{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022JUpRN7eZKuWpe\\\\\\\\\\\\\\\/cHSJgGvg5MdFTMSJtd3lPBoEcsDzq9TpfqXUsDMM0a3+fFMYySiqHGw2NmF3jX4eV2EOQrPmQMy5DQ6009nGis+dYHq6ztY1913sASFB8bo8ulz5EtObT\\\\\\\\\\\\\\\/r8RYVQidi+OP\\\\\\\\\\\\\\\/k3PQrYzCPTba5hYXD29xAPO6DXsNZFqnosSv+OjBMA7m5pdAQ256ebqQWmep3ts0Fyz\\\\\\\\\\\\\\\/B6RFyOwZb2Iuh7MskGyGGqyfWtljaSkyMibkbW05jp21ycf4h5cJuvookpmpGX6\\\\\\\\\\\\\\\/G7ENLMdbYUGP8XGedwoy4Y9gxK79dN473yt\\\\\\\\\\\\\\\/miEiZTJAAkpMI3ELs\\\\\\\\\\\\\\\/Hb\\\\\\\\\\\\\\\/VXMxKCdjOnNFvq8WYW\\\\\\\\\\\\\\\/cj8LGeqGCrh033o5SR1DW4jG\\\\\\\\\\\\\\\/BiXqPXmkPrmY1jakoQRc25K9YwjAcK6qaX7fUQCbS8u8S7uh6JyZ+70hyK0xPxD2olsK+szZpdVGv1tiFSxc2OmDoKzo5ZYbnwTaUILpE8RJOjd9\\\\\\\\\\\\\\\/D2GYMK59KdXK9q243\\\\\\\\\\\\\\\/HtgXOdM1qv9qJMquvcOjDfRMzL5v\\\\\\\\\\\\\\\/R7adCpZzAcJMonJRuv74yKcnodU0xlSwHPSsEBqXe7JJdgQRTJ0wW6vEywUUUhGEqTkJm7lMUWpcCraG1XtGAIzOnima29c1c8wCQQLdOVvCTYZkY3ypypaqV2qU5hXc5q7s2CUnFr330BySxMwFh6qmGpJRibqlefcSdjdQ6+A1+Rh7gtXx8larp4CHkmVe8beKV+Vt5IkXXaUwrU1wSJI9GXXKHgHRyBPbweuKgpWCdmXYNysVL96KGoDue2dVqHY4KW2T1BxCJdDW16mK944kMpFUxW0F8BwZS9TLAAGuEwGZeuTS9Gdjq4ncM+FoCT4vPd3m0+7sS35ETVi1a13k7zTDtL5LV7tAS38jSS\\\\\\\\\\\\\\\/GdFM3SO9JGbQFsq2jpzLBofQRS+doWA0ziCYkynxz6cCUblkAFVhpoxESGqyTUYlav3EXlTCXCn2e\\\\\\\\\\\\\\\/2ppMdB29Mbe\\\\\\\\\\\\\\\/e8I+1HbYIb+7TB3+hB0NzqfVBQnAGAAXpdEo+8etwTt3jmbhfRy6f+ZP4moHE+H8n75U85tDDybQ4DJfrv+KjFfZWKjHcMSliksgZplGvaSfFtr2DdTE\\\\\\\\\\\\\\\/+3V+qXyg021vbISDGCzGya8dfbd\\\\\\\\\\\\\\\/iLYOCxvvyvBqvGpRVF0SFPiAZo1neV1ATf2AIpdHf4woJL7l0WhKxTYjBrZ4adkErIFXRSuTWHju1k6JeUJGUbefBGP\\\\\\\\\\\\\\\/HZYz0Y3R2mwym3f2zV390+3u35zGx3ijhLk4As\\\\\\\\\\\\\\\/z62jaCgUuotISI7ty4B+dF+rtELnaMlHUXZYiMWid09J6VetuDSYevXUDt1MYD\\\\\\\\\\\\\\\/PZzPNbzb8BEfWVStTa4Jq72sh5uCTOuoYpycOQISo\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/8d8pm5GwbdIr70iruUc7GBiVHha8fbOIZ06hON\\\\\\\\\\\\\\\/6iAG99HD\\\\\\\\\\\\\\\/GP06yYWjsQe2usuZFLOqxSeKsbi3Sjqou4LHDjed9Q\\\\\\\\\\\\\\\/C1Da\\\\\\\\\\\\\\\/WquHix0Z2EHt8EdHh2l0ELd0QAKgfJkCC8xTApa68yQE4pz9PbbDvG0SvyyPIuqb8iUrTe9mnhLE7jq3yBGN\\\\\\\\\\\\\\\/8p+jfkAmIaAD7ZfcPgMdUhcM0FmOGQPctNMrHH4jTV8VGAiTX1UYuMTEVMzw3qDMXmqgAlEkMjo9sOxINUgxC3H9jg+0lyXYXd3FXXKjyBjNMLNfAekVKk6UkB8XAnRuKtbkWlk\\\\\\\\\\\\\\\/761CBN90uPIantszBcGzvyXw6UZTd\\\\\\\\\\\\\\\/y+30tloSelf3Buj\\\\\\\\\\\\\\\/PWe0PUYcPP8O0XFpaMmxHlZfxT0XriMEpYR6yFitoxSeJIn2hkSQEJgteG5U2gfBJ\\\\\\\\\\\\\\\/WAuSU7o+MYiCq6ikQZr0qoGTUOJwRqIwOlxMlJvBXFRhwRuF+yxFX7xLKgu+Xny0djsiFp\\\\\\\\\\\\\\\/EBymtLqpIl9AReBBmwwq4d5\\\\\\\\\\\\\\\/nglIj5Y1EPj+U7JvJGIABcF35Xe2yv1yarpc7mIMBeBW2o2DXDKV5ApMvBcHBGcGMwSaqiPzCY0kMNsGvgDWXx5Ej\\\\\\\\\\\\\\\/QcsVZwtas9JA46uvnGeltH1TpfL1GXBphsxaM2ov0LDlWzLkl7tKAcNB918VPISJbM4i2R2u7JwX5QuGZlhYdYjpirKBt8Wcb06YklIpu+Ub38S1Prll6PS72+Nt5roOLne3pOXhH3j1o+ChKhvkLU7QRY\\\\\\\\\\\\\\\/Olekm4imS6zAy\\\\\\\\\\\\\\\/FC74\\\\\\\\\\\\\\\/kAN7BKpCc+B3U36m0EHBPzUazaHwmXfirBGUaA7KCucsoYUOEG3GCszFYs+nTy3\\\\\\\\\\\\\\\/AdoXJ6EXfV2oRQYIslhNv6Nvr+vCqx\\\\\\\\\\\\\\\/zF981heUeIa5SUXbMpgBVZ8Ng5EyYW5YteDxtCQ+E6ktAqq9kmVRXIm+WS\\\\\\\\\\\\\\\/97fQ82zHPySKyZRXj8RNXyos4QvV\\\\\\\\\\\\\\\/2mt9BeDMLoDGbtAGAzYrMfNGOamehX7R\\\\\\\\\\\\\\\/1k1lS\\\\\\\\\\\\\\\/XD1qluIJ\\\\\\\\\\\\\\\/SuTHu7cJlCfL6QSG2PLI+bwXE8Uz2nz61OVwyAWnGnoG180e+Bpw6aEKf2k8OEPgPFsgUKR3Tcac88CHhqFpE7ENjl6g0vKs25+gUTUttS9rc8ApNSYhk03m6BJVuLeTFDZ7ANi7Z5ecvvI2IMBgvETYrVTuenl9XQtY6QeqCQvBLVs4jG0gMI9qrYWofok5bHrt5uRh5g3\\\\\\\\\\\\\\\/PQodXh4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022lymHA3WNctjys9hNIgCJRw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002204320913b414f5ecfdddb917a814306af8e8c90a3b5924e245d18625ceb10b62\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1511.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1511.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1357\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1357\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1357\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}