{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022mtDAtvWQRlDV8Q42+t5tnOlBY6j8XGyM12mY5ddlES+3XWKa216pLnnaXuFwZTe\\\\\\\\\\\\\\\/Ka54LYl4TBbIkKMUk2Xso6OvSHI599Z3yvVbUhjqAm\\\\\\\\\\\\\\\/Qk57LrHHcJbNHHP8tnU8jWI1ZteO7Bj5gnwLN5JcZu9nUKRPLsQQfzfQ0ErFRHW6P23qIMdNY0onw6zHPxeS2TeySptUQv8TpV2vPO\\\\\\\\\\\\\\\/lFpWg0CO4GWr5H851NxkEgkE1g\\\\\\\\\\\\\\\/VqBTWp28pIeba21crqJ5hhzPye4V9GTBH1zxuBjbQYDCYVlg2K9VSegB1cLPQJsXt+Ea1mW5PNW5HGxumKVNbs98Y92BAYNLgArTPecZcuTM26QVaW5VnOwA0w04DvjcatCR9GHa6RfhCjT+UOLZzRE2+MOGIQHKXwcZrh5hesRWj2otbfcrft9V2z0x7SFA8H4u7hEV\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/1\\\\\\\\\\\\\\\/7y9wRy1b+ek4GWlSR28gJNo5Gst6fR4IIhkyrYrYNAAb\\\\\\\\\\\\\\\/nlGMMbk458+UOk0KyIfZyLmAP9mGvhJ8OjTc6TRJ6DtZcskni8q9WkcLaIMUpDYRQnxBRTEudYcZU+sc0D\\\\\\\\\\\\\\\/RvAVhz9f0MMOtOc1XVeegQes6SBi4z50a\\\\\\\\\\\\\\\/9j+6Ivu\\\\\\\\\\\\\\\/P0\\\\\\\\\\\\\\\/U65x\\\\\\\\\\\\\\\/LsizM7xObS0G6soSkhW3O2V4N4gdbyiFvK4VcAzxDkPL\\\\\\\\\\\\\\\/M2nxg5W2fFehhCk+zPn0+2K+vTaOiZgusz2HGyNRJpXQomIzwUaJucQ63Lal0DotjMnomtC3Qz2tm79ZBR3Ky+xZKbvEB+eU7H1WstPEJ8twzcl5T\\\\\\\\\\\\\\\/Da5rdEdePE+k1LB5pBqOK52Bj5k47QwYCidJJhoT4zSecmJHQXdJlIeiX2\\\\\\\\\\\\\\\/Ln9\\\\\\\\\\\\\\\/whplDP8UYqUj2mfraHKRlr968YBRHmKhkSTF9yLDkQ2pksOshxV3s7SYhqAHzUjim\\\\\\\\\\\\\\\/XwehC2JvLavBUOoTP592D\\\\\\\\\\\\\\\/MWVh1pEfxVwT4vfO3ObeApvjZ+BYgWZM4D2RdJtSxKLhd4DG2bHGcrIOwOoz0U0ZsWKGDzILejHiX7hx7vJKNxaKZMnbpNNNUFhugbAx8zFW+wTrSmsHHp5sJv173UXlx2Mh5oojZrg4Sx85kq9PzVw7yR3OnSquvossZBN0+xKx4jUJHE3b\\\\\\\\\\\\\\\/udN94aMz7cgN9ANwNEn5tjcpDjkApQ82dZf7VZVxolyO+gmMBQF5fUT\\\\\\\\\\\\\\\/OQ9gAP9vx+a0TMp\\\\\\\\\\\\\\\/wakkFNL2HKNxqLtCRD47kQ9dnSnvVwDrXxrk25Ckair3y0lU5GZOGto6726LudoBttpDbFXMYYy0sVBBA2Dn\\\\\\\\\\\\\\\/581Cy2OtNFNJpTtje9NKSM\\\\\\\\\\\\\\\/3B9hinhPMkLKyl6mACqFeXsOFkFhhw5h5ndFlUJre1APcP3HY\\\\\\\\\\\\\\\/RtPc6ffiJ6eepQiUgpJALNGRMe+kdX4YkiCEe7ooQbzC9snxiK\\\\\\\\\\\\\\\/mIWrG\\\\\\\\\\\\\\\/ZoBwN7PvJ\\\\\\\\\\\\\\\/7kftRFHCtMew\\\\\\\\\\\\\\\/1HE4LnoLQOC6E9OVQ\\\\\\\\\\\\\\\/REnpePCS\\\\\\\\\\\\\\\/yIyOXvvEn\\\\\\\\\\\\\\\/p6AKUI+h3BNeZ9\\\\\\\\\\\\\\\/THsmdDQ67uFZ3Fm5cXUHnVOfSGOKcKPvbtoK8SBQpaMNosTCahPBQBxSAPA1EVj9BTno2SlL5Bmarm8jP5nOFYNJDP8Z78n\\\\\\\\\\\\\\\/jhxWVNEJGKL+D3tv0IzATpBJ48\\\\\\\\\\\\\\\/mimQTmnWi90VP7HqCjDnyRnHrdts9a9eMp3hjEqj\\\\\\\\\\\\\\\/WnrOhYtlU9+Zv5iU8p5+4qUk8m65WMRcQ9wO+btAvWOYw\\\\\\\\\\\\\\\/t5NGHEOqOqYs1t7Py1CdP2k4ZUuQiYUSSXjllyORtFRtQMI+oVj9+OA3pLdr0nnQGLH0ZIadT94Ajq8fcZqlWTdXaz2NAp+dXByLQWnohLVqIhx3rCLL3P\\\\\\\\\\\\\\\/E4qGFvhKs3jzMx21odst4H+i+CimsHtwx51JW1zm\\\\\\\\\\\\\\\/dG4jS5WbrfjWcKwGZlIUYiP0EmpX0335XNT\\\\\\\\\\\\\\\/zb6odINqBpBGrchonxbsS7t+Ds6XCJJIUymT+IV1o9Nk1fa64eU+WaXsxN9nbU5RC+JLD61GmRynDLmRy3FnfApywaLDEI8TX9JdGEzA7UFx3e+4GL4mosDKJ2GfC8Lz3TBMuB+nvWYTfsiOg7H1UR65VWZFUopjGsZKr36MQyzlB65mNMYp+gM8DTEQF3eC3pmfx5z0OW2LBUSbXXEfjJHDJfSUYkA5uUeeuSKm8JOkiC0mqNSZKrBD6nT8vWfYfN5DumnfxduUk09ja+eLRklV1uobs6QCcav7dRMMAso6aR31Q5ZxuhCXtsH8JApjmEx+Phzalfz1S9U7yv8yOM6ctvnN4uxFrC8Zi8FlBOO5cd8L0mMxw5lb4jMVMAtvul3OgOFXMJByZRLzxVe1alat3Ij7eLgEhbsSNVLu0nk8854hdFGQm4puYdqTXgi8fW\\\\\\\\\\\\\\\/ltoBGh4MMaERP6\\\\\\\\\\\\\\\/Qjy5FE6XRYpHgXd6v7tTUvYCyJHbw\\\\\\\\\\\\\\\/EN7IA+3n2RrU+MhWkgJqCkV6t33UTF4UC3ou6ADN9E6NvypoM0bUOqmu7hAREdPCKENOexyDf9ZJwAl\\\\\\\\\\\\\\\/6KV0Q0OH7\\\\\\\\\\\\\\\/b\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/5bEd85keMaceuSjpoVQIqPZwxfX3w0UEWloyaENwZ1r2ks6ETrOAiBEJ7WNiVze1clHfBTJkwnwgLf+2bIOj9ewGq735dfgi83XXVNmuiNGyVYMEBvLnYzuQyYc0Byzm\\\\\\\\\\\\\\\/4CRllnY=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022f7BBAQR3S55Q9LvJ4XFDQg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002227addc1f6a46f49d0cf6efbd841ae7636ab2dc7163971b545df691177520bf58\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1494.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1494.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1340\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1340\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1340\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}