{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022PeXgs2tT6eNGHhhRMYD5j+KvVw8ijr0inP\\\\\\\\\\\\\\\/2ODOiPAcDBF9nbmeLZr4sqk6ov84IjlJZTWQ+ofzWkgpHCTmKce6Zix9sjQyi\\\\\\\\\\\\\\\/sNAw4QTT3OkioEzCJsvHDQnCcXAKGlQ3SypRPTFq3UKF8WbyyOBKE\\\\\\\\\\\\\\\/LwUOWZwGFNunc0V1eoyBOkrhY78KCbm\\\\\\\\\\\\\\\/Dmh70kyhrWlLGIKb\\\\\\\\\\\\\\\/zJj+fERMgEzPjK7\\\\\\\\\\\\\\\/Oe0uPfVsY0E2CGuDE4QPEf9Dg5seQPmR53XdbO68oduvs0ep1Zr6Z1lApgrzKOCdoPfg\\\\\\\\\\\\\\\/U8cbZjGE1abMSdhNEA3x1PiE3jYtPV8xKYfzM2S0ZhjgiIqaFzeN5lzavMqW37sG2BvTG7+KKvD5hRsl2MDolHJ4etPvcK3bQck0b3NUG+K5jyQJjAb00pbuV384VOvjMOzV1pTpy2ab4E+xhjDrWXAJObcjEaHwzUN\\\\\\\\\\\\\\\/yvRPzf1GKuBU+RgPLx+TfkJMZ+ZVwWYz0JGk718upZemoiEJYZzHUxWi+DrC22HyywGoxgV95dm90KttWiIpNEs0HlydNADH3vcum9dfibkA+tbzSscGhZVnshFDKxOBAuT9nElBmtw9tuwxGMx2FaJuaoyiVn0QNXLs+VJirIWx6LmQ5O86qnC45TuG9ORatoLn9dM37vRLhFXQnC9bbhVKmjUOvW7OraXYM1z9dcYXGHxqm6HGeAoTm60d7NK8h3tB9EbsMt3v90l9DLSaZradV20Ropa\\\\\\\\\\\\\\\/ErH7rkmkc1exq48xv+rSNrYOQGeA2smCMupENQuKnIjNxX4e6oV+nGkBYFXvilGqCdZ59vdeqDryqgt4eU8p2V7mQJMw6SmbUPvCdpozTRXGpCBNXILhjmdLJ0w6QrYLUIQwBwqmBKg4nqhSU7YjMGuBzjqIQwWzcKOg3p9z2exyL9J15wkUGdoLFt8bu2HGF\\\\\\\\\\\\\\\/IhTqIwVHluFjT70Cg7FL1xiYji17g8OiYXBeOfCbvRysVFmaylVZgf\\\\\\\\\\\\\\\/f1TwJw0M5GZA6\\\\\\\\\\\\\\\/DQhqoTTbmF2xT69mo9pb504Nj3VvvQ9K46X2PeyE0txdMz6Lmi6+dtn9rmgWbAj30HLqa41GMP29\\\\\\\\\\\\\\\/H8zupGFjuoZ3+kRLScDGkSuQ3\\\\\\\\\\\\\\\/4c26IKaNkvnNCVn0+7CLJB3CLR\\\\\\\\\\\\\\\/KA6uMcfEgOCyfMp+BCyucqr6kl8oXRpwsxa8C4qi+ZuBkJadrwKagdBHqsJ3qM3GMIFZqO0f\\\\\\\\\\\\\\\/oSSxGXKgCS3Xnt2aAE8BRNFEUxd2K3k9VjDy6HF3EcmZ2WPw0l7H4KIIYUe4lnuYpgH0P8frSsKVnTGPwMv92FxYAGOnVLM19w34u1+D0ADeVQD06SRJQ0vCDiq0pltJYjby88bO2C8HY+3O16LjLHJ+g8C2YwVqolLUMV4s2UJTg+kBTBle082x6K5wd7PXkwfvN1+uckBJaIpR4qKSzq3w0RKeaTN0r4jYStfhI5d\\\\\\\\\\\\\\\/xYEojdWtHC9G4XrqaK9Fw+7XpVe0F84N7bQY1JJUlzf96LK3opp6ABUoyUCIw9RuUWLF8RgMZ9MRWedfSnTbEh4yyyx79mVSiosWh2jW\\\\\\\\\\\\\\\/9mo9qIzUnz6B+4nC4RRcocxzYhg7zlEwclGU4QRqYikU3kUUZfG32YsAWdnqLoYi7NAi4q0929AvI9fz18or\\\\\\\\\\\\\\\/ocYDr2kauvAZoQV62eR5XQxeAx1x9AQKxobXKyNGgV8Urf9pbuprP\\\\\\\\\\\\\\\/fh+euDdxkgNnU3WOMTXkB0Vscu+hHBfYg69gUWeCwkj+i6hxKiEOyUpDrB3xQHLCCoXiaihlyAoPw69NMc6HVOhXsqEktEbpot5XmXW1RTxg9x4vzUvnbfNe1QS9t\\\\\\\\\\\\\\\/V\\\\\\\\\\\\\\\/I\\\\\\\\\\\\\\\/QSWq2Vfjv3jOFOuDZJEh58mi7Dsc1PilJnMjXfOS9L2HHQsxlpgD96HXXp30puqlZnA25nPm1u+XoJP\\\\\\\\\\\\\\\/s1ozyX6IeukcsxU54gXRrMwGVDEAaqXcTjaEtY\\\\\\\\\\\\\\\/ziwXRYaDlTElgs85UsMkjqZUF4HgM8ybLRXErcui\\\\\\\\\\\\\\\/+hypDMmCZ7N0h3E1XGo8Ejrn052zSrUAb20nd96d1eC675lLUfuH58OQWaanc9RevlKUY9smK8PX8XF7nqlz4pDUEy6pZVfIe2XKHnVATETYBPKbUvtTcT1uaQDXttsP\\\\\\\\\\\\\\\/qprq\\\\\\\\\\\\\\\/9XMWylAGDfn1pViVsjSsfY2gHILg49951bk1geRDQn\\\\\\\\\\\\\\\/EKrnXbDU4fBDskUBcheOw7H8OQd6gC27sAeAj8KZszSmm\\\\\\\\\\\\\\\/xxc0IxpdvJOhL7cU+6gEHMUXnA1uSijFiL+w0isz6eF1ByN\\\\\\\\\\\\\\\/XPzyZ3cYpwc9Dcpvbq5RB\\\\\\\\\\\\\\\/73jHuOEvunJv0BErj\\\\\\\\\\\\\\\/2s6YQDu05pSB5xvNAdptEUh92N7iZy7zBe7xPXo81rBJ9gXawygbA\\\\\\\\\\\\\\\/vhbuwJklHJCyOlCYsDS3QY67t9eil0EGSVvzJbPh+CHjdJ\\\\\\\\\\\\\\\/mCx66GzocgnA7HQwAgQAEASKpF5F3d3jOBTHHkl3N+BZCji\\\\\\\\\\\\\\\/O3fPRElN7l6VyZuhw1MT\\\\\\\\\\\\\\\/T78n2pc6K2QlD0xwhQNc15NVR8U7YLVn9usjpZXez0RNDsNsVoZ9I9hOI0qeoNOlXeuJqIvmNMeTif2C0KlQpdZ00gsFQW9cjJWbPIGtyWi7efszZXL+PJy0BZZimi+\\\\\\\\\\\\\\\/n0D47liNyDTPQcfrenoz4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022lhwheWl3LqpN\\\\\\\\\\\\\\\/zVvIER+yQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d0a3dac673e94dbd7a69cc14e1966aa66890b2d42e3dc448e5d1e04e7a17ab92\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A912.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A912.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0814\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0814\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0814\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}