{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022whwYRcmT+pyl54a1urMwIi6bt+i30f4ArcbUSiBdo8Swh\\\\\\\\\\\\\\\/ns7cUo\\\\\\\\\\\\\\\/IhJ8f+gM74Mh6TKogkZN96wWkN5Hxks1yf8kaQAVxVCg5vIflbhHigG+dwPHPGN1lU0YU4SoQR\\\\\\\\\\\\\\\/gtpEB\\\\\\\\\\\\\\\/BglGIO3PyNYlyhht1xOlBRvyGdxpWjZVxXZZ0mHoy8A2Z5dhsSghcVBZPwBA5HzBCGcTtaCj4OsmMUMOPNXAC5oyXlss31EwepqDYZmCApnyQD8kswRNsixy6kdCkcYT9BKirOF5jQ9dA7egxx4GgoMnfrflK5V0DdLCNXYqbEOByhO\\\\\\\\\\\\\\\/7wuFOSGG027HfisY7EqSgvQr0+wxogtEq1A5xYVIdvfQ+iyiQ9731MmP+9+4tfa818PHOKiltCVM73muAsw1Z418wkoHN\\\\\\\\\\\\\\\/5TZ0mrZGxdOt0Y4SZG4loAfXI1KD6at08jLoj7h+h3L31DzAIPoIqUW6NBzKyOsXPtP7jfS1zoxhrusqGG6jhcbDAqR5deFZI6fUHug1x2GMdj+jrWfxdLw85NEQ\\\\\\\\\\\\\\\/D7SuydWFKWPQFfLEn72UJLbe+7rH00ree2Fda1facTZqdgZDyWMr4za2ac6y7tBIchsp1csrtV\\\\\\\\\\\\\\\/oWjVI5h7iPeEauzcg\\\\\\\\\\\\\\\/vZDn7VWItkgplaochGzzmCn6QB6\\\\\\\\\\\\\\\/pPL8YFsjTnm3OtImfVXLS3ITNAZ7zkGyPxN7rYUM9D8s1Ta\\\\\\\\\\\\\\\/exMtQQ0G+nhxqEORfShT+IGpdCJoxjb+25GIwr72zmuq3ezqofW0u8wyUSSH3WyhTrsYDlX6IF8nN3F13005iFjaTrZ1GPdf2rFLLd7bR3uly2yxgKFZr1rTXg6FrFVK43Sc98Yjnxw7a8rYK8fG1J4TjRbYjVi0sBBCzrIq3M7\\\\\\\\\\\\\\\/gSXqmejWXFBJI7+alUj7k4mmQEffDSpjxpgP9\\\\\\\\\\\\\\\/8pC+06kU2n7\\\\\\\\\\\\\\\/HGExufZwC+nuLsLlqRloS83375\\\\\\\\\\\\\\\/413VhHkbizgzu\\\\\\\\\\\\\\\/QbtA6OrS5MCti9XVt\\\\\\\\\\\\\\\/haSxhOUd+kssvHDkGIxkVNEpml9A3y9zKMye555ALKND1SAIjyTENfFkB7dKrxhvBvkhBrS6UVva0wrnvTOq+I2ltoEMOuyi5FMoDTdqnX+veUbdtEtozIyoZCgE8zLlGMhVQ3DPEghuCf+TuWerGvzYADeoaiDZ+NTNPzofIpJWW0cTWkZ4Cpj8I\\\\\\\\\\\\\\\/VM0W9w7SUzQ06v92usZQgKFcijpuN5\\\\\\\\\\\\\\\/YIq9njQRU8PbrkbfVVBmumbLUlcrcaIbeMqSH8Z0Ji5Jp2vYNjDyZAZwc\\\\\\\\\\\\\\\/7KuhsEoMJcXi+3t\\\\\\\\\\\\\\\/+oVe4K5vico6TupVt\\\\\\\\\\\\\\\/FPewP7xiZhxUotLjtm4HvegcPhQvZIAxtW+6G+44Sa4TEJpfaiNaecNLqEJfumsRK\\\\\\\\\\\\\\\/Bv+4fxiANyghLEpIfrccWI7LTnxuaNDE9ucfZbYGF6BOoeu5+L1jYGd5JI\\\\\\\\\\\\\\\/R+syhlazt0YDCxpKjQT0qlznTOOhBtwmHlclMhX6M7NpZZJQBvCa4QsbCF62sLxYUwX6Mto8Ya4JTbBx6VqB8sUYOnahz6XSheKfq6mNgWZe+HlsUCnenp6oTpJpe0Hm2dELZ6JGN0Pac95gjY7yDMny5poVlJLQQcOPMa1wsSj0K4+pgGsoavEE0D+OK4W\\\\\\\\\\\\\\\/aUZRBI43Su2ZThk8L\\\\\\\\\\\\\\\/hCkDgv84+ywiu0javNO4Up6tLU6vGNqtWI0kkYv9bMec77jnmPpVzCdOWjhBSWAo3QiysGkuJcJecIMnMm8ZbC98mTZ7UsNNRlWszCveVJZm3XBwe73ACOHneZs8W4w5OKPfjTV9l8o1gv3FN1lcCHPTFCfm1nVtscMTESKzab\\\\\\\\\\\\\\\/Od+yej4PaicTNc7RLUijErYYW8TInlbkHd+NJSZdOhi8JuxX\\\\\\\\\\\\\\\/ZEZtrwmpYKB5\\\\\\\\\\\\\\\/NuS+fldsUUBcb4xPd2KBhlZYsINznd62re8mHqHs7v8J\\\\\\\\\\\\\\\/oZ4d+AVGo2IYwz6+0g5xzuQYdOGcXChheOl9NkK3zkcN1LejZ4nOSVn7KOUEsBf\\\\\\\\\\\\\\\/S\\\\\\\\\\\\\\\/eGzPrU+attxKiPsf0jEfObGS\\\\\\\\\\\\\\\/fF4U+UMuOV8YRPCjgfKTLkFw3erTk1gO6\\\\\\\\\\\\\\\/OLmk\\\\\\\\\\\\\\\/EPsPtpMC1V1YjbH4g8mMhasX2Va619TGeyxU5kRnUCkggE5YpbHqv+EhNBueTX82s+0e1QIaH\\\\\\\\\\\\\\\/oVq45\\\\\\\\\\\\\\\/0CSC4PMFNrlvpSTQdFleNr4AEQYuOfahgB8MIeI8BgVdH8LF7yK77aG6qOKo9X+E2CZeydDhsuS8JaT7QByRjKYY9e6pK6rF7LSjeWFwCAe4b7iuCVeeswfEb6QAZPklpAPaaV6XAtWtTZMVHQlzCzj4QgPai\\\\\\\\\\\\\\\/dV48TjfAdud5vuUNdLT+c4qSu37xpO564h093RoXOqXILC3Hzq87REb08hRIeVt79PS2HeGctB0NegbXcAxrhFmgISi0I2vIOaw0vbhpw3wQdzqQT2RqstRyATwwPxxxRXuEBr1XzlnhWHdc6MPm6CXeVsdTZYRh0dbe1a8xoEHxkhB2wkPkmQfB9GcKJWkby0Eg54z9kFf7Da\\\\\\\\\\\\\\\/tQftND1FjoZrZd5HB3O9FZTnK9WtI+TvIuH5tUBeYCoMMtthWrcg5nyxoUUfz3x6XaKHMOCxPK6Hjf8FKn3P5CTt47+ird4fhtKXFZsTkAAhI+cbV2yBZ5bHuKuvju4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00229wRtXzF+SvZEUqjDfy1hqA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a403bdfd041555a56c1d424233e6bbcfa23fd7fe998debd59f0278c982873630\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1234.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1234.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1121\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1121\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1121\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}