{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022hNRX18n36+8sukepYASOcMu9AKimQFxtYq8+BkZiqr9zVNKFqrLUPuBy\\\\\\\\\\\\\\\/dfvZhs2kmDr+x+MaCCBNcQwwBVxsMTPgVnn6lmawWzJll5sq4WWsOTuo9NkcuzbCFyDT5ovBB3\\\\\\\\\\\\\\\/tizyUJxj+ABU\\\\\\\\\\\\\\\/RrQxu\\\\\\\\\\\\\\\/rCG0TYiRY88nqQ+g0nJPvJ\\\\\\\\\\\\\\\/TsjeL\\\\\\\\\\\\\\\/7V6YBwl57HdSfHnrMlxad4p\\\\\\\\\\\\\\\/aadNJMVTLfiZirL4YGaLcCgmaMjKlgGcixWsQtM+os\\\\\\\\\\\\\\\/n2Ljq29SMLmvbgHteUhE12Y95n6QpVXMCm47LWOhaugSvKLezVm6CLHKqS3mFNyZ3RR9807WdIrmBgIUBq6Ie1PAKmnZVYQcE+Z32LrX0MkWX0THJRGvG9w9leW+HbIo9zp8kTFYk7pJFCmAf3CcveaxrEjt9\\\\\\\\\\\\\\\/hwexUBZ\\\\\\\\\\\\\\\/FXWunKQ8Za7rNcPtmJgOaM3GSQuyRdV5cSp4TYEfh6ZTuFQ1l9gilfXBRH7LN10NoopvgxFQkXAaSAn0YlLNLCjtGZNsc91T1nx+SZ0Ynhx6xDAFVBVWSzdRbkoewFRUXtmQkz\\\\\\\\\\\\\\\/UHqxLQwMcn3ZGnTdSKFVHdLXp\\\\\\\\\\\\\\\/jazaKYxtcw4Dkd6AB\\\\\\\\\\\\\\\/tSAUZQ0EtB8hoQzRpUPi9zdUfGvOyAcMo5I3kDaQhdtRU9B9DvpGDxyUfvx8exadK9YHHNGWWXT5XWiuAIpFIsycwktAJC3v0\\\\\\\\\\\\\\\/Lu6Eee8h89RnzZ0YdoWYnzve7pFQVyye2hMrE4h+a2MeRKq9QM4w3T2nPGHcj9kPavmhoC28teCiX4fKZgqFvIQBtaUMUvltoMijKhJPNzivbLVKsKbDT69V9AlnYOM8DenHGpriqrDtz1JiQTxufpZe8iBsyAl28\\\\\\\\\\\\\\\/jQmusXLib3BJ2ryaWLw6bQJcAp+MLOdqawXN12hJUuPxIqnp8\\\\\\\\\\\\\\\/HKh86Dqug6GmrQ7f8nOvTP7gjIXDGtmYARyETV6Ypyc1QsPQJurNb+Y6RDzECrL0tLX+stilEbRphg7fOZLk70bgaKlSn29vlcBv0JscIut9rmfDLVQmVgN0BG5HmYKD57I\\\\\\\\\\\\\\\/HDhZkSIcdaus9qEgAz8sCfKKAa5mTQ71\\\\\\\\\\\\\\\/MMM+HGNk9FfWetV5flmGB3SlkvBUfoabCHcp\\\\\\\\\\\\\\\/EBxqTohs7xTadplUysqyDYLXobwOF1QtxCnbWgswwZXx24MZXOvjKC7WJ0tQiVQZ0RBARiyKoF\\\\\\\\\\\\\\\/AnSii03cXw\\\\\\\\\\\\\\\/2PgRT9w0HxH0+8n4kOCv+vEE5QRHItRqVBe59LE0EK1stODc0Gbr8Rp8Cw5+CI4GlYROmvdAxUxp7euh1h1ymT+aMctkFttCoBcnOmlfw7uH4E8V38owttyhIKL3HjsHCyT77zueDSXzk0w0+IsiH8JN5IGgWzVn6YdH5OYD\\\\\\\\\\\\\\\/qZQJQiOAkNMbDtCPh87jtVjwZZDsn9IYYXM5Mm\\\\\\\\\\\\\\\/ZNUZuuwKgE2KaAogBiUquvEfGJZZK6rTTlh0HyP1UPaZghxU\\\\\\\\\\\\\\\/bqxt5\\\\\\\\\\\\\\\/n1K7Ieggmje+BJ4+5dxgZixItClYzq1hG995CfS4iFnQvt7Oq+06Z0LLKI1HNg8p0zAH9nGHoQztIVkBIJuiPach+XtYWGPWalMdMS0HwX7nfxXZ6mFWqkdBQzULh97owX6Of2f7eojmkbBWpSGGIgrLDftoyljfMTJR3li7JXCWpEMKafk3D\\\\\\\\\\\\\\\/wzVeDzAGU873A1RCQp+XcefCryMbIoxIArhnboQsWDQwn1sxONNsg6tyUZ9seJ4Sq2Hooq4INaZdP+Pp1yHVbzNp5Mo5ixy4ydnFmtWE4733POYcLxjiA6g22jAEprgyy\\\\\\\\\\\\\\\/vEZ49AIlLMduRzFBlHOLYpCv2jgIFqOXDdXHkAj2kZqOFkjjwTaeFqy2hPUTijrqkAYNyeOF2jXnFqJa9vncu+0x9Orw4IhgzjjglAH66AoYyg2UxnW8vQcAkurHJJxU2Ce7t1kIOWifSgo03km49deOeMMA9BPSKm\\\\\\\\\\\\\\\/Ms1Rb7VAGo7IegBet9r3IC4eBEHCsWfUa0gUOrSG9I8h8bORdP5Jfj2cMC4caDpwH4V9cXgVwkfoEl9UAx9kWE0a3EHE3sePWx9lxrvBvphAmivQELqbrwYMx6iX+uF19D56k9ISk4oqpYC2qXJ1sj6lEKIXowjlYgHvXLZUyV\\\\\\\\\\\\\\\/GeWqYlrXNzXsCjU15dXRuKuk1yHaw3Ffr+A3hkFXNGRKzwXS897oVGdb7d43b1bkFDz8a5JXaEVZ6iiZc+Gnq3BoKxqKdgHQdRX1sxra3S6lOPQl3DytOLykzCc0jW1j1bC7IOJntRjozMGVaiqlPffImpIHRo+wEDCUPIpBk0BICXOQ\\\\\\\\\\\\\\\/DdeZasLFIQ9FGQIDQsBqPgtMDchf8XQnX4g6P8y1Q8yK6lM\\\\\\\\\\\\\\\/6YSYcRA\\\\\\\\\\\\\\\/ts+XD\\\\\\\\\\\\\\\/B5dI5LR0u2w\\\\\\\\\\\\\\\/j9a9XWMU1nMzySXUb6B11HeJXGoxTi8DwKRDvZFbCQOD1Bw2eerJTcCxFL9a9\\\\\\\\\\\\\\\/qjxuHXfYdyJ0ZdPG89gMeCapV1LKBdDeqMi2N9C9E4H0Fl0y\\\\\\\\\\\\\\\/0jzAiA9n2MwqytF2ZtvTLN20aOXv38ibYfWNJFohVSs\\\\\\\\\\\\\\\/4xIA6N8kSKXl3tlUweBeTDBHqY47Mg3mRxsRpnjTNlvcOeFeQjrkbn9QmHHKoOp6wQv5e2sSDHZXWQk24nVl\\\\\\\\\\\\\\\/nd5yAYgTSjMKo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00224047V19NMocuv4bEGpP\\\\\\\\\\\\\\\/mg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00229a1aa6e49930b451e333f599f3a2d5219c901acd4627244006c8147c8905f3fe\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1152.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1152.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1045\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1045\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1045\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}