{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022IYepBckmmI+wxuMSxTpjVuC4xoKg\\\\\\\\\\\\\\\/8mMcID8egv5yoZUlLcYL2Mru\\\\\\\\\\\\\\\/3O8pnIuj\\\\\\\\\\\\\\\/6k54ewWShK3gRYYeX7l8yC5JK4kljDxzsJ6Z7uVgx3wcjfkRAemmcqlL4XduakNG8EZbk6riMYuBDk8eYIvFwSegf3pe+vFXrm+V8xzNgw49\\\\\\\\\\\\\\\/WQZ0VPTlYaQpwrBWnVbPbIpUcZ7S+gdit0sOKW3OwkcjM9OcV2T8h+hwpWnsyL68mAEGqVUYVaXux+DNsX2fPv\\\\\\\\\\\\\\\/kljO5R70\\\\\\\\\\\\\\\/1AjJZ0R3Zu7JPf47QQcf8jYyvBJBOKcjWPvqmFBCu5KpPxmLbOrJ+yJTkFWW+W9AP2PUzMvXudC5g950RSTXZjOpfQEBtP7qsXAdwGTXL3S0DtX0rUQeMFFd+IGb54gjdW7Yxz2tefOIq6mqYo7gw8+6DMx2+8atvGerlcZHVXwb513MTHxBSkDmOsrNWRujsDtKnQKb8c61kS6phRrMro8YghURANj1Gcytus\\\\\\\\\\\\\\\/cPOD4x2XJiJ\\\\\\\\\\\\\\\/MSFEwPvi5qRxsQ2ks\\\\\\\\\\\\\\\/h3W14MBwrJQa6nPs9Rb5nEkfZ3yTix24xSoNVTARaUciP\\\\\\\\\\\\\\\/l7037zbQPOEBY0MG+tswyboNmm0WoNgGWRU1vU0uX1z018igSGgWsvbQhXBhdXA4Ja9r9grgOcJgWYPbdoM88Rdr8AczZ3xweayNJcI7mgKUaZkRz2uonhz64XFm3+Fu30idraJWJZCbDr3G1UH4Kzgm9MsFfm7YrJeRTIIsPh7cYYqT6A5h5MGOM3PLc5qP+N3V3v1TJTPrUgDwMj8KDr3f8UpuiBZZjydF95PwAzdkhRZXdqZZYOP\\\\\\\\\\\\\\\/5qkoppdoXbJeKUEpjJEMCgxi0gUVTEgmfwRA0TNbolByuq9agZCANu0q7GMMId6LnRsVHAZuqiJEjNsf6JepjUQOV0pWKjGE6HBKAf4aFvxy2AgEhXvPMwMVHPVAAKhO4fkVpHlkt3A6nMvxXEKJhAcKP20YMOh610xTNk3ssUgVDk+sCIyNpDgAJ0sm909SKnU4BMSdLGoFgXd7kcKFa01VZf30s76+8akWUU3v71i+AkORx7RfC6\\\\\\\\\\\\\\\/wojb4KxZq1qpUSMSCeeLMXf3Qye8sI9cmmlFBYx6v34YVQNHiptjAzOqj8iiS\\\\\\\\\\\\\\\/GNym1b8UnRGiiyRaix+9PK0GBGs+w0cDA+iZiGvibjRms4l8OaWjunnm4AE8GLvqy2P7EmOhf31FD5XUuA+\\\\\\\\\\\\\\\/l4phcY4HLHyfXfRhgp5NrzCksbxjrm5\\\\\\\\\\\\\\\/G\\\\\\\\\\\\\\\/uM5b0j2LKRXAAGPVlomd\\\\\\\\\\\\\\\/ArpWMzB4ksUDIVDvW+\\\\\\\\\\\\\\\/2koegIuNmLn55gM3+vUmEE\\\\\\\\\\\\\\\/JrNPPeS0RHXKcJA1kqY8UxZdzM7NJmFPBpdtPtXDGquoogxJaKqQQprADSaTw7qvAVdeu\\\\\\\\\\\\\\\/SbXe91Ac4i27I6VUN\\\\\\\\\\\\\\\/GJzIjedvP74NV5bXgM2Erds+VDTPSVu41OeU9tmsFSAo9giCqOLfDqeYYPMtyhMwMwHXbnhnJ09TPaeEaUWtclMj0iwXQYQYd5u6UBnPP+Rlr8c22khCjaoq3Pcm6M1OnUb\\\\\\\\\\\\\\\/LOp0vvO9NYBUPgFwCkbrFFRDeJCnWIyodJW+wIfm23UvaL+Q8Yc\\\\\\\\\\\\\\\/lWxjKlu2QsRG1v+EoFNfukwegcI79fSWK1MlIUfWOfx1zPoVgj9l+KQ\\\\\\\\\\\\\\\/7+8HpVptrkwiNBdVNhgmdc3gN26blsUkU9j+5vslCoUmdgOQsn8dEBauTqtc77CtXMOmPxnH2Xu9Gwy\\\\\\\\\\\\\\\/Mu09fkbzDkdDlvSKd1xi3CzXndLJ+C5dsAE4X59ZDqB8AseeRsaIqhiiVnk7bBRVS+L2ndrVlGqz2r7Pfk1XsElPRz7watSp5dtCFEltEjSp0THjQVC3mDjEHfgvXhn3hvgtmcOUU9ZQUxg0B5h5q2Hb5ctHy+Xmn7x1sRko3HWDjjXNJux\\\\\\\\\\\\\\\/EiWdGh3lJeJ0E45WGZXpdsBocE1tO\\\\\\\\\\\\\\\/A9vZjHXDG6JBPE3odE0YW4HsyyxcMRoKfWp5C7Vfz57EFAkRcdcFMlh69GmPvC6cH1DkFM5KdJYtDXAg5o6meh69qQ374vYB2wrURv0w9VnWj6tzQEGLTnxN59nQLp39hvqwME9iufLW+U7T\\\\\\\\\\\\\\\/sU+gxRHFEjaq3Lfg4yEPJjfZmyaS69GKBWuKRKfTck4koWmLYTnPqPiWE\\\\\\\\\\\\\\\/po1s+PY3mHr6VUvvXgWti5n+BRjV5aOkv0YkCkqgYtlE8DsntiivGeFSLA8mZbuY7WOwnCH3kKwy9OknU5YYkDIuHMoauwOS87tIg8oxSVOLT1lQKO8L3zTUsXNK0rZb5pVs00lU2lvXhQtF8axiGPLkdADwPhZfWyqia+BCblHW56OgX56weFP2Gm4WOqPuug3uh2hfzTvyeV\\\\\\\\\\\\\\\/lmKmEn7JPQnrqCtkDgKvlRtnALQE0zqxa6MLFFHfMbfgetB7OfmRytz4Z1bWqYZXrK5Aa5HLvYkZIdopy8zMLj1+NeFKLAhU4zM6NmuxrUQBDzN4VpJXkKcWSmUIgW2Pz469ACYP8Fw0Pj5WjRTdJsnpQDDOOFXPjKcX1UX+p7ThAUlzL+A8YPwQQQjoNYjySS8+7hskLP1vfRL8GHIugI3oltfZhpsNsq4p3+k+z9QS686Lu3kk9SiN9rknlSYjEyggMA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ht9OdzSqn6Z1egd3FBQL7w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022cf585731c0efa6199e6f39a877aa46c864c87e3e5debaa1f0ae3d70b793eabed\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1449.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1449.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1304\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1304\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1304\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}