{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022f15UqWsreOz2WpCIgqqoB35LYyQoQzj3+LWQLZ4xw98p3QnVAcNWDZmhLJHsDWcah4ThzZ\\\\\\\\\\\\\\\/wAA1SxYZn8B6tNBjgSuiInvUdQ+8aQ6TsB7Auxklj1Q3BNgdz6NwFek9lIEMpkTwBFn3Aave0OYeUEzwcCNlb7+qW2asziGlCV6aF\\\\\\\\\\\\\\\/lcGYJlFfOyZ9g\\\\\\\\\\\\\\\/az\\\\\\\\\\\\\\\/EeVY2TGzs0UcdpDw+Eq34PNlrOxauU7Os3oC795m5JSVtuZ0nTrevyZ9LYIKfkY3IPdTJi\\\\\\\\\\\\\\\/BQdERGpWrg3B2CfFHsqVfQkSpI0hYWKfsI8KtWpm9K3nuHA0Fpnj9UO+CdXnF2McFnx0JI7QDXvU67z5vLTKBvkiC8mDrwd8W5E46KK09Tk0yptVJDhtBmXxzUsjPKQD0wA1UGr1C9ErVQimzRUUFLf11m8lvENmROSCeP+pt7BXHmGA4Mmn4vKieLtNZ7QalFxiuhMlCgceTCJq8xV+N0Lcf+egNoLIx9oNsje6hEpCOhfNssuGTHVHHp6IVIUTCARl4wK4MsxoFRpYRBLofcMMLpXLG0jkX2OQr3gAGHn7QV8Wk81uAuA1HN0vMEP\\\\\\\\\\\\\\\/s6fzoMNauRp0CLfknK7+DMUyS9iM8uJiEFIiqsVVblnrXuA1qPUMHVrQgIppQS5oGS5BxnpSm6MSvUp5iqcSWLHu4UuKr4FOIqJXDhsn1Wt79+JNcGYIEGFiTvd80zE\\\\\\\\\\\\\\\/H2f1i536Ey2nNdeRmYMI6b2AbFKsULDYRcpCsaAvwendIQ2tUV\\\\\\\\\\\\\\\/NnDc\\\\\\\\\\\\\\\/9TPcbeZvad\\\\\\\\\\\\\\\/yCrmU23walljnWNwbP\\\\\\\\\\\\\\\/llVfGJ0Y39RAT\\\\\\\\\\\\\\\/ryGZhEO001Bt3tTIZL8wgCJqOH3l99pN8dbJsTNXKQukZGwAf65bWaBw7jGui4mejfDDxT+GB7dJkonHDG27bf+TQz6cGU1TpZVfzJ8yYs\\\\\\\\\\\\\\\/4bih3sU5+rqQHuvcjYoDogNMBArXjd5YaFINlzASxPaOU+sSvwS6h71wjV44eT2S8kWkTc9TsTWKV15uUb2CvyKu\\\\\\\\\\\\\\\/jpkjPQBtZnKzo1mXZvIyMK6F53xGyeq4bgQblrZZRQgnGdTXIQwqldEXmFWYK4wcHEPtBpgRVmzgYXJF5Vbqm\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/iAlN+4oT2myVp9NzYlUWh4wUecFzsaM8n9l+58jfCYTnhgbdXsBLSZVooAG63BMiAixe8MHSulEQokWNGVclA5ay1NZ0jeminT5NlabeU130jGCsokz+ooRrQaphY3FuiacNWKJk65ECttlMY4TL\\\\\\\\\\\\\\\/NupiWQv4s7EZq0a42YjpqOxa4KcydkwGHjv514i1gh508aji8IH1EGil1gdL9K+IGGj1qByAdoo0QLCiok6ufM7bH1bOAt8oif3BO5l4jWVJwm5NXLG6bfFzXzH4h26JCnGLMazdTtq9C33clUdP\\\\\\\\\\\\\\\/DGsBF\\\\\\\\\\\\\\\/Lkip9KjGvzajMmeDrlHEuITLXbW7LLuH8OI0v8LOW3Xu0x6XBVAoKYw8\\\\\\\\\\\\\\\/cUuK+9tUy84AIYwAfD\\\\\\\\\\\\\\\/z8lWFJLwjpI8iiauqVkFvn80UyjA3MutS1J\\\\\\\\\\\\\\\/T3oJGOcLwCrkBKEnTel4FfbwBXjL2f3\\\\\\\\\\\\\\\/KzosUAZ8aeTsFlawDUIBotYBir18ydbk2tXfI3i\\\\\\\\\\\\\\\/z1N7g8YfexOFYmIhrQave4hwEXzoCqg6R8ACA3cQy8VS9gXJ56EwauiEXWc+uxrXLxZaVnGu55eeBmHRS8BmYMLwh8+wvBog3bQIcFNIXuB5lAnxgtojizoA1KONPDkqKW\\\\\\\\\\\\\\\/xrHVHU1v9vjEqKOG6VdntVBT94+vHfQfLtV\\\\\\\\\\\\\\\/eJKPZiYEFLbmKva+Hur5fujIe3diygqQB03ojPZ3u8WennhUdMwRjmssKwvyTNIamlNiHpjzhSs+AVOZP0M6RvmylylotbtRV88n3CgIhJJ4R5k4OSzEH1xMtMQllsRStBSbGJybAz9KAM3nGy6BLtY\\\\\\\\\\\\\\\/+Tk4GMWqeXiiJTAd1Vp2+93fDAxetU6fg9EjcECRHx7p82Lvlqew+7sb74lKdws+xQIx3WmuUe7OvljKNVNlc\\\\\\\\\\\\\\\/BZEevwzBrzDg114RbFrH7sZZ8L9mOkAP+XQk8At34zMq0Q8eN7RewnPjQaHbI\\\\\\\\\\\\\\\/fIXhkNo\\\\\\\\\\\\\\\/E9LGPSQm0rNqfyThT6viWZkqK6dZBrMCgIKyPUePo228hxKFl+TlGVLiQSWvfN\\\\\\\\\\\\\\\/lDSuLSVv6ICJnXdYLnXoXWpnWyv88iYdSIaYYwW+eyxvpeo2bNzqSXaXRan9jbTEdVJSKNTwFhKGlrBe6cZZfp5+x8XslT50A8r1catyU1fwnQRXZJsgsG0uPqDNl7\\\\\\\\\\\\\\\/zBDigYj09+cA3VdRgQNMEKBqgCbES34o+HuGHjxnKxoAr8++TBGrTsBD8hNPR7q7WWp0x622\\\\\\\\\\\\\\\/ZY3htQt+7lDrIrccSO6lX7wSf5OZEAgKl3lRKcfUkkDNHya9\\\\\\\\\\\\\\\/A9x7ZBisQMs\\\\\\\\\\\\\\\/fcbGfvuNlDoc0xnjWmKv2B\\\\\\\\\\\\\\\/KoRpZzunwxr5P13XOkgLXgpBQ2sQeTaK1XO0xdwEeghEUhoxXMfS0efM30PyjrAizPZiuOhNtVCX4ZrKeIF6+bYBNAvy9vGZp5WFQnWkv5Am3T03chLraJSGk76RVMJdXoQK7hRd2on\\\\\\\\\\\\\\\/sVn9fzdqDmqdoJW42dOXPFPQHDv7xG9xLmr8D0f9g4g\\\\\\\\\\\\\\\/rJ+mWt3mVU9Ic+j7A=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ebn9Aj\\\\\\\\\\\\\\\/SAkmMOeQsIHZPcA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022f90b4962b85b728dbbb14f70bb8e0a91406daac580b3241eadda9dfd727b8db2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1441.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1441.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1297\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1297\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1297\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}