{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00228HJszFEOymJSkSm\\\\\\\\\\\\\\\/J9tpegZvL8SG8M6e1cmnZ5BhIZatgJqJxGQ2w6AucxipHNRvlsL04XDT0tL7BkEm3zMwyTfQ4gvQNae\\\\\\\\\\\\\\\/3UTVtRsfRTBRSzy27Huh3vIb0fVStqrZpJ9dWe7YX66jvd0Xs0m0LeGmSTGEa3XbrF654\\\\\\\\\\\\\\\/Aq6GFUwKuvAHJeZjw0XiuoGQ4epuKF7Q1M4z7uSccr6MZDABt7JSv9Xu74KQCgamKcvA3LPgNGg\\\\\\\\\\\\\\\/i8pa1wGAuLtj1D4TQmuEg152e30DNirY2jJlfhFVWNjkE9lGzePEb3w81wa8tAN7S65Vxt+ytpL\\\\\\\\\\\\\\\/jI82jV4U4OCcY2rIZg5Aw6BKStEWtgodcxoi\\\\\\\\\\\\\\\/tskgu5In\\\\\\\\\\\\\\\/N4thHtmBw4H1rr9FCYSvrOdRMKF7oq58hWYvBTWjbBE5rHY5GxIeX0Yn9gTvunMy7DvU2z+Oz9t4LmvrFanfb1T\\\\\\\\\\\\\\\/GnoErSNOWlZjHE9VEjrqJsL0v+P3eQhqm5OB3PhpBQ3SQWI4afEDrmk28Sk+Dk\\\\\\\\\\\\\\\/EIEyr\\\\\\\\\\\\\\\/wH0osWzh6DCUb3MYgM29lesTyRRWDepldOJ8sV\\\\\\\\\\\\\\\/rtD73EIbFRFRe4f1vxkL50zeTFBVnXEJMjRuhCND8ZA6ZTGQ7QA98ujQIv0ySQsD+0xoP+uzeF6SlYAbYgmAT1mhSYLSvGlFgCKl\\\\\\\\\\\\\\\/Q4LcCzhZkXDcKdSlmTflmhBhUD\\\\\\\\\\\\\\\/+HhTpPcZfeyirapQgpZc59zDIE91vGHVgqecSeKOpYY8X+3LN4QSQMtoaPZeNNxO2ae4ayt1yCe5Gv9bPPLc2+2lFEluN2kO7TxPOahUDMXMhGEe48IPgv2xbvP3QgeG+xqH2Aj0cSv7hjvGH6CpKfaqUxMtHn2QgIDtr20MqQqbRqgWJ4gBSZ+hByzjjtdBMBwLXHd+0fiQhCXimlpVnLl3vxF6zJrHm8BzG9qwABaWv+Bqofgbpt9hvV+aPfj243SuBceeTItkXLSZa7eOVqjqITk04Nly4O73F8Hl2Ujn485TqJ3THDterjvqsuTmbkGqusnAQ796IXsBEPvoYTr2NIlxLzuJbZyxkDjwmgqdL1BnvqJfjl2BAreKPatbo9wWyLtGmMEb+707T7\\\\\\\\\\\\\\\/5F46K1RmtJpIQVmAm9Pxqx2ObY7Jh1xv6L1PC1uCoWH+aPNvW9L6QbiBUThiwjQ2i2LPhNRohpyyUcey5RZ3qbHF4\\\\\\\\\\\\\\\/eJ39eW53vvRZI516zCfGai9xSf1mWSjGdcDAmHWTfJGyl7pQz5q\\\\\\\\\\\\\\\/+ms682TWq0EIf6B6OZdEGaspEprI4hSiF2r2DPSm7A7Q6ePcfWUUrm8NRM6iPMyVSuxEQIWaJtVe6o88IjtMwpBRlsWqt1y3QOqVzI\\\\\\\\\\\\\\\/esxw1GEoWohWdOVpCoNbb8Z7m7tcLKrrzAx65\\\\\\\\\\\\\\\/1BgwRGCQEm+s2pYRNUMVnuwa1PwbYS\\\\\\\\\\\\\\\/+9LTgckzDQSwKp0JHnZPCr6u8C\\\\\\\\\\\\\\\/JxABK39r5YM0zg1NXb2sU\\\\\\\\\\\\\\\/Cxt5pQV5U8Fsdt9pZn\\\\\\\\\\\\\\\/69yRm5Hy7SXNhQs1gmB605Y1IYoMK8w4lrfpa9H8llKAO1FR3gt4sM\\\\\\\\\\\\\\\/mm2ZN4cP4xINg6N+KBO\\\\\\\\\\\\\\\/1CgCG4D6BAuISy3MJlujsihTjLsDKWlfcPdYQxqxBdGngVW+UrbXJ0Zox8LkYjHB\\\\\\\\\\\\\\\/6qisL+eXGUXxiFZ0gLDLFOz4HqTt34rY60kEe5EyTbgoQDkG4+ODjjmeI5RZd9WT\\\\\\\\\\\\\\\/BwXEaU45C4kQyh37gXCRiuVJsh94vOGvJFJ13jTpvfnyarxuijdqeqD437lWrgsE8evxG3MAwN1g0R5f8NVlGjC9+5fnLkI7LsLr0IcO3xd+2n9OEKDkaaQw84FpEraZw0hlah3A62LJ80xe74Nkb6D1mridoTL9sPjDgYbcFCEag\\\\\\\\\\\\\\\/HLU4AZsgIEzZlaSG2A5cXpQxcmvRzZUF3jIlqa2EGsXfqqXv\\\\\\\\\\\\\\\/DgI+s2436haDSumzzpeDZV0EEQrwv9yHuQFHSWjJEWhEeOJKnRnciHsdwkDZPS03mb3A3kU9LKVCAtbt2C3jw+Tr6R94T3ZciZbml9Bn\\\\\\\\\\\\\\\/lrpgGJVkePBLEi0yUT\\\\\\\\\\\\\\\/kxZ44RijBNxvN8JavSrsoIWXpCag4UB2xGnNhzri5kADiaAGfx1KDicAtpF83B++qnQC+RFtF0lsU\\\\\\\\\\\\\\\/Bq2DexUBSnGwIa2uRZ9nW1eAvhhSXHYyzp7No53RWB6Fr495b8pe1Ko0A9uD7GfXNwMDgp17Xu1v+Bqz6XSlJU2ZNls4kPZnCChzhMnE99M58fvqCnOMHbRSlGB9VvWmYLhR43GsG3ysMeQtrVA0+aKUnZM9pDikJq7oe3GBwRJRYvcGzvK5aWktA7bost7jif6jQuxmqkSOWdubUtD7E8sJtxPLuSWPZO8r2voFO4Nj+MFlEFHzz1KOYhgO8BlfZQaOTzXSUwFBZDS9bfQrd3mi2N1QPH\\\\\\\\\\\\\\\/TDEMTzMA5KV1UrTUk8COATc5du0JAYkDHg8gw8erX8YLxh6NB2gTj+CYWcJHloQeaPUR5zwtKEzZgGxUzaWrNzLWeE2\\\\\\\\\\\\\\\/MG4HYm\\\\\\\\\\\\\\\/ztTAzLU4pw7XsqlIY4SsAPbCXdrZYN19nxCLBgl6nlUZCbXCItfVaACjJ8TVab8EwMI28Rud9D7YB3iEBB95jC8U8bkgkTx3bKsA+OABBnrNGLz8qQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022hCiVXwMZ\\\\\\\\\\\\\\\/JzpODxdJXOO3w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022757f2c4fbc47040f926cc84b577f5fb6326e27c80504e205978596afe0c98c11\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A945.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A945.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0847\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0847\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0847\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}