{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022OuifdWYtnTlPaD91buQbO3GpUwMvzXm3ehlLio0PtBvcex8mKGHkhx5mz\\\\\\\\\\\\\\\/IOCxUoaE83TjT6SaPM9s4CnS2NyFeBoyNEqePn3uV4VaXCQo1AdzD98LE67bNEed\\\\\\\\\\\\\\\/PD1cjDz\\\\\\\\\\\\\\\/T+SBa7Dt6qsy+rgE1OQm0mCpPZV4SEGpaqBcb303oX8s5G\\\\\\\\\\\\\\\/NoGRlJoVMKFV8Auemdl6z9JOWXAp+BwRm6kMIOcJB2toq5jFfj95Rra77JjhPM7QS0f2Ry3omPKQlk+xpwJntRSpSpeeTAitaldeDWYlfSn4d46Am8W6iOmKzy+ObcxU7uz6ZckgIPaDxQ74KQYk8nDArXwvnNpq\\\\\\\\\\\\\\\/FrYLNrepAt0ZFu2qG+8KTfTCz7aYZo2NDZA0CuIkrDGXl\\\\\\\\\\\\\\\/m9IjKbPQ30qQj5nNltDcEeSxsXjbg\\\\\\\\\\\\\\\/1\\\\\\\\\\\\\\\/SwRFmXRlLqoIwWoaBZFDjIs6YNTEG3fxGQA05J7NpPpSyg2yelI\\\\\\\\\\\\\\\/8bEwxjSJtLdsHU2RJWWLJgh71gDMP\\\\\\\\\\\\\\\/D4SqPyaYioJL66t+8PzL8HEuSpuWaTxsMPvscQsb7ltv9j5ci7C\\\\\\\\\\\\\\\/DD2+hgBFl620MPMoE+8B9E6Iu5BcVugR2TddasKVZ7haboSS6+u8mBTzMRfTUCJwRN5YiTDl5ybGzOoviKCyQr1QMch+FxwnOwI27Cwp1ydh2F5fhlea7V6lv3DH3gBRAz7\\\\\\\\\\\\\\\/d2LWuy6\\\\\\\\\\\\\\\/C5sJWUTCFG510tsnGuC2ioRmAnqGrV4RJg1743u8Yg0TOzKmr1utog2ivwgkmGRqhS+LniVk5fJhCkPoHljG4\\\\\\\\\\\\\\\/yEdevxKkDu4xYLZKLj7muxHd\\\\\\\\\\\\\\\/V1Ef3sqejdlcAdhtaxRB2++SPyK\\\\\\\\\\\\\\\/f7Y1yy3xw3vpZuygaOSg8z7W1o0wdbP7hIr1Z2kqLSq8NOkv0kxbOmyJhO1eiUAMbBJ0g+\\\\\\\\\\\\\\\/RSvlRmHnbuy2APs5mMAGIluyB26No1Lbfb0gL1Rm248UnfDKWPPlFpv9j+RVo8yd8IBZ8VnUNemJIwv51iellO4RxsFi27ZgKrfh1WL2pIIquPDqb3NPvMc9KR2Tz7yX+ViqdtspgjI0ppdVcl2FAbYNnFmD11PX1m+odiKKNlv+qcP+8f2tRtm3fH4UD2W2UGhIkCbi5F\\\\\\\\\\\\\\\/63dSY\\\\\\\\\\\\\\\/E44V7YXEvP2ZcbzsofCAYCEKqFTAvwld7H1Fb4yHFDaok5YQvIx+VH3dxTGnc9xCjUL5QRpxWNT06YdeH2zBrPSSaQjcsoavLyJjUvalbIcUfjvs5iFkETmAnRf13wIXS9rjLsRvB4cp0OerVBBBUJPqSPk8aPQGL+LXyyTa690U0dsQ0kfkp6LyRf8uLULZ37eevb+CwsHi0ibb\\\\\\\\\\\\\\\/C8wOuDB\\\\\\\\\\\\\\\/l5f1OvKLQ0EXDXWVoQduJZOz\\\\\\\\\\\\\\\/zHlnKeC2Iqr9yuyV9z19anJI1iJF56KUVOuZxHzZo\\\\\\\\\\\\\\\/FbHkMHSKHOusBm9ITtAi8F\\\\\\\\\\\\\\\/doylYgVKkemWPdHZKB3+7KKyAZsJLBoMyX8F3DgCX+zNOAl0tDjDW4p3M9w2aJQX+Y+UPZ6DfK2fyFf4TqoT41HCoJKeRED\\\\\\\\\\\\\\\/tMhej6b+rAYw4ZClfcfvdv1ePuEMLI5zDf\\\\\\\\\\\\\\\/3irjrzMtsUv80QOc7LcVhrnfrfe7vs8QP7Dt5vFqXFveRExx9Bf4IeO+Msw\\\\\\\\\\\\\\\/iXmwQZg\\\\\\\\\\\\\\\/zH0KJfL\\\\\\\\\\\\\\\/8uqZIZ4zgIha\\\\\\\\\\\\\\\/i4\\\\\\\\\\\\\\\/cJZZeP7Rz\\\\\\\\\\\\\\\/WpHOfpD9KGuQPoEh2Y0a+GYmEdHetiVJeDjyBwVfWd0BC736TIeuCp+CvrgMLAFDp0MsjZTGPFW2MaXKXLAmP++ckjr8RtFv9WmGy7Nk20eTqr8JwV6CoGy5DfMV+YjDCKnLvkem4JP5Qnk6TMKnB3pJI39nxuCUkLV4oI3SDt31Qm+a\\\\\\\\\\\\\\\/h91IAX0a6MseuDuj1xLHdRDXGh\\\\\\\\\\\\\\\/WNF6gVIOZIswGWwJfsjlYQPGOX0yK04w5cmluscfOb7dzTMlWZZBK83a4rZHPX+7OjX2xiM5VC2GUJ1a7M9oA4TpbOq8F5Alf0O2TUo0qUPObvA6J9FGxFg5QfuznJQUcRLC1KCBQATi5nNeqhWcKuP6x+gJZElFXmPSqHEWEDcRB3qvGny+cVwLlsxcUJi4dY2nhbOCVqNe3nQ21ULrN2n0g6ii2NiIL3+sG+0hke6fl6YWgcjTAEP\\\\\\\\\\\\\\\/ZB1nhydrOwYc4U5Tr5yXXGLANdhoh4UetTzSdKz2pP7ibR1a5cirn5ImEQbu7bE\\\\\\\\\\\\\\\/ELyy6OL+ERz7t3fZajX\\\\\\\\\\\\\\\/7AWYswgrn4O9RBPLAvvMzqsz6yQQ7ITBtK2wJBF2FeCvDkaRB+maYku+ED7VFK6V9DPIo1w7EUEe3lPUm+ifkR0i2wFo2O9opRxBx+WfMv37R\\\\\\\\\\\\\\\/wsHXPGzfcafN9kBDmTHpzubw3xiaekzmaIEZpR52jenoHt5kjYWZ6n2OkXY8S6mAwQAguHxtejLfulGmV6tc4YPQL7VJWzj\\\\\\\\\\\\\\\/lg2vXqXvtnqz1LKyWehAkM7qdiDyEFflGY8U3YXlWDlb\\\\\\\\\\\\\\\/MF08v\\\\\\\\\\\\\\\/ZfSmG7OWBRtaPhU7WnzlxJ6whVpMen+yzACuq1abwVoZ4KE+7p90kHgeG6uQTdt+qTWGbsF8htzLgnsm3m9dEpX3VFB5M5r2AqHOeH\\\\\\\\\\\\\\\/o8Pv3K7T7b2a\\\\\\\\\\\\\\\/2fER551jRIs1Kw7nT2pDgTNISY+d1ZkhWiCzyrqdPlXo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00227sKKEDygO9eK\\\\\\\\\\\\\\\/YKfoWYx6Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226aee9e11894a9abe807388c3360f5ac035e0af768a04a7382b147eec16bbd87a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1102.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1102.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0995\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0995\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0995\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}