{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022HcKCpbLzW7TlT+fmgvu1GUilKt22sq5yFx0rEOdWmCvk53G0B\\\\\\\\\\\\\\\/Php5SLwx\\\\\\\\\\\\\\\/F9QXj\\\\\\\\\\\\\\\/K5Z+KQ2n0Co+J2V0elebJiZd\\\\\\\\\\\\\\\/VYIBNyJCI1kJ+yCzAyhtk02+GWuxjH7LW7oUWfN8ZP2yLTn8DCHzzLvkxa8EAdh4ikVmxPmil4h8TAAWzQtoPSwGyo0bK+JIIyHx2wkXLCnkmKpEl5ReBlMYaxvWiDAlzggjrT6ATYxMuVhi3HmiJ3DYirIbAX8Rcsn8vn2GNmBQrnzyzPtYDDCw7ZoLNVJo+vPRJtIliF7pAbkHMerEY\\\\\\\\\\\\\\\/HQfsO22jCFMmpQ7N3XfBHPDnIl1W13RfodONXCpHV74Swt57lI0oZ4RImh9EubuyBiYIvg52qZSSzDJgFZilZkKzp2Tv6nDnlwWqQBgUq5VEsTwrEj4744UgNnIw\\\\\\\\\\\\\\\/r5sFJFsh0d4mX29qBWEHP5QtX0WpAZu1LOmn30bWFZeF2VSgM1rHsLB4zpmgG00ZH+JRG0ZR1DRo10Rr00HRCZsneXqZzOU\\\\\\\\\\\\\\\/7BA3HtmyMpq1KPviwRXWQ4CtL0Ul+E0pakVDDQRWNYYNNyZxYQ2W4r+VOCeIAiv\\\\\\\\\\\\\\\/f0v12GEc2PIgstN\\\\\\\\\\\\\\\/cOByPCsp7oBY0p4K1Dk80UIk\\\\\\\\\\\\\\\/fNfAYF8I\\\\\\\\\\\\\\\/RCLkhGZTigM8I8HpNO3CfmNAJDwl5dR2lNhQUS6q4PFwcI1OZw0qQeFAWDOR8c3uPZ2ywG5MZ7nhYYcwD5LTH8QcpNq6XERLl9oAvUg9juOFB1QSJatXXtxOEC4d3PPyAWB+RUZxLFkJoLRcLzlVMWwrxtCxiLyMqcjK+dkTEi5MmRSYR9iizZE5RG9R4ESFiSE3Bn9t7XBa9jZTn17p27Kb7q7c9huJjCERmkb2T2nWTmsD9kGfflFRLnDaskx1NnMrHPJz+PgnPXGSKPEqqe5wc0gu0zhB\\\\\\\\\\\\\\\/1kbwFw7c2DQwMjuibnHMu9mvGg1gZtUs0XmOxZyBP6FUzhadE03GYKCSi9gn3mAK7+SGVUDXq2fOM3oFz+gBvZiFQPlVDMnm+U0WoL93nvrjqZuef3+d4PXQ7+w7SU4kXYuBiSP4YYzlrUkXTIYxobX\\\\\\\\\\\\\\\/mSYIS123meJeLEotsOh+bvCvx64CyufioRXAKAV56hYntJobimjvgxWOSaj0\\\\\\\\\\\\\\\/abJ9hTYnAezP8coar1axX9IlKoM5ZeI\\\\\\\\\\\\\\\/+t4sG\\\\\\\\\\\\\\\/oO16PGX2OsPDStSReBTlIQg9SoFJqAkyAH4cQ\\\\\\\\\\\\\\\/lWqM7NuNufupk8laeFZtr+CGml3xJ8L2NjyivHMeq2v4LxPD275uTs3oaDmZMVnh9lxsPsml1H0Jn\\\\\\\\\\\\\\\/wFae60++bxV2gcLLQwOAUHrSQsWtud1H6OB03h4KJgpOLRdrK7fN003TOn8xSy\\\\\\\\\\\\\\\/XNji73doRsGMet+TVYBib4t0qFlaeKSY\\\\\\\\\\\\\\\/A\\\\\\\\\\\\\\\/4Ra23\\\\\\\\\\\\\\\/iqYWw5+OP1MrYqQJQuCHWCe5G\\\\\\\\\\\\\\\/WLy1MwwK\\\\\\\\\\\\\\\/V+O0ycRr+H9O7xj5gUDEUw1g6UHbE5CndDJ\\\\\\\\\\\\\\\/BQzzpcoSgj\\\\\\\\\\\\\\\/9sIVCsYN+Qx47w+lEVHN1kTZOEuDXhLnoBSx3dF7JIEXrL0UBcV+aJo3TVUY6\\\\\\\\\\\\\\\/NJIlnmalkdxqSrFKq+9tyI\\\\\\\\\\\\\\\/wuMncgrMIFziMi8qG5+yPS57jCXDzeaS11+l86HchERWNSQBSttrOzcKYBYvGtMZCULpwBjmbT\\\\\\\\\\\\\\\/mNZDFXbh6lrDCz7RtNyvespYknkcgXJa7+pW31P8cuwRhMCKV+OhWJcZHD8te8sInARXhvHhHH33DntV\\\\\\\\\\\\\\\/HwxQCCpFRxnravt07DM6vH7Q97Of+2Qk0I\\\\\\\\\\\\\\\/8fJQOJK1EziJoFvevQuKl0YLN\\\\\\\\\\\\\\\/BeuO3JU37tkdY8TvwUSJuBfXO43e8VcGbcnscsEaZLwGPn88bkZJGb3xA34ZMREvNJxL5DQHZxDmWL7UeESMraGIZ6VjjkaRg+mf4OOQSuHPy57vX\\\\\\\\\\\\\\\/DQN\\\\\\\\\\\\\\\/b4d\\\\\\\\\\\\\\\/faOO\\\\\\\\\\\\\\\/WSXJ07c59ghw2aQIJIms9pu8Tcz\\\\\\\\\\\\\\\/D3nvXe75NMOdZL06RDsy9uSikxRCDamUMKjILF8LNKeYvjtSaB2Z1jjPTxSGxfwBENCwU+GZ+92df943vQENcRnZW3QcZBn4SViAV50\\\\\\\\\\\\\\\/ZU9h2o7DvaxFRMfVIfV9VVNjZQIIKKMlCTJYKnLxPjX+zJ11+C43X4vkT0caSW5yFkxEpczcMeTEJ7GkjoTbYCRRP4ewQVz+Ug3ZeWZkL75Kh7GjM1kZK7shEV\\\\\\\\\\\\\\\/pk7sJeOrO5RpWC2OUV8DBVaYrshEzRDMeU4miTtz40YY9cgMUsugoDbu5wpJsttFBhnx7HedaWkLvF+\\\\\\\\\\\\\\\/IIxt5lXbk+1X\\\\\\\\\\\\\\\/veaVi9SR55oGVGxyKYL6WNVgFtK81fteqyBN8YRogtHaIHhcdyPa3tqcnAEVOp6jVXA5GwpSMCxsz97fsps6WelPqE+ffB8Joo18vudnWloC5Wd\\\\\\\\\\\\\\\/MBJbioY7fR+FIXrRk8NCO\\\\\\\\\\\\\\\/HC+v9tfDlShrB\\\\\\\\\\\\\\\/UZ95bsqrsepd8NQRnMBNpykrI8X3Kf4Gf7\\\\\\\\\\\\\\\/zCMcBHLQgMJNFsY10w7K1hSuP2sSD5C7lyGPYRbDAkAv8xhjpZJYZISRs6YLaTvsPua7Jvqw31m+c74359zrdIhdzyC0Ta32aQipiD3agt9Vm34U4zsVxmBSvcUgBFu6I+VVSbsmnVOiJ8kojibfXFzAAH6qbQ\\\\\\\\\\\\\\\/S3A=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ds\\\\\\\\\\\\\\\/IhvFrEbDEW2w9+Uz+oA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002211345a3980f4d520e1f9ae63073b3191e27ce54189027cf8b7340db18a8f7c56\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1651.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1651.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1487\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1487\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1487\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}