{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022bM0ClSwWpERQmEog6DS3867EHwlUSYTzwrxLbbfFxM0D3ubR5fOQJ5XwKGurKEt4fSpF7\\\\\\\\\\\\\\\/UQgE03G7bSVv3ugEiDmNDupIibL\\\\\\\\\\\\\\\/MBfPmTyDT0L8UgX47aVBkCIB2GaHdtmPa\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/s5WROByzJGhwIGG1LUewkEtgPQU3lj0eFCwowJTA8qs16N24fNFLDnUWp1S+e7eDF5kUljfQvxJJvLaYts6bIpp\\\\\\\\\\\\\\\/pikM5ppMtubPO7yOZ2JJ1EGlX3KMuv1MoVUtCJRrMT8\\\\\\\\\\\\\\\/ShSGgAVBxaK3hMgR+WfOLEk20xnvXkvNtZfLzZ3MygbJXNe3mFWwR+bdihBO1SJbRPVwwlGJMFMZFnGDHZD+PBoj04dU97CxWQfUiiX\\\\\\\\\\\\\\\/pBDalLdRaDVxDHwFDAxVmgh+KlwExSYQbasmDeSz3+HSzwMfxJPzjXuPG1izTPpRqYQ3\\\\\\\\\\\\\\\/Z0aLM\\\\\\\\\\\\\\\/gilG8qNZyihiup53UI8b0xzGYmAEI6yfyCrUa6Xy6dSTGJW8NYv5NIbrjQcFWASkyYzQ6ZwLim+RPgkw93sIeHbKyt1lfPD7pHgnx66aet\\\\\\\\\\\\\\\/VZpwOTzM8P1+2qrbyyK5qaSRGDbyaeOjZvWrDHAjLv8PL9R3N+pYacycCsi8zGk2FZGWbfcLO93P2xYTqJjKXKx0y+1Pq4dc628mTEv7fUXcpcG8uPQPatlG\\\\\\\\\\\\\\\/yz5iFl+IiA0xfMFukyG6O4AItkOdyUhsk76kP81gsGLxMt0OEJTQO0vD28dxdIczXqLPH7x0zQHQWE\\\\\\\\\\\\\\\/XGWFfIR722qwffG1w4Dg9xffarXj3VP91Hh7BVTzaJSPjt+tgh8gBtJa5lNZfsgVqu4r64D0g1S9HioL786YmruZlthCsxrcPteaNXFYn2odMlXBXvOUGFzEp7tGdQ2H6U\\\\\\\\\\\\\\\/pNfDwuCswcCRcPbrFJOzU37SjCzEust+GUXW9gRyhVIRfy8XOwfToox5p8MgheBXCj2RWjJpvKKujp7cSgY8UP7gHIJupgnz61nMjfMtDhdteDX+6CZpfke2qH40MYTWTMlHAhZ4DGYcnpTn0aJ4uRR\\\\\\\\\\\\\\\/I6gUD604hiObCMOxV0uDwtAb+Ok\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/6qF1QjH20TOmk6uDcU7hCV5m4U9YZIVx2OvihPWQ0AJ4bxOVZOCfBpB+aBR6BTgYFgFbR3SGLN7o52iZOlL6ECeqBheIJIik6OI77z9pEyDjYFG2upERhbqIIEGvhS7VWDWZj3yXX7DYs0a78bQ0mUkXlDpMpXli2G5efQKX4tn3Ac1pKR77gAO5yDAZP57qeMzebGOmE4wn9JEsr0YE9s7aWWO77bkoyW3HaZLoCSZfR5yNHib2osjBH49IfN0+pVkkwh7VI\\\\\\\\\\\\\\\/1eivUOMBFGrxuHk4GJjyhkPpvp9ZrwPA5k6r10OFM2aeMcG4pC74pL8Ah9mLSrpVSjZTylVVJlz5ONu1HUYaXJLMqCTGTUEdFLv9YnCRMMefvaBGHiDTU8Ud+Wta09slHL61g9bhD7BctTnURiMbY1WBuZXm3MgFmm4oykC+anbSba9EPnG0JLTbiZYwCrwSO\\\\\\\\\\\\\\\/ofpmXv1+DPO1mCCY1L+tedQb03YYmWvzBUMeKETTbJxnB3P\\\\\\\\\\\\\\\/DBUkb4lQsCEjmby1n6Sa4FoR16InfrQkSNbNKQoMflcFRoKxXX8lCu9NqBQJuYkNjgeaFWR1v8hfPrn4nOhJlPsddlrlUE45XH1KazPJK4bbfXdYspv9W2QUHBlIBpa6LRZWQULZVyQM9r94Qaw6WBSsbhO93DKTqTL9pDKMRtgobxkAM7z4gThXpgBl0apwQRZjIsgAbSjps+ydhJ6YpaaZovE\\\\\\\\\\\\\\\/SpCkoCK5oSzhPUcoDej76P1kQpBqdTEOzWsLG8GJEnpetCebL\\\\\\\\\\\\\\\/5Gtg4yowwmk+eLFc9azb99LaysDQRduPWuXZZPbrDSUqcwUqVOsQPcJIeYVI+RajZkO5HzHViN8WL5sTUpNgFmX9QQouX+R8jHBPAEscaTXrGAl48PDSOdETevk9X+e\\\\\\\\\\\\\\\/qUBkN68jRObQ0cViGmsTn9Z6rL9rHToI6ypjCcuEMu1CH\\\\\\\\\\\\\\\/45uk63G1+PO91zr5p0rd38GL5rmxzQmRfIbIbGFYkRQwarpHKAjCTUz+HjP2a0BqQ52GshgJkGZ9W1aHqZFgq4wsOJMrA8O2fcrjhOmS03E5qJmcD+\\\\\\\\\\\\\\\/2mywW1kG0otWQzRTuBiycFqh5oEqGe4GT3ZUQ6UZ4t+yYPwsIoSWreVIgZtdtya0HLWCOuwlqPEIzKNpc0GjZWpLOHEh8Prw+P7NBnSxf+uz2ABmZrRNe5PdS1NLEio1ahlMOha8peiWoyiuW198gBYQESpZeENccl61Ld8tT0jGsNQJlNEqRcl4XMDs2iEVUoqtgLxpjNYagzjMKrgg35+CJNU978w8M7EyBYvkcMt5EIB+s2cmEPsbu5hgi8fNZKUmCFCyke6fVaOJmzZNoMBvLwgIydJrwfh5+zSRkUEM9M4AU8nRE8usE7sKQIgpzlQL40YZ\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/3In3x4716e1+m0ZZ6hbBfyWgW8FXkC72eZTWWPRrQsLDVLDXxRDI5HD7DbFNDU1+\\\\\\\\\\\\\\\/quEaUkn7r+GWx1KGfDW2HboFgXAKmq9O0RJY8KY7d0tt\\\\\\\\\\\\\\\/XLUDreJGVe+k7B4k3\\\\\\\\\\\\\\\/DHQiWJmUOTz9HWA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00229bwaEJYcF40Rxg6dtNFhtQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022737231b984b71767038a995504a3221f14ff29d74780e8567d7b379248577b50\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A105.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A105.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0092\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0092\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0092\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}