{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Slxa+KsGbY3COAkOpkrw61QaP\\\\\\\\\\\\\\\/mLLDK7qwzs7e74ZXGdkvmJVcl5jQeVRpr34H0UGiYqIbhj5A2t7kCK6hvLpKemWBnuNU4i7vl+0r8zoi4Ugc4KN5xyH8+T56Bm8veDG3fEcBCYtWPxtr+UOEGr+rKcNaC3n20xjKcrXX0HCHu6c87akUumI2202gktM9UyIxxRZiqtzVtIs9HqCFBO\\\\\\\\\\\\\\\/VEkj2XFTXQlPW8P6Qt4p+qinHP95NF7HB4vk4x3CTIbIpnp9jjZsV5L0VFIPVCBzphWui7k9A1pNPBj7mj4CejO4cwWtyN8LDap+KSybMvOneM2BGTeNa0aOvhP+sxXSk7gX8IwXucxAjRH+yxLvDBP8pmaKfm+o+kaxgSEv8wLqacgnR8PYMDOEGmPYADJbk0cWiylawLOepSA3DON+AQhhmh7em8CkaSJa12DG3WKOGGA5q6brL1nZGhgFRdQ6cMRKUvxycqg0uQes+\\\\\\\\\\\\\\\/ivs4WWW7cJi6gqA878H\\\\\\\\\\\\\\\/LMl3GwTiMPIuro\\\\\\\\\\\\\\\/vsKdbbiOxtoY6BX\\\\\\\\\\\\\\\/CSNSQ+I7S\\\\\\\\\\\\\\\/u2Q0O8+gPXP6+dqpxxD80M7CcucmTJttC\\\\\\\\\\\\\\\/vCgpBryeoCfCkVnKlXUfr7pr\\\\\\\\\\\\\\\/DMBlRnANHqKJ2rzTI9G2ma1sENVJbC5D0R9w5vExuoE\\\\\\\\\\\\\\\/09OjInCQTBt3z1fL8qDntCUWJkvnCi7Jl+otin2me3I198x\\\\\\\\\\\\\\\/smvI39jShKIf2mFmwXZZspOxKBvnXasZ0gnR5YHV2OOHu+dZ1Us8U3NjirUf9cXDjO49f0DeZ3CDJMl8lHii3WFD+02mzn\\\\\\\\\\\\\\\/mL\\\\\\\\\\\\\\\/6HflP+YREH5w5n\\\\\\\\\\\\\\\/OblqYdnrBEQduOGHw3hgaRoHOu\\\\\\\\\\\\\\\/IAzPENTiPcDxnh7c\\\\\\\\\\\\\\\/f2d329suCxocxZRcWnidm8rfQEvzSl5h6B6Jvh6nd0zwNnPRBBQsvRSGxjdqv\\\\\\\\\\\\\\\/r7CsY714S6NkfSfY1Mgm2m7rQkB1xj0BnkOZZncqELtmBRzs+ReMm\\\\\\\\\\\\\\\/gJZWahGu3VpScW6x4Q1eTOKXAvgV6q86b+ZTJZZoQ3ZF7UCNJqo9ycorFUP4MHHUtG9KHE5WuEEx\\\\\\\\\\\\\\\/kKw6EnNGtiH05AD9fsOrCVcc8\\\\\\\\\\\\\\\/RCgY7uquwgTIhx3HZXifCCx4DbJZQ6leemd7iQAh7Nq7i7hJEvh4RhX0lPFsWIQK4SOXHYsdVZ3\\\\\\\\\\\\\\\/j\\\\\\\\\\\\\\\/D+O6F\\\\\\\\\\\\\\\/bZUbD4scMTbUeWVBusUcNSGpuaiBobmTQwzTYbRZBuv\\\\\\\\\\\\\\\/bpN9g2zEXgxNZgLbq4wOyK8kkflh7D+ifeOitcGu6cPysqdD705liQAZbcKTENp1b7\\\\\\\\\\\\\\\/5KLssMFfbc0ig6XFDfl53ZflEC8xzof+yH0vUHYzISaDocu1vnbCRNTJ9gB+0acsp7nsBFI3XyAoYsuDprqfSne6iiMuj+9MVojQ5pHeFnurE\\\\\\\\\\\\\\\/Wv8ijVQptUHFzA3yOzLv3W4eLK4ZXRQW3cKxSg4ItDRYBShjsI9es+xUKSBxEbXgl41O3tgh3F+etA9d5vA4JPKpY9aNmLQTIxyING8WP\\\\\\\\\\\\\\\/tqUvRS51Gfu\\\\\\\\\\\\\\\/Mtvr8j2u1WcL4ttFZNGSfmY1ylICKcXkehOPD+0NZpFEz4a+bcZWNGLk1I3TN9ynzTW+EAdicUNKnFAON9cyljW10XGnoJ4kHMHgUQo9PdR2wo6MsKL4YDcu8GyRlUFxe5eX+edV608elIK1DMmi\\\\\\\\\\\\\\\/Bckoos0\\\\\\\\\\\\\\\/crh2OYTIL8uUBrLxUD8hk4nlvry9NclkA0\\\\\\\\\\\\\\\/0iG8tbQPD7bSAuJElNcEllRlIzTV6jnr28BWvEDIStJkuGiQn0U1Gj4hFkMGCbZ6FVoXA9O1s7UZ+99Dm79YtTnIw+nsVdtR280E45VnSUURCmbxy+zx17f+5WO4Qe9nrWut6wHp8ElHm1ud8HqPoB3Zox71h3\\\\\\\\\\\\\\\/HcHkpOpFLI7ZdCuiKFvFy2r7G2dunYd4cDNhEj9kwKJJQQuVX1bmwQqZXbSP3klBSNAmtNICW6S\\\\\\\\\\\\\\\/jf1qMLkC0Ni972n4jzKs1mRCHXErxkRlwzUSs3aUAZ79U\\\\\\\\\\\\\\\/jz3dihKBS4cgqycoIz0Ae3B1JdOeHeWqMFguhH0FCjSFjR+hGwrxvxjCK28uOS6FXdwkvbiZ72rOd6mrxgrwuBZz+DfnyoaPAsWgJi785p9pTR\\\\\\\\\\\\\\\/bQpcNVISP+g80Tq6L24m31tE+TiQ\\\\\\\\\\\\\\\/iTJWa2BGzdO2s3bfaEXc7I3AEb6RGnSk784zlYsSMkK7W4Tkc9+kSQvrmrX8wg5sy3up2PlWvec\\\\\\\\\\\\\\\/kKYBgQq41G7Pj4X31hFImvFZudvywoSrQFbhcy8EjIVE+jgxJfk1PTQlLQzqvEUIyCVjjlJ+LaDiVMqnMOnlX\\\\\\\\\\\\\\\/RHVZ4c58mBXlV9dRSKXey+LkR6SOo3EmKZiGexnwF\\\\\\\\\\\\\\\/Diw\\\\\\\\\\\\\\\/veRegg3QzaT20aD6OPVpNUluiZHkLaOG24tB9mTlVJ3y5Z20VvdNYQiShMJESV9FAZ6HUDuOaUfVw6lJXRdwDaU5\\\\\\\\\\\\\\\/xq9sgxcVkZLfy5j28gVScuoYuNoyYX7D8kl3zt69ShTh1gjAArCxrBBceG1Iz6WKqmXNfcUgNWQ4dZdehXRYrOc1Q\\\\\\\\\\\\\\\/uMiPTdQthRXXsKhgNvkmNxrlJPQ1KF\\\\\\\\\\\\\\\/4iaFKqgrEBPEZ\\\\\\\\\\\\\\\/UULU7O1e\\\\\\\\\\\\\\\/l0U1lbiCUFLdTPA1m153fZAPqzFzYbWYwgI0+1iBBGMh9AYlVe8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022T5DbiyBpjoYFm6IGSJimag==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a4b0bb424c0194e3f659bb143a03a772dce8cf1290a28ee876cd88a47645407e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1147.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1147.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1040\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1040\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1040\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}