{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gS17TD9+v1KkvoQFr9D8iJToOP3BKxE5NrQzB2fEm6AlOaKMdGJUTTyfVIjZY9327Ci5X9AZLJX+wCOjF0kACAs9MU2o7GSCnEZH0GCQ3cnEPZc7W+doSvNXXq2aj4uTce7JMeQUK7m4vxa5VV8yNjMPrmyWv0iE\\\\\\\\\\\\\\\/6oE5VMuHQ7H5oGH9xdZfLIY1hZH7H8VMgaPI6\\\\\\\\\\\\\\\/KZLp2S\\\\\\\\\\\\\\\/roof6f9rLab7xI7LslnKEb66kUmXPdiGwooRGSgmYn1EU66wThizk4\\\\\\\\\\\\\\\/C7gGw8CPwKftjwAlm\\\\\\\\\\\\\\\/LuXkm46MD0aEE0QlvPPnOOoYlbxBYy7dhL7\\\\\\\\\\\\\\\/JHXDeKok7+A22rS6pmjiRcuavqNB5hqov\\\\\\\\\\\\\\\/9\\\\\\\\\\\\\\\/imzKyMD1Ddmq5sEOqEH75CF+UNytPlWF2px1BOWSyh929riP7OcQYL+aTDgS2G\\\\\\\\\\\\\\\/TnPOYn80XhNNAXPjmUkMr1JSCtSQk11vjX0e3dRKnckb5icWXgG7pUKIY+QyQfLuzVqKBrXl9ug3qddQ\\\\\\\\\\\\\\\/AbybaayWMIsTm3tIbUUgKTPtV0xZC4vz\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/T9Lnl2SGwwtnJ23SXj77IVU\\\\\\\\\\\\\\\/E2gy8ZKOmAMrAg8JBax6KXqbrf6UNWxtixe9+1UjkByNUiYf+uG4+8byto0VCFeaMupaxjfiWb7VAzz3nFrgE11aJoeli1YlVEv9Fc1gSDQMur9oaddY7xH5L8xLoO6ocCgGJI3t34YaSGAlqXmaMEgjHsu62sV8YtzVHJPwK4bL76H1E7OuJsThHoBqlmlCCJbFtlbakTsLx\\\\\\\\\\\\\\\/QPU7EiJKlTn3uYkYd7sGEe2G3cmd4PBYOhwP+HOxbDCGn5hcp6nB2QFlqQ26kX2zQRhyDSiSuD7ScTEAp169v4DBjO3iteP77CitVDc6taGGUVYAPZo6ra2fwbqU+b7eg5E9XYM+J+vrt89GQJ7KonueNJ9C8kIMGKL07ukAQ+Xbj5wkcw1Z9Bg\\\\\\\\\\\\\\\/SG6YqKauSVA5sl2vz+WVdWBoW9GBdOY7ApXB+Iat6pXR5N2jqfqUudgrNS2cMclqY4RTLu5Znj1uZsVyhvZWMpz8XM6H7bbWZTIP3P0aYv\\\\\\\\\\\\\\\/C2wHQ62zLOhLrndsof9RBS5cy+4N50lWXvZ9pvEXWiBN\\\\\\\\\\\\\\\/qtAE3Jwt3OoWFCxFJX77Bpkjxjtm5LvKRPpLD2kql2ljlPSzbjz1KVaCP30AsGWzvUq+qPy4Bo9bZA+VXtYRSVkgi8jt4Q6Gsi8VKbqdNWKlPsgnRFQ\\\\\\\\\\\\\\\/w0lENWKagk\\\\\\\\\\\\\\\/yiY5w2yijgJLHEXdkHbUdkFBssnhPnbgelaaDhB84wtc7drf65vEJYmqtZY5\\\\\\\\\\\\\\\/8fjXby3lT4RT4QiCRig4QIyze2+XpErm05E8xi\\\\\\\\\\\\\\\/IIYIjIQSj3XnUh+UggDGLmQ2B6CI1XCgVkRZEsemyPfoYr7yfgRSNph0Vxknulf3dUZnCJrS1gMcwXmYhIkKG1urpFLfZ7gZcUR89CemXzGBrBbdykjuNgJtkKhSmvxZQaa\\\\\\\\\\\\\\\/3tYjtC8adHzGBImfk\\\\\\\\\\\\\\\/jOAo7n7caBZ1\\\\\\\\\\\\\\\/71iE79VEoF7ng0\\\\\\\\\\\\\\\/k\\\\\\\\\\\\\\\/+g6DuyD2mFtzptiAWnAiZcQGBK\\\\\\\\\\\\\\\/tbnfuWBe27U90CJAc73WuHqxpE9rwtesgOOtJqGRXrZOw8aXLXpbTzDv5jGOj+wMHTsOKXh6LsZpqxZcR+WUB25U6vKc4RxnEXxKB6+\\\\\\\\\\\\\\\/oLeiGqMche7bFIXm9saNBts3PfNVQU9Tpr0Bg1XdCR4kXR1+9e9j46kJ\\\\\\\\\\\\\\\/7d+ILoOi9frD32F8+Tvf+nc9Pl7xNymN3LE\\\\\\\\\\\\\\\/ifgWg5da46iWSFiMhfqMbBzoB4DM88oCnnTn1DkOvUI+dmQUKW7rGV56UFSy8JVNqro+2H\\\\\\\\\\\\\\\/Ak7cycet2t0qLrrWGJSKGhr+f+rU2KKYpOjxD5mQ7vJlGUaU7Avd6lFoSrXJjvvQT+AouqqlNe1qqNQWgcNvTkyaVHcl5HqGmV4wPMGgwQZDbOHioC4xbxnkOrB8yaPceIZWmmFnfZkC\\\\\\\\\\\\\\\/Y+IJgfhuMLL6Mkhvzj7YlrSn1n3jXWmkh1ELFP3GCHjzUoQJmYWtuZ1V8rwbQGbzcILF1kg4nWtOTtuMvfr6Q1MfsQcvjfj7Fl7NLi09AvQeQnhcUc5l+trCbgj1fOug3pGmZPg9o1XUWpnPukPF7kcZivDimqNm4\\\\\\\\\\\\\\\/nbEwrueQpFOgtAjfXYoDRDtO1qY7G+U0t\\\\\\\\\\\\\\\/oM25qjdlUO8t7UheS13rYWjtXlE0Ti2aS6b8tq9v0Cd14R5HiMwh5rjk+bGOSBhSZ6afA\\\\\\\\\\\\\\\/Q8N96JZ4c9tjVhFM7Cdm3PvAcG7p9aH7JOI7M7ZNcmpQnreinMEa4pS7k1jbXanuXbVWzsTfblxQkCwPSxSBSKI\\\\\\\\\\\\\\\/G0XWbd\\\\\\\\\\\\\\\/D9u7ALBzqcsyz1cWvpekwFEw+ooPNIv+1Lp9jHm77itY\\\\\\\\\\\\\\\/X2hnBfeZQZnxTCkTpHqO2owRG5b2EqbxgLPzVA7OkJg4CKG3j7GfA+38TdwlKmPdr+GArOOZzo3KFOWsrGWGk8xvSj5h8KIvjktbjjHkTo2olmsDa9Ibdhef9BBqKO+kucRMPlGAefpOW5IFcInoWQjVZa9BxBNBf9+kVgkpFwHqDfzBWOs2H3iYSAYxtGTO08IIr5yECX3MhH4fTbfCyZLzwZe5AnNTaJiBuZM5\\\\\\\\\\\\\\\/0yb8V4rnvdbJoBQs5aCkZSbdTo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022y51Q7gtoGkTQlCKp6FLuOg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022af879e4da3209dd257270d0f171cec86ea8607216ddb8036a17ea8118f471ede\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A226.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A226.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0198\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0198\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0198\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}