{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022E+IMFGdotrEvKEOjVy9WczYvMJpca+teIbZW9DjwARU35TdzBP\\\\\\\\\\\\\\\/BZZiROw2076coCeNbE4Xch7QSXoLuc+cBzXnHGfh8dNVthm+BRwoNo1SFjR8uX9xbhHpvd+BUnTblBPz8ALC37z5PMWGFWzV8VM6wIJXVItCat8keBXc0lbcMU+lzfv2fL3JVmKSo2LH6qVJhqhAyLm2SUfuGbXTmh6DKAV46pC5dJSHzjWynuLBOIIRqMrMPJPQDemkI5slgDEldgGZ5y0znFiJY6v79maaRxlqPq3vHBeTA0I7AaTThG7PvJ+Jtuprd5wkmBKO822iBsg2KMxr0TKXmTFKZFo3KilqsPnxHSlukqpcojThBmG1Mz8ZEwg+du5oTyFenqHcOhUvyrS6kI++4Apk+njJtYpXfpBDKgLwTcsmUzZXkeVjDzsLO654AKOU8BUBmYLTle\\\\\\\\\\\\\\\/DlnMNOJ1CvKaDrB1B+NnEHi61+pcrpmXQ3H3LktDqHUe2D9zy8jG1SukiCAVzyxO1N\\\\\\\\\\\\\\\/jYSkdZEWSqr1xSDjmHYWCcOuTcdDgv4\\\\\\\\\\\\\\\/BlW6TImnIow3TshXOnTom2wzgzu2NEPjn9hfS8BoBH72nKhlflZnqGP0vQumiUeQKRvG2y7WYFj+RBbLXMAX1ZPEO8VQc74NE8PJVW5ZqqD39e6kaCwYXDVHH8gpBre7rL8DACCIh1hdrU\\\\\\\\\\\\\\\/RMybxrmESSaxjdNDahSDVonHxiuvEwu32JXaNtVUZzp8NDGxxg0A\\\\\\\\\\\\\\\/YxSR6QOgvU2riwDwz\\\\\\\\\\\\\\\/XllG2QueatqWO84D1HxzPrwezSH1EM4jz\\\\\\\\\\\\\\\/GPj+RF9rFc0dyU0qMJApHYfj7OUhCXoLCfLZjBLmWYNATcsS30d+nc2sLeSJdTRT6UdCY5Uup+bzGFYF3GR9fT3D9\\\\\\\\\\\\\\\/or0xCYFROyoeGMyxayJuG0uAXvPefdSu4K3QYw1kJYbqdxP17omTLMOvu9DLImKqmFC3N+bB9H+\\\\\\\\\\\\\\\/44ssjriwv4S\\\\\\\\\\\\\\\/b1RavzDLUZc4+tg2Is5nO\\\\\\\\\\\\\\\/TF1pt2Qc\\\\\\\\\\\\\\\/mRMfWm9FDTSBb2jbA\\\\\\\\\\\\\\\/cVIxozfh+8dkOe6U1UDzy7Oclrsw8Z6pxmckHlHwP7B77QlX086xpuAcdg6qfXs6BIGMFR0yfWnfPWCzpnL0mTFnOvUOm5B2eD\\\\\\\\\\\\\\\/oC68EFEgj2xepFo1faGku1X20okKpO1FIxE\\\\\\\\\\\\\\\/NmGuHVsbfH6ToqSf7F65u5EXZytwd4fizZ1k0Oqf9SiaY\\\\\\\\\\\\\\\/WvmIqY4R9a1L6HdYHCWCIi9YC7xBiVfAic8zFeHWGulnBiZetpI+eXiRB8FkWpCyIwmaN3FJ5H3z1SXYrwnT9EXCsVni6oxpxJU\\\\\\\\\\\\\\\/9Cd\\\\\\\\\\\\\\\/bBGKxoiEyRKkpw02AtoQB6YVigX10FCPrmSSt42cxSFCczQdwKGzZVljVvmrhGg8qwKigeGQTC2PAR0NPZXxpOr63pWTPuWknTSPSlH9HGQVrptS1ibZkXBNCrJQpkUcIUnxutirmsIgLj5R9fhkI70vbj9oLMz9vG1Xtt+VRCE2pwIY4OAkxRlPridsQfKfQxHHP3H8WbxjtwMzlQYRXYj5bxXnclSrd5fI8w3hxNptVHVMIvwh1+88ZSoSNbiYgJ5MtVImKdK8HulvLDuvnxFAFpjdwaDYHvnFrs20Pxu14rZFjOKuFj7Nabt6ED\\\\\\\\\\\\\\\/EiHpqWlGN\\\\\\\\\\\\\\\/ElBheEkr\\\\\\\\\\\\\\\/5kE2opFSLTbyF2Q7Oncmb9464lp03HoR2uO\\\\\\\\\\\\\\\/lP5OcaAFGefRxz2T4HCxUS6i\\\\\\\\\\\\\\\/U0rF2MKVucdb4bl8+DYSYNHBcYO68HN\\\\\\\\\\\\\\\/AcvVQds6qwGuLdy9zs+e1ZIpWoelYGTPk9vUwJAaAnBBS5BcVXYDeW6ODkTlnrF\\\\\\\\\\\\\\\/yzQe81Dr9HDPKjzTWm2dnfrTEcOu2D2p\\\\\\\\\\\\\\\/DbwMSAIfXfpadiC\\\\\\\\\\\\\\\/3RQaLG\\\\\\\\\\\\\\\/izn04naHUP\\\\\\\\\\\\\\\/QucNjIMbTKSTtmCfw\\\\\\\\\\\\\\\/MC1rcEWaJQXNu\\\\\\\\\\\\\\\/lEYh67SdW\\\\\\\\\\\\\\\/3N3xx+ZXbkHWWk\\\\\\\\\\\\\\\/P9\\\\\\\\\\\\\\\/7NDoD5YqCmQrRPpYc+ITs\\\\\\\\\\\\\\\/jCsmKFUSyuWgzPX7nTYXt0LfunR+44YmcJL4hBeTVabu+FdhcoyAh5hqW8IQaXEXVxtmx5BDXJUyxyBhs8ubtK+Y9Ll5PM4PtIhZnhpxsyynMx33LPc7yUCwVVbG7vikSGehjhCLHJ3IkOUT4ExKtdtFMY9ZaNtJhD+izZE3t6ioHyNOjcDQLYzdzIJCowaQ1z+OrD8MILZuOqujsGtVklt71+z0HC1QaQ4+GIenih68MuxCXsoMmUuievTmoiMpWLn5b4uT+OaN\\\\\\\\\\\\\\\/xUZ5vH11tVXLRay1UtLVWWpWRmFxbV75emVsOyxbTxHsGw0+\\\\\\\\\\\\\\\/R8e58zyIXu5ozFwHwzM1gJenXQuBWi77ux1DHaMb4vBfUVeNhy3L06waD3ZTXXR1\\\\\\\\\\\\\\\/eyCHZYJcrNTTJhGdxJyf\\\\\\\\\\\\\\\/XoFiCX9e8aLwyCOaZVaednD6uaKJsGwmXrJktrliiee4JfvRo1Q\\\\\\\\\\\\\\\/dxpGAdEFpStdAXdUqEDfA8r8FJKtaGWBPEjpGgXmTDjYbPK2qe\\\\\\\\\\\\\\\/zYvPU+Nn6hkdhE\\\\\\\\\\\\\\\/yoCtClD0QXqrJ5gPYFQzm7xOylwmguXA2ggMHjQITm46cJs9yxxY55KzNQjRiWZqj7JEDvc3dgt9Wa5RphAQ85CZbezJ9j3uJEuQMHEpgQQL5ga6JP9YXT4cYbjc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022xpH5lpYOuSr27xbpuuq0iQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022492c0178030e44c364e2bc5a9f7a3b148e81852ba66ddc3b46c681f38bb3c352\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1013.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1013.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0911\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0911\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0911\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}