gV8jX\\\\\\\\\\\\\\\/4wOlAtSa67iHcIR4WIzvTfdAvK2aTgCk169KNQ9dEzvHuysIlr9BLyzLaTkzrUNWxHeCA1W1sR4v8NECLXkSnaxqlXwG7UWuVvCji40Sktw5TCSRch5MSJJjR2A29IYI7eCrVtSaU9OArUu7y5xR3ZZq2Dxh1bzGrZWTbJT9tnuvF2kf\\\\\\\\\\\\\\\/NlO7NSIAgx6X2yYs+BBULEJn7baOxFXbnFc6HN0mnUh4gIKA\\\\\\\\\\\\\\\/2HCPJlMC5pvUsPqxIMmIf+jWLU0XbbfGL5BFpjB9siazX8pKHtAxNPj\\\\\\\\\\\\\\\/VRdBEHwKIMhlasbYqFncQK9d2VKJ46KllzvjMOrXCCLJr9Gp\\\\\\\\\\\\\\\/WRSvANSXVATuLfTG\\\\\\\\\\\\\\\/poHHKqZ\\\\\\\\\\\\\\\/fTh4\\\\\\\\\\\\\\\/vx\\\\\\\\\\\\\\\/6GCWsHJCBSiAheCMVfBZZlErh1bYAo19Y86RnEC81FIl6Y2Cl2YQpENqC0zBy7EX\\\\\\\\\\\\\\\/tlgukDW+lhnQMtntZ9xKeCwNJTaYkC2vs4TnkBi8gncXS1XlXT3z2vp5Lc7S3zpuXY5MPPcyHGjkdYQ78VE6OAtJ+bzoJytQjOYIvVBb9C88mfEB6Jxo4ofSUPrSEeflWPJT7CpvjNxu8wXz9VjNVgwy2qFYnEK4W1myJ5zaJroGlgvV82F2mqGtuGKzyB3Go667PGDTDVfHlSVXk2uC6XRqo8Ig8rWOFQm9e0s9Ih\\\\\\\\\\\\\\\/FVEo\\\\\\\\\\\\\\\/73id86MwNds9epc8xyj8Y3raDSAVmxcJCIo7IX1dzFQ1dxNyjJwUOayEDu04acJaJuny1v5pEAAxwZ3SMV+D+3xp+SBAH6JRZkTfgeLyCW7Y7j692c79CSODuY7ipAnGBVBawG9CXgdWmC1Qf\\\\\\\\\\\\\\\/onTtI4ONFehJ\\\\\\\\\\\\\\\/EG2Ru6a\\\\\\\\\\\\\\\/Nct9vjBAovmV6QOzlnw\\\\\\\\\\\\\\\/28V+ZOa3M1ljj7QKareoJWPfwgV5Qdk\\\\\\\\\\\\\\\/0S0kTUbzxwyroFKX1t\\\\\\\\\\\\\\\/Yz3gihSbGmTvRDQMHN0n\\\\\\\\\\\\\\\/Cl4VYZ0cVawKdUJ6xU8NliEaYjWz5ojQ0SPg8TtSawLOyNEb1pZHu8pkSnN4gghhjvJ7Owbb90YuJNqO+PTArBBp2r0veVN7TzuWjVTF+PbUOBtEF\\\\\\\\\\\\\\\/8kudJM+iF9l6+F9nvqUHqcu7PWfnL\\\\\\\\\\\\\\\/iVdknhbe3xKEx9SjUTlywfOrBGZlVu7CHGkKmexxHiknRMv2Iz8v0wDY9AAQOvAmGDQAcufKqIfh0RIoui576cE40qh2G6FskC\\\\\\\\\\\\\\\/3tO00jNyXE0CucCclAEEFJJzoqgGKtUh5u0gDLMxJwm1DD3MiY9rGjVdiDXjuoucXT29RWC2dHpeLEpjH1yysq9cJJvtTvIg8BZoF16xtIVfvFQtuUhKditkkwFBZs3F9uhgAA4JceAuruHGozy2THnlBrkcgEtBNjthLw9Dc\\\\\\\\\\\\\\\/sQDljg9pf9D40149s6WjHn8SPjMb0wG+rT3ls3D6eQ90KAgkz0Bst2o8F88nRIX68rjxZ48z9bgmTiV5vpVGJjw79XA8kCWgZxpnX5Tp1x0g\\\\\\\\\\\\\\\/N3Wc1N4YYiIcNaaYZa5uM4B2swPXXF6Bgk3fUbRICEMf+H27lsDwSwKSzwvy\\\\\\\\\\\\\\\/szmTE5emL0Tr3VieDcjjcqpLmvpJDlFc90swUESy3okPtKA7l2EXmVJw8Kh+H\\\\\\\\\\\\\\\/7fmhoxpi6sRR79o+QrumRs+KdAcSgms2vxeUCPxqpv5YHnn21o9Wx1z93M5DGV9CQBhR3Lau9Yof8P+wnpXsO3DyFiRQq2MDw1Uotos4R2wuhqo2WzIhKJWY0q6+vb46c\\\\\\\\\\\\\\\/Hl6sVw29NTd94sN2LFkzx99RyFeqg4b+klKT0cQ2L\\\\\\\\\\\\\\\/EKbhR8jWDc6+xeVOOfDwaUPQ8oa9RCQMhZoCQH0XTr\\\\\\\\\\\\\\\/1t0Jk+WQfo5xM\\\\\\\\\\\\\\\/B6sesTdnBu+LzH2MaYr2I1vS+F\\\\\\\\\\\\\\\/QbM5im2B8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022CM\\\\\\\\\\\\\\\/PRjYaSpwfiS8shvRm9A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d5b0d690efae94c05909fe9cb817409cf4cf2b41c7013e73c6ed73b86d414c34\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1193.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1193.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1084\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1084\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1084\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}