{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022QaKWxSWCBAd4lAndP8ucWLO1ObIpWOs5W3uJOYcVhTtkZ9DTEERLNyXn09zkYw8SFDUwm2L5DtTH\\\\\\\\\\\\\\\/i3BpsmTw8+dIbt50SbwabA+9QIR5ftZH\\\\\\\\\\\\\\\/qFdPwpa150GgWWDjFYAcGl\\\\\\\\\\\\\\\/fpqJwoG44WxBnsUGk91y0Y6gqelIVhXF97iaK67jhbbVy8jluAsJOsffC31VHn6Pxae4nf3WuPdTkktoC\\\\\\\\\\\\\\\/35nsoSEFSv6FCrfDU4DwkWC0fiw4jBnwDgHZCqTQRFbOaVBUI4Pn7tberPe6S3zjqpWIcqOWmOlXexjM7FIraXEMwGcpvXl5068YMWKHYzvji8mXRCJuop3SqkKoljJOj67jkqQ6eW1\\\\\\\\\\\\\\\/VtT\\\\\\\\\\\\\\\/vDQ7xa87cS\\\\\\\\\\\\\\\/w2byns3C9vDONE8\\\\\\\\\\\\\\\/GdOFvoIATFLGoZajUQpMOxKDtsQDLaKvhz9KB9tbnaNsw5KBiNXAEuJ\\\\\\\\\\\\\\\/6GAO5UmWSP2dMPmS1gM9Dze9GLOrPEF6igCdv\\\\\\\\\\\\\\\/t2tBR1+CY3l5o1cG\\\\\\\\\\\\\\\/TgkVrNDTHkjyna2gc5HSTDw702RwYzvKgc2bkE0wnVPjPcIA2C6oysYMjWV36u0VroUqyA5pfNf\\\\\\\\\\\\\\\/yAaqfQZ\\\\\\\\\\\\\\\/f36Q5PEx74Y1n+bwbeJ1n\\\\\\\\\\\\\\\/Km2O+9br6lhAeQ6OXh6MiS2+Pqv8gh\\\\\\\\\\\\\\\/lvRvPWbfBr93uFrdMtAQbXSLSAaqKYmYw2dabtFrQRAnqWKxECe8LaezFOd3LrBj5R9wRt0qPAVEgMsqdxY3SwhbKHtYUR4mW\\\\\\\\\\\\\\\/NxehdpnXNvTFft97VS2RKMsbonUabYDEPwIZlFXB+Dk9+hkRAFJMLt4Uv4moI\\\\\\\\\\\\\\\/2Hu8ba2DzZvYhEKZobeuUeywTVwyycAq3yO\\\\\\\\\\\\\\\/ltvjdArn8t4sj7Iqw3\\\\\\\\\\\\\\\/c1C80qBok3Dxo1oU19lR82LpljkQ1Ri+PAscCGVL44Lj8VRjmTMDI8C\\\\\\\\\\\\\\\/NcR2DGrRHBcFhQS7GSJxGR8eJefXeKyie3BUZOcZjJ67mn7zbIkSUMmZ44MULI53\\\\\\\\\\\\\\\/gBkZvLC1YEIqS01p9n1CVaGVEc+NVUCzwXgvGH573UbNkDsotDX8afs7HK5\\\\\\\\\\\\\\\/GA0DtIuZ\\\\\\\\\\\\\\\/eFDtGzmj4YNfUTIzSXT+dRwo5PgxCiAK19i01kA1vzQikcDLaV6MAO1SPl0BfI7mw4gzpvgVXJeWP+8oQfXJcRqJ1JE26gbtB5cKadQiE\\\\\\\\\\\\\\\/Iw6FRJFkzonSBtWAe9SdrF0CD5fLkUr+lVb01fFM0nYzs2IqxgtTSSvpQ9W3\\\\\\\\\\\\\\\/nSCKy6diBeVOdBpoT0bIFueTZGXke2C3\\\\\\\\\\\\\\\/c\\\\\\\\\\\\\\\/08AwBICSipMZhCxM+h0EX0tMgfxWamKLKTRe0CC\\\\\\\\\\\\\\\/X5Ltqh8NWlk+2fJpF0SGj9oh5t87QuVshGxwX0GYM\\\\\\\\\\\\\\\/46XrhDuskrx6EivYNaYgsPlo\\\\\\\\\\\\\\\/F2zZVCkmxk4PCBoNQZahCdwK2n5jOJwGbbhiAHRTgIvdCkvssw837aCpjwQT05D8BNMhpL7ZpKPygnKVgCEnNBsLT3jP5GilMz8GUUQXGmtPyLLFa6iG23HWFJSZbCJcrX1FLZ1i7T7jysWdG5eqj2CBpMFmQSAvLtS0L5nl3sAUujCuNuwxrZaCSlbDN2xsnA260dtyjt6lkDP4204n967MmLoG7Ne8gpfiBQ3B0xQLnxuADD3z3rpvoVoQSzEKP2ioAMdrAclhOOgxhyz8HhOlZIGkGhWntYNNPi5gwK48Nrx1rRvkCQvm3\\\\\\\\\\\\\\\/51cUEZIVnjZmvSQQgS241h7oHItd0hAm4Q41BG7XAsqdtC67KsqAHm8OzNYA0kr2YUu6Ge37z1aBvUCdVX7hBXZKAW5UUIHGjI0Q7BO9W8UPEVe4CuGnfX+ax4MyuSKu8IHJnHVAtr\\\\\\\\\\\\\\\/JJDp411CiObGZN\\\\\\\\\\\\\\\/81+sIbtXn+3B0chkBTPOY4AOlFDXI+e2q5NX4GESkvDHeH5xXPSRjiP03JRsZJu9zZlYqMMNsv4YwxVo1ZpFs6Xlecb0StYvydcktjhzuaN+RAhU6TW19tuK7+jFdirFjUFLebGCpJpFymSTp2qNfEhG0SxZa5HP6QNmYYDZrLLrEH3MU9OWgqyQXVVGIZHLf0EkhH0HWM9KynafOjeWGWyj0VU0\\\\\\\\\\\\\\\/G2DbRfgHqfM6bIqRgymxfOUoXSc8VMNn9MceHyh9ig5aU+mjI3dGHKiy7TlKCWXiz6AFyHuleHMtUklRnvkzA8OqFjkhBuvIE\\\\\\\\\\\\\\\/LCAHLcI8tcaoAZmG0VBstKrrK2yLDMOXnYm8sc849bq\\\\\\\\\\\\\\\/ASL4Gjj8dEaFAY1Z9UcsvDGyXH42ekH8w9pqvDltIVJ3HlMrSE4e8ZdoIektwU8j4y+UheLFCeDuZ5HHRFPwwFEjmAmw0WKfoFyeBejUNxa6ahhS3bbgqY3\\\\\\\\\\\\\\\/PEdoVF3PxEBsjn9e0y\\\\\\\\\\\\\\\/ZxmRxjJL2zuCMP6dwVgf4VWLt0DIuWzvBwId\\\\\\\\\\\\\\\/5eygRgnQG1+y4NyFSF6Kseya77HCp17EmFgXcVRKas39AZAijwCAFGpC1jt9uu\\\\\\\\\\\\\\\/w\\\\\\\\\\\\\\\/vUyEr7qUMKWpX75ccmeU4xcyDscp45fDqp1l5pzWbI4dwsXeAWQgiL9pczZXCylMh\\\\\\\\\\\\\\\/1saqeSuRCKk72UzpvZvNtJrexc51+bCcjETqerbdW4FkBWXIXVLMLcFSaYZHmaDN4ewqqQeWLQYRewg6FRTZ3A54EzeRvijgpSm5j4cI+qwSiv4f3GXo0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022woINTvEMQ6ycInKdY1EasQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b8384f7925654282319c7eb0ffa348fc539d7f956142e7c6f7590cbffbf6a56f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1210.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1210.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1099\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1099\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1099\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}