{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022s7UUJlRHHQ77mS\\\\\\\\\\\\\\\/XJjg19RYPHJL4IR9pH2BOra3kdKcil+yDvp\\\\\\\\\\\\\\\/8bIDM1qVz8WdqPHItdB+hZ43y4lzK9aA6utvVxdjgQJk0Mp+T7TzPfdwZltKuYQSLZs9upA12fTFkE\\\\\\\\\\\\\\\/w9ly92tp6hyfToI1cp3ugs0gulQA5Osu+7HGizS3BxlM0adifeQoyTh8kQZzmio8m8x\\\\\\\\\\\\\\\/QMhv4pRPkFFNggX0a2Rbv7bjjvr9a5ppNgKVAxQ+Oah4nJjuwL\\\\\\\\\\\\\\\/4kg0zLJ6ozBY3xr73DFZ4J5MTZQyWUtAEUJEHw3GvMQ1irEsjmjcRNgU7C9P0bSRA2MWqjcg5Wopb08xmHR4qULp\\\\\\\\\\\\\\\/vmzAWN6uSU82Rmc\\\\\\\\\\\\\\\/nDtXp8VuYIp4H1xEW0aMQOzKMzk2HrCgJC9r1RbVekZPJbbSP8XxchU1R6XtTKvOYYhWK0FQGDBMtd2zu\\\\\\\\\\\\\\\/4GrqNQI0KBh+AVltnF5wAwIZhjsZ46NLoGbmDQDTTF6i+GGgUEnWbzG\\\\\\\\\\\\\\\/f0eAjUlqghMBiya0yBeS9YR2lJUkv9VHGB9pHXknVpjoIwdDJdR097c92uZL3J\\\\\\\\\\\\\\\/Dcf206NNJQMV+CRJEIpy7qDwqf3PEzCJE\\\\\\\\\\\\\\\/Icmi705imNbNRJstzCW5Jp2vSw4397hdbZCENRDgXiKnFshgFK60w3f4izB3w3u98zb7NevunHoO+sHSUunC\\\\\\\\\\\\\\\/DJpIb2JBFaLnfhjtypPEkm2Yi\\\\\\\\\\\\\\\/exvicVgpuDI8UEklJRELihh5yAewEOPgtLumCVHqcEAYz1UgCAGwlfvJMYSWl9kfDc2xs45Kfu0UkzpKgmtpZU+0mjaQ8ZGLABCFdksvQPujPpl62fh2N+2cyDupFVDGrBitR6wOM3WlvsWE7X8nq9f0ZrASYUA1bb+0E3fdTrDBBq6yUVvpdvC7X6WFQ\\\\\\\\\\\\\\\/ijJws9nq9UEpUTx+BPML3fWpPFrbyKSssVqU03vwROFEcR0F\\\\\\\\\\\\\\\/hNmRZA1DTMK6Kpdi7KJXHGW8BVEqwH6IykPjxGdS8Om4iAJPmxs\\\\\\\\\\\\\\\/lSHd22cdKy6ihmGgcvGT8ytJGFDCgVKJTW4duNOS2R9vSV5\\\\\\\\\\\\\\\/NsPJJovttj0NFB+8DQsEccBKkw3zcfI3MOG7Oin5x8+PaMQ9K5VfOV6bctcwvWyTY7iuTdeAzV65jo478XsuNdtxKifV37Mzj2nlzo7gNSSF2L\\\\\\\\\\\\\\\/xwr4jtMZVcn2dmbe1cbYVhn3lhCyzD8tgastI\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/U0eOlGWspNjDLTPRNYfY1De1zdNOfn0JrFAaA6oRpbMq4eA6BkLixDc3U+4tNnpVGTvMJ\\\\\\\\\\\\\\\/9oZ2KWO8Em8Q0hs+bS3x0tSy+ID12sOwDF3vj4\\\\\\\\\\\\\\\/DHZ7ncB7hRHaXKMouAg1tXLb\\\\\\\\\\\\\\\/VoBnde1cYw4j3jD1Uw27f96Pet8P1SNQF7i6TU4ACidBbaphCUSu5TcZup3ijzwzjbgN2yuAcg6rq7ktpgwlDbFW1It46dcia39m5U8VGyFc4BXwtbUNIcdo0eQXQs8o3bZWW16ijamX\\\\\\\\\\\\\\\/P7Hh55b6BO2\\\\\\\\\\\\\\\/HTYcRwXBU4AffskQgqu8nwZ8XRUuWRFtr48+xtcRT9ygxbL9cuGWXae0XIaHnLinvVHw1eIgW8rdvbPzuMP5Fex71VAtINVT+o7mVwAYdXj5UfNN2+edbN9h1VKEPfMQWjwMHCImQiIAqovChNtsJJL6sy5Q\\\\\\\\\\\\\\\/pXGor\\\\\\\\\\\\\\\/qd1ThyGgtp\\\\\\\\\\\\\\\/cnjcFK7ULpwXKToFr2xsSKOTsL32GwHOX++JRllCMwBf28OTMLoYSeXO48ned3U8DVXi\\\\\\\\\\\\\\\/tZlK5Bzrc5hr8FBKCHXRTSsHv0kVKFrVvEAwT0pcST\\\\\\\\\\\\\\\/ajXIWa53GteGb0zVCapYf4+oisvlDlYA9eqMwcKxxD3IWQzd\\\\\\\\\\\\\\\/5wuc4MOMMpe2EdCXmST3CryE2YDChGXMxXKRkSRZxa41g03mNM7dGzUf\\\\\\\\\\\\\\\/oSVEPloQBdrADVW951mMWfJs+T7GbBvW1eESmMR95LLAj\\\\\\\\\\\\\\\/eqykm+H+ghxS0eFgCMOlOwdVHfMibcVMz86EYvFs62gE2ZVtkxeTlA4iYPTvyatDmCvMYc8jS5sJwmFa4B2pXCklHTav2tNOoCvw4IJibDQN+9OP6ryarMiy4UMe\\\\\\\\\\\\\\\/dH0UROOKqtoLDCJL5vDrwYDcjCLTfV1G3P0SH5a1hAMbkSIn0HZk8zlXNCbYTO0PViWSv44nVEr0rbpYQDR29uo98\\\\\\\\\\\\\\\/ZYwleYuc93VR8tsBLAw9gL9kNYEO2BD7LI7+BkLzpECK2cUXtl7MKtNQtp8EAiFA9d1iHUIGQFBmVMOUmz9Lz2D2uBG+5uOl381xS6FMTk8ga5tzFyt\\\\\\\\\\\\\\\/vwEkPRxLmRdm7cldwQWaVqG+xZBwY69tcogytoY+D+TxNWdfe4qnoHtS8\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/6w3\\\\\\\\\\\\\\\/BzKELfSdqA0eGapK7T7XAvzoekgHrVA2GdfnGanQIHxUFVmeCvR3KwW6qvFgMRWPv1FGpIxBn5p6xIt5GkW64RHUDFD\\\\\\\\\\\\\\\/d20lCHJ3fYDHUNcdayETZdAeaUz5zbWET4fgJqsX42ao2A+oabuAYq+LY9xXp\\\\\\\\\\\\\\\/Z5hSLSKEf\\\\\\\\\\\\\\\/KCp6e+HKU1iE0MF7PmiKnlpJsQCRMW+\\\\\\\\\\\\\\\/9t3I93MXfbhJNVSPg6kzMnDkXGmJkRGmpQuyaYl+h+8aAcpgKVIssQ0j4ZNAIiMitUGHuMAkcjxXhBnMQ5hzxmTOTla1bm4HnZg=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022yBcVw3XIiz+DfzBWV8K85w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022722feeaa128fc844774a55f9a78031ddbc2194d5cf23ae8946e5d8776d8186fd\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1598.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1598.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1435\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1435\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1435\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}