{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022++NPIbqOu8AlltyjvjJb7VFThNsblGs\\\\\\\\\\\\\\\/+VOwaZO9thDPl88rNk6jk9aYK168v3Kbn13\\\\\\\\\\\\\\\/fdx3ellNVu9kf1PDxYaUcxXyKuwtktO4SpLPw6IKHRbnBv6Ve7FF4TEhvSAJsLmJwivqC+fNfWJQNsueA4aO7K\\\\\\\\\\\\\\\/3WmYQ9WE+x8h8z5WRSwhqN41kdo65VAQsOMcFRSsJJHnZLBCX8awraNsTkVre3lnI+k5JMeG5Cecb\\\\\\\\\\\\\\\/6NsRL+lGDUdx05Q\\\\\\\\\\\\\\\/fJRJZo2RiZ\\\\\\\\\\\\\\\/f8Qk5DCK6uO7WrdSLkLgMHVtQvy00zYTEG2pitlPcRW\\\\\\\\\\\\\\\/6pi2Kj2nODn5ln3Kk9zKddRiHAivmRnfj9N7ioII1olwXd7WLBlfoKg1F+fquOQX9AOwEYRPc3yOOS33agzO7G8OWXVDBbMqc40gkJrrwTOZ84c\\\\\\\\\\\\\\\/OViMQGZeEga6KumPWYj7f6agyOr07TVUj4cYUEp4d1jIMDthZ\\\\\\\\\\\\\\\/7Zr5VYrByQGxMfn2MFpkwTJV7iqaisZNXhn5A8Z78ZQCsv7fULzcZqeoV2s1mOzPOTZ1NbtYr9DORlTwpSikSW7k1cLbdySaeSW+zom\\\\\\\\\\\\\\\/71gwFU4CXjfFP7UXfTKSdW96dOKkSG+\\\\\\\\\\\\\\\/3JEB1su2zHTkHE\\\\\\\\\\\\\\\/sfCCbx2Ar02Scqhjo5qPw3F\\\\\\\\\\\\\\\/1qC9S8ezru09HwmKMxR67432JIYnU8s53ZPFLerIaj8HHKwjYYztZsJGmZyjbqR\\\\\\\\\\\\\\\/JdUXF6mGqqluTsGJR5Nwmt8prssa05vAIeW3peqXw8Y9xl6C8BXHW55bwy5JGjt2nowGSdcZudpTnSMbiRzf3QwkoS9dF2RGHkBTyoejnLmYjDlty3x4CMAOwPhAVQXkHTlw9HUsVQHR8Y9Y0bWKKp9NR5XGPunrmuBJkHNmkcBi4I1RFyeMzu0gwRdIJQAvYhjXdNUvMwL2N7Lqp7blC7ksQzFxXEEb7XGQr2lJCNV+z4oAKIaTz\\\\\\\\\\\\\\\/tVxeYBMt6wO3sMPcaIDJ34nqFeVBWCLv6xnbVCsea2OZJS9TCyc6y6Bh9H6DvwhH+9DVODyX+9z+a9Uk6FcZjycypQCGyn3rDdSW1z3jyVLmGJAL69rgbCMxPTSsnYC0xe7Dp2w0by85cHriv+CRBrCn+dxmr+lFRMT66Xat4Bezwlt\\\\\\\\\\\\\\\/X3V\\\\\\\\\\\\\\\/r9twQZARSLti0L4\\\\\\\\\\\\\\\/pFuiX+DHHldKP5RQijWR5vQ9dprVevkkShpo7JTQDeGHTcDUgXBzS\\\\\\\\\\\\\\\/Xu\\\\\\\\\\\\\\\/cfUrYZQ5tjdykkasx3hru+vFDEbrAhk0CsL6ugQVGqosbb\\\\\\\\\\\\\\\/s9xJHWKUhAzw9bF+mqAHG1mThe84cYNzN7QpShvgEY9WZ26P9pU7uRzPBBTN4Y0AZ2+qDwdT5SSxa22Uxizk1Woc52ZTU9wtjjv6trGsA7YGtpGyRhmFlbZE14sRUCT3UL7dctRDGSNk7c4tmMMCwAt6Vci3nuHLxo4bGOAzSHYikGk1pXieNjlnPKcPNChXAVoaRefPGvyF6P9Kj8z3NYWlaRCeCveh2L1CL7AhfitcNU5sfunlvIaLOFPWHzV92V8r6SjjZnxeWIFI5mAOtYEO+di6\\\\\\\\\\\\\\\/9aO8vXSPtbELv0GNiTKGk5YPE4\\\\\\\\\\\\\\\/OM1Mjc5rmVpbsLuXvcjNevbt\\\\\\\\\\\\\\\/nqfhSnL1Eil1NMD3gqP00soQIUY2nUK\\\\\\\\\\\\\\\/gHhACY\\\\\\\\\\\\\\\/ouJmR4T5a5Ew1\\\\\\\\\\\\\\\/H9hhXuPf7ACRjDYVwx7ci+xpVE5fYss8fgv\\\\\\\\\\\\\\\/iHPWfwkEqwtlY3jvXaGEN38RehU+NgUaDeUa\\\\\\\\\\\\\\\/Do\\\\\\\\\\\\\\\/ABbaehLVYuc887pIveY6oDOKDyiwgFxllxugsllU0MAXnlgRY0Bv1EhOP1u8y+dR7r76gup92+VT+WzFVBNXMKM9rfjzDhUNAK4nH5mHt3xsfF\\\\\\\\\\\\\\\/jaeO46+g8x+ULn8OgWC97iaA39qGHR6wkC8xWRFUtIeoogR\\\\\\\\\\\\\\\/MVNkcedS138SY8l6SNTJwdTmVURkgMwHUJBV4vnJ2gdRducvpautxFRiB+TvsUeEP6rQXvsmk89vUS1Vnuqfq1elz+EcMOs9YSesGBogqzbii4jLm0B8ko9BJJWOuLqB\\\\\\\\\\\\\\\/q9qy0Z\\\\\\\\\\\\\\\/rVVvjypCslJc9mK8bZutQEH9xMj+8oLDk5wXWpof5nt4KlDr8mFL+KXI8WRwj15YatzRUCFej6Q+irDRIkHliUXOFjZ0ftGOWvvkbh9tiTEZ2xh5wqVy16+AZFwXQL08N8pXKEipJpUDzT+PIGp8TMLlD4UnaNuhlV6HxG8KE\\\\\\\\\\\\\\\/akJuW\\\\\\\\\\\\\\\/1oJHkuKJzfHPYOU3140d\\\\\\\\\\\\\\\/oyV8XQ5VxgEDclHDbWGnnRvkkLiBBKiCnR7izFgl5mtQxEU53pfysRueL3r\\\\\\\\\\\\\\\/m6KPJSrdGl145ZLZ9t7+FdFwD7cYAm4wH9KPuIBBhQuVp9ct\\\\\\\\\\\\\\\/ZtJ40liRGVrL806LlRSSztAAQHacaqzKFt25Hv84XyFsNg3xdNMnvutMbuasRkymb5vEKFRUnfx\\\\\\\\\\\\\\\/o2anCfCRzwwKq+2N\\\\\\\\\\\\\\\/TqJQPNIu7o17yl81OiNu\\\\\\\\\\\\\\\/w6Jp+8MMzIb7c+e\\\\\\\\\\\\\\\/lZjLrIK9szH0qCNeKMe+cZDkCkY2X0FQ869pa2pj4HCL3ShCBuV4ofS8ZWNQqtnwAOW0Mf4wWeolJbvv26pm7DmpQtnNH7W\\\\\\\\\\\\\\\/aLcfIJf4HzsmW4sAedMyMrxpaGReweV5P4EoS9MNQ9QloANanv2W4R0ruhQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022DFevZCokCNkYBDKOMPUTig==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022538b66e1bd8506452de810de04b9dffdc5999b6d758ac7d7a42d9b6b297fd98c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A462.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A462.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0413\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0413\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0413\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}